Antioxidants inhibit tumor necrosis factor-α mediated stimulation of interleukin-8, monocyte chemoattractant protein-1, and collagenase expression in cultured human synovial cells

Journal of Rheumatology

Volumn 23, Issue 3, 1996, Pages 432-438

  Sato, Motoyoshi ^a   Miyazaki, Takashi ^a   Nagaya, Takashi ^a   Murata, Yoshiharu ^a   Ida, Nobuo ^c   Maeda, Kenji ^b   Seo, Hisao ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c TORAY INDUSTRIES INC   (Japan)

Author keywords

antioxidants; Nuclear factor kappa B; Proinflammatory cytokines; Rheumatoid arthritis; Synovial cells; Tumor necrosis factor alpha

Indexed keywords

2 OXO 4 THIAZOLIDINECARBOXYLIC ACID; ACETYLCYSTEINE; ANTIOXIDANT; COLLAGENASE; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SYNOVIOCYTE;

ACETYLCYSTEINE; ANTIOXIDANTS; ARTHRITIS, RHEUMATOID; CELLS, CULTURED; CHEMOKINE CCL2; COLLAGENASES; FREE RADICAL SCAVENGERS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; HYDROGEN PEROXIDE; INTERLEUKIN-8; NF-KAPPA B; PYRROLIDONECARBOXYLIC ACID; RNA, MESSENGER; SYNOVIAL MEMBRANE; THIAZOLES; THIAZOLIDINES; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0029880123     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Harris EJ: Rheumatoid arthritis: Pathophysiology and implications for therapy. N Eng J Med 1990;322.1277-89.
2. Brennan FM, Field M, Chu CQ, Feldmann M, Maim RN: Cytokine expression in rheumatoid arthritis. Br J Rheumatol 1991;30 (suppl 1):76-80.
3. Bedard PA, Golds EE: Cytokine-induced expression of mRNAs for chemotactic factors in human synovial cells and fibroblasts. J Cell Physiol 1993;154:433-41.
4. Oppenheim JJ, Zachariae CO, Mukaida N, Matsushima K: Properties of the novel proinflammatory supergene "intercrine" cytokine family Annu Rev Immunol 1991;9.617-18.
5. Pacifici R, Carano A, Santoro SA, et al.: Bone matrix constituents stimulate interleukin-1 release from human blood mononuclear cells. J Clin Invest 1991,87:221-8.
6. Schreck R, Baeuerle PA: A role for oxygen radicals as second messengers. Trend? Cell Biol 1991; 1:39-42.
7. Schreck R, Rieber P, Baeuerle PA: Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1 EMBO J 1991; 10:2247-58
8. Schulze-Osthoff K, Beyaert R, Vanhaesebroeck B. Haegeman G. Fiers W: Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene induction effects of TNF. EMBO J 1993, 12:3095-104
9. Mukaida N, Mahe Y. Matsushima K: Cooperative interaction of nuclear factor-kappa B and cis-regulatory enhancer binding proteinlike factor binding elements in activating the interleukin-8 gene by pro-inflammatory cytokines J Biol Chem 1990, 265:21128-33.
10. Miyazaki T, Sato M, Murata M, Maeda K, Seo H: Factor(s) present in serum from patients on long-term hemodialysis increase(s) mRNAs for collagenase and stromelysin in synovial cells. Am J Nephrol 1995:15-48-56.
11. Goldberg GI, Wilhelm SM, Kronbergcr A, Bauer EA, Grant GA. Eisen AZ: Human fibroblast collagenase: Complete primary structure and homology to an oncogene transformation-induced rat protein. J Biol Chem 1986;261:6600-5
12. Matsushima K, Morishita K. Yoshimura T. et al.; Molecular cloning of a human monocyte-derived neutrophil chemotactic factor (MDNCF) and the induction of MDNCF mRNA by interleukin 1 and tumor necrosis factor. J Exp Med 1988;167:1883-93.
13. Yoshimura T. Yuhki N, Moore SK, Appella E, Lerman MI. Leonard EJ: Human monocyte chemoattractant protein-1 (MCP-1): Full-length cDNA cloning, expression in mitogen-stimulated blood mononuclear leukocytes, and sequence similarity to mouse competence gene JE. FEBS Lett 1989;244 487-93.
14. Arcaii P, Martinelli R, Salvatore F: The complete sequence of a full length cDNA for human liver glyeeraldehyde-3-phosphate dehydrogenase: Evidence for multiple mRNA species Nucleic Acids Res 1984, 12:9179-89.
15. Chomczynski P. Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162.156-9.
16. Kambe F, Seo H. Murata Y. Matsui N Cloning of a complementary deoxynbonueleic acid coding for human thyroxine-binding globulin (TBG): Existence of two TBG messenger ribonuclcic acid species possessing different 3′-untranslated regions Mol Endocrinol 1988:2-181-5.
17. Osborn L, Kunkel S, Nabel GJ: Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B. Proc Natl Acad Sci USA 1959;86:2336-40.
18. Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principal of protein-dye binding. Anal Biochem 1976;72:248-54.
19. Stein B. Baldwin AJ: Distinct mechanisms for regulation of the interleukin-8 gene involve synergism and cooperativity between C/EBPand NF-kappa B Mol Cell Biol 1993;13:7191-8.
20. Nagaya T, Jameson JL; Distinct dimerization domains provide antagonist pathways for thyroid hormone receptor action. J Biol Chem 1993;268:24278-82.
21. Ida N, Sakurai S. Hosoi K, Kunitomo T: A highly sensitive enzyme-linked immunosorbent assay for the measurement of interlcukin-8 in biological fluids. J Immunol Methods 1992;156:27-38.
22. Meister A: Selective modification of glutathione metabolism Science 1983;220:472-7.
23. Aruoma OI, Halliwell B, Hoey BM, Butler J: The antioxidant action of N-acetytcysteine: Its reaction with hydrogen peroxide, hydroxyl radical, Superoxide, and hypochlorous acid. Free Radic Biol Med 1989;6:593-7.
24. Smilkstein MJ. Knapp GL, Kulig KW, Rumack BH: Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose: Analysis of the national multicenter study (1976 to 1985). N Eng J Med 1988;319:1557-62.
25. Anderson ME, Meister A: Intracellular delivery of cysteine. Methods Enzymol 1987;143.313-25.
26. Shyy YJ, Li YS, Kolattukudy PE: Structure of human monocyte chemotactic protein gene and its regulation by TPA. Biochem Biophys Res Commun 1990;169:346-51
27. Brenner DA, O'Hara M, Angel P. Chojkier M, Karin M: Prolonged activation of jun and collagenase genes by tumour necrosis factor-alpha. Nature 1989;337:661-3.
28. Amstad PA, Krupitza G, Cerutti PA: Mechanism of c-fos induction by active oxygen. Cancer Res 1992;52:3952-60.
29. Datta R, Hallahan DE, Kharbanda SM. et al.; Involvement of reactive oxygen intermediates in the induction of c-jun gene transcription by ionizing radiation. Biochemistry 1992;31:8300-6.
30. Xanthoudakis S. Curran T. Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity EMBO J 1992;11:653-65.
31. Xanthoudakis S, Miao G. Wand F, Pan VC, Curran T: Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme. EMBO J 1992;11:3323-35.
32. Mitomo K. Nakayama K, Fujimoto K, Sun X, Seki S, Yamamoto K: Two different redox systems regulate the DNA-binding activity of the p50 subunit of NF-κB in vitro. Gene 1994;145:197-203.