Hematopoietic derived cell infiltration of the intestinal tumor microenvironment in ApcMin/+ mice

Microscopy and Microanalysis

Volumn 17, Issue 4, 2011, Pages 528-539

  Davis, Celestia ^a   Price, Robert ^a,b   Acharya, Grishma ^a   Baudino, Troy ^b,c   Borg, Thomas ^b   Berger, Franklin G ^a   Peña, Maria Marjorette O ^a  

^a UNIVERSITY OF SOUTH CAROLINA   (United States)

^b UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c TEXAS A M COLLEGE OF MEDICINE   (United States)

Author keywords

ApcMin + mice; bone marrow derived cells; colon cancer; hematopoietic stem cells; tumor microenvironment

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN; GREEN FLUORESCENT PROTEIN; OSTEOPONTIN;

ADENOMA; ANIMAL; ARTICLE; BIOSYNTHESIS; BONE MARROW TRANSPLANTATION; CYTOLOGY; FLUORESCENCE MICROSCOPY; GENETICS; HEMATOPOIETIC SYSTEM; INTESTINE; INTESTINE TUMOR; METABOLISM; METHODOLOGY; MOUSE; PATHOLOGY; STAINING; TUMOR MICROENVIRONMENT;

ADENOMA; ANIMALS; BONE MARROW TRANSPLANTATION; GREEN FLUORESCENT PROTEINS; HEMATOPOIETIC SYSTEM; INTESTINAL NEOPLASMS; INTESTINES; MICE; MICROSCOPY, FLUORESCENCE; OSTEOPONTIN; STAINING AND LABELING; TUMOR MICROENVIRONMENT;

MUS;

EID: 80054911916     PISSN: 14319276     EISSN: 14358115     Source Type: Journal    
DOI: 10.1017/S1431927611000043     Document Type: Article

References (54)

1. American Cancer Society (2009). Colorectal Cancer Facts and Figures 2008-2010. Atlanta, GA: American Cancer Society.
2. Berger, S.H., Davis, S.T., Barbour, K.W. & Berger, F.G. (1988). The role of thymidylate synthase in the response to fluoropyrimidine-folinic acid combinations. Adv Exp Med Biol 244, 59-69.
3. Chantrain, C.F., Feron, O., Marbaix, E. & Declerck, Y.A. (2008). Bone marrow microenvironment and tumor progression. Cancer Microenviron 1, 23-35.
4. Chau, I. & Cunningham, D. (2006). Adjuvant therapy in colon cancer-What, when and how? Ann Oncol 17, 1347-1359. (Pubitemid 44400373)
5. Chen, L.C., Hao, C.Y., Chiu, Y.S., Wong, P., Melnick, J.S., Brot-man, M., Moretto, J., Mendes, F., Smith, A.P., Bennington, J.L., Moore, D. & Lee, N.M. (2004). Alteration of gene expression in normal-appearing colon mucosa of APC(min) mice and human cancer patients. Cancer Res 64, 3694-3700. (Pubitemid 38657950)
6. Coussens, L.M. & Werb, Z. (2001). Inflammatory cells and cancer: Think different! JExp Med 193, F23-F26. (Pubitemid 32524459)
7. Coussens, L.M. & Werb, Z. (2002). Inflammation and cancer. Nature 420, 860-867. (Pubitemid 36019639)
8. Danenberg, P.V. (1977). Thymidylate synthetase-A target enzyme in cancer chemotherapy. Biochim Biophys Acta 473, 73-92. (Pubitemid 8238357)
9. Denhardt, D.T. & Noda, M. (1998). Osteopontin expression and function: Role in bone remodeling. J Cell Biochem Suppl 30-31, 92-102. (Pubitemid 29028730)
10. Denhardt, D.T., Noda, M., O'Regan, A.W., Pavlin, D. & Ber-man, J.S. (2001). Osteopontin as a means to cope with environmental insults: Regulation of inflammation, tissue remodeling, and cell survival. J Clin Invest 107, 1055-1061. (Pubitemid 32422899)
11. Erdman, S.E., Rao, V.P., Poutahidis, T., Ihrig, M.M., Ge, Z., Feng, Y., Tomczak, M., Rogers, A.B., Horwitz, B.H. & Fox, J.G. (2003).CD4(+)CD25(+) regulatory lymphocytes require interleukin 10 to interrupt colon carcinogenesis in mice. Cancer Res 63, 6042-6050. (Pubitemid 37187508)
12. Erdman, S.E., Sohn, J.J., Rao, V.P., Nambiar, P.R., Ge, Z., Fox, J.G. & Schauer, D.B. (2005).CD4+CD25+ regulatory lymphocytes induce regression of intestinal tumors in ApcMin/+ mice. Cancer Res 65, 3998-4004. (Pubitemid 40775635)
13. Federsppiel, B., Melhado, I.G., Duncan, A.M., Delaney, A., Schappert, K., Clark-Lewis, I. & Jirik, F.R. (1993). Molecular cloning of the cDNA and chromosomal localization of the gene for a putative seven-transmembrane segment (7-TMS) receptor isolated from human spleen. Genomics 16, 707-712. (Pubitemid 23183492)
14. Ferrari, N., Glod, J., Lee, J., Kobiler, D. & Fine, H.A. (2003). Bone marrow-derived, endothelial progenitor-like cells as angiogenesis-selective gene-targeting vectors. Gene Ther 10, 647-656. (Pubitemid 36553610)
15. Fodde, R., Kuipers, J., Rosenberg, C., Smits, R., Kielman, M., Gaspar, C., Van Es, J.H., Breukel, C., Wiegant, J., Giles, R.H. & Clevers, H. (2001). Mutations in the APC tumour suppressor gene cause chromosomal instability. Nat Cell Biol 3, 433-438. (Pubitemid 32288454)
16. Fuseler, J.W., Bedenbaugh, A., Yekkala, K. & Baudino, T.A. (2010). Fractal and image analysis of the microvasculature in normal intestinal submucosa and intestinal polyps in Apc(Min/+) mice. Microsc Microanal 16, 73-79.
17. Gallagher, P.G., Bao, Y., Prorock, A., Zigrino, P., Nischt, R., Politi, V., Mauch, C., Dragulev, B. & Fox, J.W. (2005).Gene expression profiling reveals cross-talk between melanoma and fibroblasts: Implications for host-tumor interactions in metastasis. Cancer Res 65, 4134-4146. (Pubitemid 40775651)
18. Galli, S.J., Nakae, S. & Tsai, M. (2005). Mast cells in the development of adaptive immune responses. Nat Immunol 6, 135-142. (Pubitemid 40268194)
19. Galon, J., Costes, A., Sanchez-Cabo, F., Kirilovsky, A., Mlec-nik, B., Lagorce-Pages, C., Tosolini, M., Camus, M., Berger, A., Wind, P., Zinzindohoue, F., Bruneval, P., Cugnenc, P.H., Trajanoski, Z., Fridman, W.H. & Pages, F. (2006).Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science 313, 1960-1964. (Pubitemid 44498003)
20. Gounaris, E., Blatner, N.R., Dennis, K., Magnusson, F., Gur-ish, M.F., Strom, T.B., Beckhove, P., Gounari, F. & Khazaie, K. (2009). T-regulatory cells shift from a protective anti-inflammatory to a cancer-promoting proinflammatory pheno-type in polyposis. Cancer Res 69, 5490-5497.
21. Gounaris, E., Erdman, S.E., Restaino, C., Gurish, M.F., Friend, D.S., Gounari, F., Lee, D.M., Zhang, G., Glickman, J.N., Shin, K., Rao, V.P., Poutahidis, T., Weissleder, R., Mc-Nagny, K.M. & Khazaie, K. (2007). Mast cells are an essential hematopoietic component for polyp development. Proc Natl Acad Sci USA 104, 19977-19982.
22. Hall, B.M., Fortney, J.E., Taylor, L., Wood, H., Wang, L., Adams, S., Davis, S. & Gibson, L.F. (2004). Stromal cells expressing elevated VCAM-1 enhance survival of B lineage tumor cells. Cancer Lett 207, 229-239. (Pubitemid 38457045)
23. Hanna, E., Quick, J. & Libutti, S.K. (2009). The tumour micro-environment: A novel target for cancer therapy. Oral Dis 15, 8-17.
24. Hofmeister, V., Schrama, D. & Becker, J.C. (2008). Anti-cancer therapies targeting the tumor stroma. Cancer Immunol Immu-nother 57, 1-17. (Pubitemid 350043655)
25. Jenq, R.R. & van den Brink, M.R. (2010). Allogeneic haematopoietic stem cell transplantation: Individualized stem cell and immune therapy of cancer. Nat Rev Cancer 10, 213-221.
26. Jin, D.K., Shido, K., Kopp, H.G., Petit, I., Shmelkov, S.V., Young, L.M., Hooper, A.T., Amano, H., Avecilla, S.T., Heissig, B., Hattori, K., Zhang, F., Hicklin, D.J., Wu, Y., Zhu, Z., Dunn, A., Salari, H., Werb, Z., Hackett, N.R., Crystal, R.G., Lyden, D. & Rafii, S. (2006). Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4+ hemangiocytes. Nat Med 12, 557-567.
27. Kettunen, H.L., Kettunen, A.S. & Rautonen, N.E. (2003). Intestinal immune responses in wild-type and Apcmin/+ mouse, a model for colon cancer. Cancer Res 63, 5136-5142. (Pubitemid 37022655)
28. Kinzler, K.W. & Vogelstein, B. (1996). Lessons from hereditary colorectal cancer. Cell 87, 159-170. (Pubitemid 26358996)
29. Kitahara, O., Furukawa, Y., Tanaka, T., Kihara, C., Ono, K., Yanagawa, R., Nita, M.E., Takagi, T., Nakamura, Y. & Tsunoda, T. (2001). Alterations of gene expression during colorectal carcinogenesis revealed by cDNA microarrays after laser-capture microdissection of tumor tissues and normal epithelia. Cancer Res 61, 3544-3549. (Pubitemid 32694957)
30. Lin, E.Y., Nguyen, A.V., Russell, R.G. & Pollard, J.W. (2001). Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy. JExp Med 193, 727-740.
31. Littlepage, L.E., Egeblad, M. & Werb, Z. (2005). Coevolution of cancer and stromal cellular responses. Cancer Cell 7, 499-500. (Pubitemid 40799241)
32. Longley, D.B., Harkin, D.P. & Johnston, P.G. (2003). 5-Fluorouracil: Mechanisms of action and clinical strategies. Nat Rev Cancer 3, 330-338. (Pubitemid 37328853)
33. Masuya, M., Drake, C.J., Fleming, P.A., Reilly, C.M., Zeng, H., Hill, W.D., Martin-Studdard, A., Hess, D.C. & Ogawa, M. (2003). Hematopoietic origin of glomerular mesangial cells. Blood 101, 2215-2218. (Pubitemid 36302060)
34. Moser, A.R., Dove, W.F., Roth, K.A. & Gordon, J.I. (1992). The Min (multiple intestinal neoplasia) mutation: Its effect on gut epithelial cell differentiation and interaction with a modifier system. J Cell Biol 116, 1517-1526.
35. Moser, A.R., Pitot, H.C. & Dove, W.F. (1990). A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science 247, 322-324.
36. Muller, A., Homey, B., Soto, H., Ge, N., Catron, D., Buchanan, M.E., McClanahan, T., Murphy, E., Yuan, W., Wagner, S.N., Barrera, J.L., Mohar, A., Verastegui, E. & Zlotnik, A. (2001 ). Involvement of chemokine receptors in breast cancer metastasis. Nature 410, 50-56. (Pubitemid 32225831)
37. Nicolella, D., Maione, P. & Gridelli, C. (2003). Targeted therapies: Focus on a new strategy for gastrointestinal tumors. Crit Rev Oncol Hematol 47, 261-271. (Pubitemid 37074856)
38. Obermueller, E., Vosseler, S., Fusenig, N.E. & Mueller, M.M. (2004). Cooperative autocrine and paracrine functions of gran-ulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor in the progression of skin carcinoma cells. Cancer Res 64, 7801-7812. (Pubitemid 39446913)
39. Orimo, A. & Weinberg, R.A. (2006). Stromal fibroblasts in cancer: A novel tumor-promoting cell type. Cell Cycle 5, 1597-1601. (Pubitemid 44285243)
40. Papaspyridonos, M. & Lyden, D. (2008). Chapter 11. The role of bone marrow-derived cells in tumor angiogenesis and metasta-tic progression. Methods Enzymol 444, 255-269.
41. Pietras, K., Rubin, K., Sjoblom, T., Buchdunger, E., Sjoquist, M., Heldin, C.H. & Ostman, A. (2002). Inhibition of PDGF receptor signaling in tumor stroma enhances antitumor effect of chemotherapy. Cancer Res 62, 5476-5484.
42. Purhonen, S., Palm, J., Rossi, D., Kaskenpaa, N., Rajantie, I., Yla-Herttuala, S., Alitalo, K., Weissman, I.L. & Salven, P. (2008). Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growth. ProcNatlAcad Sci USA 105, 6620-6625. (Pubitemid 351754556)
43. Rafii, S., Lyden, D., Benezra, R., Hattori, K. & Heissig, B. (2002). Vascular and haematopoietic stem cells: Novel targets for anti-angiogenesis therapy? Nat Rev Cancer 2, 826-835. (Pubitemid 37328901)
44. Rizvi, A.Z., Swain, J.R., Davies, P.S., Bailey, A.S., Decker, A.D., Willenbring, H., Grompe, M., Fleming, W.H. & Wong, M.H. (2006). Bone marrow-derived cells fuse with normal and transformed intestinal stem cells. Proc Natl Acad Sci USA 103, 6321-6325.
45. Roorda, B.D., Ter Elst, A., Kamps, W.A. & De Bont, E.S. (2009). Bone marrow-derived cells and tumor growth: Contribution of bone marrow-derived cells to tumor micro-environments with special focus on mesenchymal stem cells. Crit Rev Oncol Hema-tol 69, 187-198.
46. Salvucci, O., Basik, M., Yao, L., Bianchi, R. & Tosato, G. (2004). Evidence for the involvement of SDF-1 and CXCR4 in the disruption of endothelial cell-branching morphogenesis and angiogenesis by TNF-alpha and IFN-gamma. JLeukoc Biol 76, 217-226. (Pubitemid 38857190)
47. Schwarz, Y.X., Yang, M., Qin, D., Wu, J., Jarvis, W.D., Grant, S., Burton, G.F., Szakal, A.K. & Tew, J.G. (1999). Follicular dendritic cells protect malignant B cells from apoptosis induced by anti-Fas and antineoplastic agents. J Immunol 163, 6442-6447.
48. Shoemaker, A.R., Gould, K.A., Luongo, C., Moser, A.R. & Dove, W.F. (1997). Studies of neoplasia in the Min mouse. Biochim Biophys Acta 1332, F25-F48. (Pubitemid 27211615)
49. Sugiyama, Y., Farrow, B., Murillo, C., Li, J., Watanabe, H., Sugiyama, K. & Evers, B.M. (2005). Analysis of differential gene expression patterns in colon cancer and cancer stroma using microdissected tissues. Gastroenterology 128, 480-486. (Pubitemid 40431099)
50. Vincent, J., Mignot, G., Chalmin, F., Ladoire, S., Bruchard, M., Chevriaux, A., Martin, F., Apetoh, L., Rebe, C. & Ghiringhelli, F. (2010). 5-Fluorouracil selectively kills tumor-associated myeloid-derived suppressor cells resulting in enhanced T cell-dependent antitumor immunity. Cancer Res 70, 3052-3061.
51. Wang, L., Chen, L., Benincosa, J., Fortney, J. & Gibson, L.F. (2005). VEGF-induced phosphorylation of Bcl-2 influences B lineage leukemic cell response to apoptotic stimuli. Leukemia 19, 344-353. (Pubitemid 40403309)
52. Wang, L., Fortney, J.E. & Gibson, L.F. (2004).Stromal cell protection of B-lineage acute lymphoblastic leukemic cells during chemotherapy requires active Akt. Leuk Res 28, 733-742. (Pubitemid 38639741)
53. Weaver, V.M., Lelievre, S., Lakins, J.N., Chrenek, M.A., Jones, J.C., Giancotti, F., Werb, Z. & Bissell, M.J. (2002). Beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium. Cancer Cell 2, 205-216. (Pubitemid 41043976)
54. Yang, L., Huang, J., Ren, X., Gorska, A.E., Chytil, A., Aakre, M., Carbone, D.P., Matrisian, L.M., Richmond, A., Lin, P.C. & Moses, H.L. (2008). Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis. Cancer Cell 13, 23-35. (Pubitemid 350309741)