Effect of trichloroethylene on DNA methylation and expression of early-intermediate protooncogenes in the liver of B6C3F1 mice

Journal of Biochemical and Molecular Toxicology

Volumn 13, Issue 5, 1999, Pages 231-237

  Tao, Lianhui ^a   Ge, Rongrong ^a   Xie, Mi ^a   Kramer, Paula M ^a   Pereira, Michael A ^a  

^a MEDICAL COLLEGE OF OHIO   (United States)

Author keywords

DNA Methylation; Mouse Liver Carcinogens; mRNA Expression; Protooncogene; Trichloroethylcne

Indexed keywords

DNA; IMMEDIATE EARLY PROTEIN; MESSENGER RNA; MYC PROTEIN; ONCOPROTEIN; PROTEIN C JUN; SOLVENT; TRICHLOROETHYLENE;

ANIMAL; ARTICLE; BIOSYNTHESIS; DNA METHYLATION; DRUG EFFECT; FEMALE; GENE EXPRESSION; GENETICS; LIVER; METABOLISM; MOUSE; MOUSE STRAIN; NORTHERN BLOTTING; POLLUTANT; SOUTHERN BLOTTING;

ANIMALS; BLOTTING, NORTHERN; BLOTTING, SOUTHERN; DNA; DNA METHYLATION; ENVIRONMENTAL POLLUTANTS; FEMALE; GENE EXPRESSION; IMMEDIATE-EARLY PROTEINS; LIVER; MICE; MICE, INBRED STRAINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-JUN; PROTO-ONCOGENE PROTEINS C-MYC; RNA, MESSENGER; SOLVENTS; TRICHLOROETHYLENE;

EID: 0032616340     PISSN: 10956670     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1099-0461(1999)13:5<231::aid-jbt2>3.3.co;2-6     Document Type: Article

References (19)

1. International Agency for Research on Cancer (IARC). Trichloroethylene. In IARC monograph on the evaluation of the carcinogenic risk of chemicals to human. Volume 63. Lyon, France: International Agency for Research on Cancer; 1995. p 75-158.
2. National Cancer Institute (NCI). Carcinogenesis bioassay of trichloroethylene. Washington, D.C.; National Cancer Institute; 1976. CAS No. 79-01-6 NCI-CG-TR-2.
3. Fukuda K, Takemoto K, Tsuruta H. Inhalation carcinogenicity of trichloroethylene in mice and rats. Ind Health 1983;21:243-252.
4. National Toxicology Program (NTP). Carcinogenesis bioassay of trichloroethylene (without epichlorohydrin) in F344/N rats and B6C3F1/N mice (gavage studies). Washington, D.C.: U.S. Department of Health and Human Services; 1983. Technical report 243. NIH Publ. No. 83-1799.
5. National Toxicology Program (NTP). Toxicology and carcinogenesis studies of trichloroethylene in four strains of rats (ACI, Marshell, Osborne-Mendel). Bethesda, MD: U.S. Department of Health and Human Services; 1988. NTP TR 273, NIH Publ. No. 88-2529.
6. National Toxicology Program (NTP). Carcinogenesis studies of trichloroethylene in F344/N rats and B6C3F1 mice. Bethesda, MD: U.S. Department of Health and Human Services; 1990. NTP technical report No. 243.
7. Gulati D, Sabharwal, P, Shelby M. Tests for the induction of chromosomal aberrations and sister chromatic exchanges in cultured Chinese hamster ovary (CHO) cells. In: Ashby J, deSerres F, Draper M, Ishidate Jr J, Margolin B, Matter B, Shelby M, editors. Evaluation of short-term tests for carcinogens. Amsterdam: Elsevier Science Publisher; 1985. p 413-426.
8. Yoon J, Mason J, Valencia R, Woodruff R, Zimmering S. Chemical mutagenesis testing in Drosophila. IV. Results of 45 coded compounds tested for the National Toxicology Program. Environ Mutagen, 1985;7:349-367.
9. Mortelmans K, Hawarth S, Lawlor T, Speck W, Tainer B, Zeiger E. Salmonella mutagenicity tests: II. Results from testing of 270 chemicals. Environ Mutagen 1986;8 Suppl 7:1-119.
10. Bruckner JV, Davis BD, Blancato JN. Metabolism, toxicity, and carcinogenicity of trichloroethylene. CRC Crit Rev Toxicol 1989;20:31-50.
11. Fahrig R, Madle S, Baumann H. Genetic toxicology of trichloroethylene (TCE). Mutation Res 1995;340:1-36.
12. Anna CH, Maronpot RR, Pereira MA, Foley JF, Malarkey DE, Anderson MW. Ras proto-oncogene activation in dichloroacetic acid-, trichloroethylene- and tetrachloro-ethylene-induced liver tumors in B6C3F1 mice. Carcinogenesis 1994;15:2255-2261.
13. Butterworth BE, Popp JA, Conolly RB, Goldsvvorthy TL. Chemically induced cell proliferation in Carcinogenesis. IARC Scient Publ 1992;116:279-305.
14. Goodman JI, Ward JM, Popp JA, Klauning JE, Fox TR. Mouse liver Carcinogenesis: mechanisms and relevance. Fundam Appl Toxicol 1991;17:651-665.
15. Roberts RA, Nebert DW, Hickman JA, Richburg JH, Goldsworthy TL. Perturbation of the mitosis/apoptosis balance: a fundamental mechanism in toxicology (review). Fundam Appl Toxicol 1997;38(2):107-115.
16. Elcombe CR, Rose MS, Pratt IS. Biochemical, histological and ultrastructural changes in rat and mouse liver following the administration of trichloroethylene: possible relevance to species differences in hepatocarcinogenicity. Toxicol Appl Pharmacol 1985;79:365-373.
17. Sæter G, Seglen PO. Cell biology of hepatocarcinogenesis. Crit Rev Oncogen 1990;1:437-466.
18. Fausto N, Webber EM. Control of liver growth. Crit Rev Eukaryotic Gene Expression 1993;3:117-135.
19. Fausto N, Shank PR. Oncogene expression in liver regeneration and hepatocarcinogenesis. Hepatology 1983;3:1016-1023.