Trichloroethylene induces methylation of the Serca2 promoter in H9c2 cells and embryonic heart

Cardiovascular Toxicology

Volumn 11, Issue 3, 2011, Pages 204-214

  Palbykin, Brittany ^a   Borg, Jamie ^a   Caldwell, Patricia T ^a   Rowles, Josh ^a   Papoutsis, Andreas J ^a   Romagnolo, Donato F ^a   Selmin, Ornella I ^a  

^a UNIVERSITY OF ARIZONA   (United States)

Author keywords

Cardiac development; DNA methylation; Epigenetic; S adenosyl methionine; Serca2; Trichloroethylene

Indexed keywords

GENOMIC DNA; S ADENOSYLMETHIONINE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE 2; TRANSCRIPTION FACTOR SP1; TRICHLOROETHYLENE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARDIOTOXICITY; CHROMATIN IMMUNOPRECIPITATION; CONCENTRATION RESPONSE; CONSENSUS SEQUENCE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; DNA SEQUENCE; EMBRYO; EMBRYONAL TISSUE; EPIGENETICS; FEMALE; HEART DEVELOPMENT; HEART FUNCTION; MYOBLAST; NONHUMAN; NUCLEOTIDE SEQUENCE; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; RAT; TERATOGENICITY; TRANSCRIPTION REGULATION;

ANIMALS; BASE SEQUENCE; BINDING SITES; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; CPG ISLANDS; DNA METHYLATION; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GESTATIONAL AGE; HEART; MOLECULAR SEQUENCE DATA; MYOBLASTS, CARDIAC; MYOCYTES, CARDIAC; PROMOTER REGIONS, GENETIC; RATS; RATS, SPRAGUE-DAWLEY; S-ADENOSYLMETHIONINE; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; SOLVENTS; SP1 TRANSCRIPTION FACTOR; TIME FACTORS; TRICHLOROETHYLENE;

ANIMALIA; RATTUS;

EID: 80054930663     PISSN: 15307905     EISSN: 15590259     Source Type: Journal    
DOI: 10.1007/s12012-011-9113-3     Document Type: Article

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