메뉴 건너뛰기




Volumn 1, Issue 2, 2011, Pages 175-183

Mitochondrial dysfunction in skin fibroblasts from a Parkinson's disease patient with an alpha-synuclein triplication

Author keywords

fibroblasts; mitochondrial dysfunction; Parkinson's disease; SNCA triplication

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALPHA SYNUCLEIN; PARAQUAT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SMALL INTERFERING RNA;

EID: 80054873779     PISSN: 18777171     EISSN: 1877718X     Source Type: Journal    
DOI: 10.3233/JPD-2011-11025     Document Type: Article
Times cited : (25)

References (36)
  • 3
    • 71949090833 scopus 로고    scopus 로고
    • Mitochondrial trafficking of APP and alpha synuclein: Relevance to mitochondrial dysfunction in alzheimers and Parkinson's diseases
    • Devi L & Anandatheerthavarada HK (2010) Mitochondrial trafficking of APP and alpha synuclein: Relevance to mitochondrial dysfunction in Alzheimers and Parkinson's diseases. Biochim Biophys Acta, 1802, 11-19.
    • (2010) Biochim. Biophys. Acta. , vol.1802 , pp. 11-19
    • Devi, L.1    Anandatheerthavarada, H.K.2
  • 4
    • 44049099669 scopus 로고    scopus 로고
    • Mitochondrial import and accumulation of alpha-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain
    • Devi L, Raghavendran V, Prabhu BM, Avadhani NG & Anandatheerthavarada HK (2008) Mitochondrial import and accumulation of alpha-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain. J Biol Chem, 283, 9089-9100.
    • (2008) J. Biol. Chem. , vol.283 , pp. 9089-9100
    • Devi, L.1    Raghavendran, V.2    Prabhu, B.M.3    Avadhani, N.G.4    Anandatheerthavarada, H.K.5
  • 5
    • 57049151865 scopus 로고    scopus 로고
    • Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions
    • McFarland MA, Ellis CE, Markey SP&Nussbaum RL (2008) Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions. Mol Cell Proteomics, 7, 2123-2137.
    • (2008) Mol. Cell Proteomics. , vol.7 , pp. 2123-2137
    • McFarland, M.A.1    Ellis, C.E.2    Markey, S.P.3    Nussbaum, R.L.4
  • 6
    • 78049383132 scopus 로고    scopus 로고
    • Mitochondrial alpha-synuclein accumulation impairs complex I function in dopaminergic neurons and results in increased mitophagy in vivo
    • Chinta SJ, Mallajosyula JK, Rane A & Andersen JK (2010) Mitochondrial alpha-synuclein accumulation impairs complex I function in dopaminergic neurons and results in increased mitophagy in vivo. Neurosci Lett, 486, 235-239.
    • (2010) Neurosci. Lett. , vol.486 , pp. 235-239
    • Chinta, S.J.1    Mallajosyula, J.K.2    Rane, A.3    Andersen, J.K.4
  • 10
    • 68949151944 scopus 로고    scopus 로고
    • α-synuclein overexpression and aggregation exacerbates impairment of mitochondrial functions by augmenting oxidative stress in human neuroblastoma cells
    • Parihar MS, Parihar A, Fujita M, Hashimoto M & Ghafourifar P (2009) Alpha-synuclein overexpression and aggregation exacerbates impairment of mitochondrial functions by augmenting oxidative stress in human neuroblastoma cells. Int J Biochem Cell Biol, 41, 2015-2024.
    • (2009) Int. J. Biochem. Cell Biol. , vol.41 , pp. 2015-2024
    • Parihar, M.S.1    Parihar, A.2    Fujita, M.3    Hashimoto, M.4    Ghafourifar, P.5
  • 11
    • 44649150145 scopus 로고    scopus 로고
    • Mitochondrial localization of alpha-synuclein protein in alpha-synuclein overexpressing cells
    • Shavali S, Brown-Borg HM, Ebadi M & Porter J (2008) Mitochondrial localization of alpha-synuclein protein in alpha-synuclein overexpressing cells. Neurosci Lett, 439, 125-128.
    • (2008) Neurosci. Lett. , vol.439 , pp. 125-128
    • Shavali, S.1    Brown-Borg, H.M.2    Ebadi, M.3    Porter, J.4
  • 12
    • 34748826792 scopus 로고    scopus 로고
    • Localization of α-synuclein to mitochondria within midbrain of mice
    • DOI 10.1097/WNR.0b013e3282f03db4, PII 0000175620071008000007
    • Li WW, Yang R, Guo JC, Ren HM, Zha XL, Cheng JS & Cai DF (2007) Localization of alpha-synuclein to mitochondria within midbrain of mice. Neuroreport, 18, 1543-1546. (Pubitemid 47476380)
    • (2007) NeuroReport , vol.18 , Issue.15 , pp. 1543-1546
    • Li, W.-W.1    Yang, R.2    Guo, J.-C.3    Ren, H.-M.4    Zha, X.-L.5    Cheng, J.-S.6    Cai, D.-F.7
  • 13
    • 0037087598 scopus 로고    scopus 로고
    • Punch biopsy of the skin
    • Zuber TJ (2002) Punch biopsy of the skin. Am FamPhysician, 65, 1155-1158.
    • (2002) Am. Fam. Physician , vol.65 , pp. 1155-1158
    • Zuber, T.J.1
  • 14
    • 0036670612 scopus 로고    scopus 로고
    • Development of a high throughput screening assay for mitochondrial membrane potential in living cells
    • Huang SG (2002) Development of a high throughput screening assay for mitochondrial membrane potential in living cells. J Biomol Screen, 7, 383-389.
    • (2002) J. Biomol. Screen , vol.7 , pp. 383-389
    • Huang, S.G.1
  • 15
    • 68549136513 scopus 로고    scopus 로고
    • Differential effects of PINK1 nonsense and missense mutations on mitochondrial function and morphology
    • Grunewald A, Gegg ME, Taanman JW, King RH, Kock N, Klein C & Schapira AH (2009) Differential effects of PINK1 nonsense and missense mutations on mitochondrial function and morphology. Exp Neurol, 219, 266-273.
    • (2009) Exp. Neurol. , vol.219 , pp. 266-273
    • Grunewald, A.1    Gegg, M.E.2    Taanman, J.W.3    King, R.H.4    Kock, N.5    Klein, C.6    Schapira, A.H.7
  • 18
    • 2342530852 scopus 로고    scopus 로고
    • Quantitative PCR analysis of mitochondrial DNA content in patients with mitochondrial disease
    • Bai RK, Perng CL, Hsu CH, Wong LJ (2004) Quantitative PCR analysis of mitochondrial DNA content in patients with mitochondrial disease. Ann N Y Acad Sci 1011, 304-309.
    • (2004) Ann. N. Y. Acad. Sci. , vol.1011 , pp. 304-309
    • Bai, R.K.1    Perng, C.L.2    Hsu, C.H.3    Wong, L.J.4
  • 19
    • 0028127866 scopus 로고
    • Autosomal dominant Lewy body Parkinsonism in a four-generation family
    • Waters CH & Miller CA (1994) Autosomal dominant Lewy body Parkinsonism in a four-generation family. Ann Neurol, 35, 59-64. (Pubitemid 24027607)
    • (1994) Annals of Neurology , vol.35 , Issue.1 , pp. 59-64
    • Waters, C.H.1    Miller, C.A.2
  • 21
    • 37049004489 scopus 로고    scopus 로고
    • Mitochondria in the aetiology and pathogenesis of Parkinson's disease
    • DOI 10.1016/S1474-4422(07)70327-7, PII S1474442207703277
    • Schapira AH (2008) Mitochondria in the aetiology and pathogenesis of Parkinson's disease. Lancet Neurol, 7, 97-109. (Pubitemid 350251942)
    • (2008) The Lancet Neurology , vol.7 , Issue.1 , pp. 97-109
    • Schapira, A.H.1
  • 22
    • 55849122639 scopus 로고    scopus 로고
    • Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis
    • Henchcliffe C & Beal MF (2008) Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis. Nat Clin Pract Neurol, 4, 600-609.
    • (2008) Nat. Clin Pract. Neurol. , vol.4 , pp. 600-609
    • Henchcliffe, C.1    Beal, M.F.2
  • 23
    • 0036793929 scopus 로고    scopus 로고
    • Mechanistic approaches to Parkinson's disease pathogenesis
    • Betarbet R, Sherer TB, Di Monte DA & Greenamyre JT (2002) Mechanistic approaches to Parkinson's disease pathogenesis. Brain Pathol, 12, 499-510. (Pubitemid 35154938)
    • (2002) Brain Pathology , vol.12 , Issue.4 , pp. 499-510
    • Betarbet, R.1    Sherer, T.B.2    Di Monte, D.A.3    Greenamyre, J.T.4
  • 24
    • 34548400209 scopus 로고    scopus 로고
    • Model fusion the next phase in developing animal models for Parkinson's disease
    • Manning-Bog AB & Langston JW (2007) Model fusion, the next phase in developing animal models for Parkinson's disease. Neurotox Res, 11, 219-240.
    • (2007) Neurotox. Res. , vol.11 , pp. 219-240
    • Manning-Bog, A.B.1    Langston, J.W.2
  • 26
    • 41749104745 scopus 로고    scopus 로고
    • Complex I deficiency in Parkinson's disease frontal cortex
    • DOI 10.1016/j.brainres.2007.10.061, PII S0006899307025814
    • Parker WD, Jr, Parks JK & Swerdlow RH (2008) Complex I deficiency in Parkinson's disease frontal cortex. Brain Res, 1189, 215-218. (Pubitemid 351842538)
    • (2008) Brain Research , vol.1189 , Issue.1 , pp. 215-218
    • Parker Jr., W.D.1    Parks, J.K.2    Swerdlow, R.H.3
  • 27
    • 0029050583 scopus 로고
    • Low platelet mitochondrial complex I and complex II/III activity in early untreated Parkinson's disease
    • Haas RH, Nasirian F, Nakano K, Ward D, Pay M, Hill R & Shults CW (1995) Low platelet mitochondrial complex I and complex II/III activity in early untreated Parkinson's disease. Ann Neurol, 37, 714-722.
    • (1995) Ann. Neurol. , vol.37 , pp. 714-722
    • Haas, R.H.1    Nasirian, F.2    Nakano, K.3    Ward, D.4    Pay, M.5    Hill, R.6    Shults, C.W.7
  • 30
    • 28844448703 scopus 로고    scopus 로고
    • The bipyridyl herbicide paraquat produces oxidative stress-mediated toxicity in human neuroblastoma SH-SY5Y cells: Relevance to the dopaminergic pathogenesis
    • DOI 10.1080/15287390500226987
    • Yang W & Tiffany-Castiglioni E (2005) The bipyridyl herbicide paraquat produces oxidative stress-mediated toxicity in human neuroblastoma SH-SY5Y cells: Relevance to the dopaminergic pathogenesis. J Toxicol Environ Health A, 68, 1939-1961. (Pubitemid 41765788)
    • (2005) Journal of Toxicology and Environmental Health - Part A , vol.68 , Issue.22 , pp. 1939-1961
    • Yang, W.1    Tiffany-Castiglioni, E.2
  • 32
    • 38949123181 scopus 로고    scopus 로고
    • Paraquat-induced apoptosis in human neuroblastoma SH-SY5Y cells: Involvement of p53 and mitochondria
    • Yang W & Tiffany-Castiglioni E (2008) Paraquat-induced apoptosis in human neuroblastoma SH-SY5Y cells: Involvement of p53 and mitochondria. J Toxicol Environ Health A, 71, 289-299.
    • (2008) J. Toxicol. Environ. Health A , vol.71 , pp. 289-299
    • Yang, W.1    Tiffany-Castiglioni, E.2
  • 34
    • 0037127197 scopus 로고    scopus 로고
    • The herbicide paraquat causes up-regulation and aggregation of α-synuclein in mice: Paraquat and α-synuclein
    • DOI 10.1074/jbc.C100560200
    • Manning-Bog AB, McCormack AL, Li J, Uversky VN, Fink AL & Di Monte DA (2002) The herbicide Paraquat causes up-regulation and aggregation of alpha-synuclein in mice: paraquat and alpha-synuclein. J Biol Chem, 277, 1641-1644. (Pubitemid 34968732)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.3 , pp. 1641-1644
    • Manning-Bog, A.B.1    McCormack, A.L.2    Li, J.3    Uversky, V.N.4    Fink, A.L.5    Di Monte, D.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.