Correlated structural kinetics and retarded solvent dynamics at the metalloprotease active site

Nature Structural and Molecular Biology

Volumn 18, Issue 10, 2010, Pages 1102-1108

  Grossman, Moran ^a   Born, Benjamin ^b   Heyden, Matthias ^b   Tworowski, Dmitry ^a   Fields, Gregg B ^c,d   Sagi, Irit ^a   Havenith, Martina ^b  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b RUHR UNIVERSITY BOCHUM   (Germany)

^c UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^d TORREY PINES INSTITUTE FOR MOLECULAR STUDIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METAL ION; METALLOPROTEINASE; WATER; ZINC;

ARTICLE; CATALYSIS; CONTROLLED STUDY; CORRELATIONAL STUDY; ENZYME ACTIVE SITE; ENZYME INHIBITOR COMPLEX; ENZYME STRUCTURE; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; HUMAN; MOLECULAR DYNAMICS; POLARIZATION; PRIORITY JOURNAL; PROTEIN HYDROLYSIS; STRUCTURE ANALYSIS; TERAHERTZ SPECTROSCOPY; X RAY ABSORPTION SPECTROSCOPY;

CATALYTIC DOMAIN; HYDROLYSIS; KINETICS; METALLOPROTEASES; MOLECULAR DYNAMICS SIMULATION; SOLVENTS;

EID: 80054967217     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb.2120     Document Type: Article

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