A boronic-acid-based probe for fluorescence polarization assays with penicillin binding proteins and β-lactamases

Analytical Biochemistry

Volumn 420, Issue 1, 2012, Pages 41-47

  Inglis, Steven R ^a   Strieker, Matthias ^a   Rydzik, Anna M ^a   Dessen, Andréa ^b   Schofield, Christopher J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b INSTITUT DE BIOLOGIE STRUCTURALE   (France)

Author keywords

Antibiotic resistance; Boronic acid; Fluorescence polarization; Ligand binding assay; Penicillin binding protein; Lactamase

Indexed keywords

AMIDES; AMINO ACIDS; ANTIBIOTICS; CRYSTAL STRUCTURE; FLUORESCENCE; LIGANDS; POLARIZATION; PROTEINS; TRACERS;

ANTIBIOTIC RESISTANCE; BORONIC ACID; FLUORESCENCE POLARIZATION; LACTAMASES; LIGAND BINDING; PENICILLIN- BINDING PROTEINS;

ACID RESISTANCE;

BETA LACTAMASE; BORONIC ACID DERIVATIVE; PENICILLIN BINDING PROTEIN; SERINE;

ARTICLE; BINDING AFFINITY; CHEMICAL STRUCTURE; COVALENT BOND; CRYSTAL STRUCTURE; FLUORESCENCE POLARIZATION IMMUNOASSAY; MOLECULAR PROBE; NONHUMAN; PRIORITY JOURNAL; STREPTOCOCCUS PNEUMONIAE;

BACTERIA (MICROORGANISMS); STREPTOCOCCUS PNEUMONIAE;

EID: 80054956493     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2011.08.036     Document Type: Article

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