Caenorhabditis elegans UCP4 protein controls complex II-mediated oxidative phosphorylation through succinate transport

Journal of Biological Chemistry

Volumn 286, Issue 43, 2011, Pages 37712-37720

  Pfeiffer, Matthew ^a   Kayzer, Ernst Bernhard ^c   Yang, Xianmei ^b   Abramson, Ellen ^a   Kenaston, M Alexander ^a   Lago, Cory U ^a,e   Lo, Herng Hsiang ^a   Sedensky, Margaret M ^c   Lunceford, Adam ^d   Clarke, Catherine F ^d   Wu, Sarah J ^a   McLeod, Chris ^f   Finkel, Toren ^e   Morgan, Philip G ^c   Mills, Edward M ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b FUDAN UNIVERSITY   (China)

^c SEATTLE CHILDREN S RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^f MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAENORHABDITIS ELEGANS; ELECTRON TRANSPORT CHAIN; GENETICALLY MODIFIED; IN-VIVO; INSULIN SIGNALING; KNOCKOUT MUTANT; LIFE SPAN; NOVEL FUNCTIONS; ORTHOLOGS; OVERLAPPING EXPRESSION; OXIDANT PRODUCTION; OXIDATIVE PHOSPHORYLATION; UNCOUPLING PROTEINS; WILD TYPES;

METABOLISM; OXIDANTS; PHOSPHORYLATION; PHYSIOLOGY;

MITOCHONDRIA;

SUCCINIC ACID; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN; UNCOUPLING PROTEIN 4;

ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DNA MODIFICATION; ELECTRON TRANSPORT; GENE FUNCTION; GENETICS; IN VIVO STUDY; LETHAL GENE; METABOLISM; MEV1 GENE; MITOCHONDRIAL GENE; MITOCHONDRIAL PERMEABILITY; MITOCHONDRIAL RESPIRATION; NEMATODE; NONHUMAN; NUCLEAR IMPORT; OXIDATIVE COUPLING; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN TRANSPORT; UCP4 GENE; WORM;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; ELECTRON TRANSPORT COMPLEX II; GENE KNOCKDOWN TECHNIQUES; ION TRANSPORT; LONGEVITY; MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; SUCCINIC ACID;

CAENORHABDITIS ELEGANS; NEMATODA;

EID: 80054822256     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.271452     Document Type: Article

References (52)

1. Cannon, B., Hedin, A., and Nedergaard, J. (1982) FEBS Lett. 150, 129-132
2. Krauss, S., Zhang, C. Y., and Lowell, B. B. (2005) Nat. Rev. Mol. Cell Biol. 6, 248-261
3. Heaton, G. M., Wagenvoord, R. J., Kemp, A., Jr., and Nicholls, D. G. (1978) Eur. J. Biochem. 82, 515-521
4. Enerback, S., Jacobsson, A., Simpson, E. M., Guerra, C., Yamashita, H., Harper, M. E., and Kozak, L. P. (1997) Nature 387, 90-94
5. Hanák, P., and Jezek, P. (2001) FEBS Lett. 495, 137-141
6. Mao, W., Yu, X. X., Zhong, A., Li, W., Brush, J., Sherwood, S. W., Adams, S. H., and Pan, G. (1999) FEBS Lett. 443, 326-330
7. Robinson, A. J., Overy, C., and Kunji, E. R. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 17766-17771
8. Gerstein, M. B., Lu, Z. J., Van Nostrand, E. L., Cheng, C., Arshinoff, B. I., Liu, T., Yip, K. Y., Robilotto, R., Rechtsteiner, A., Ikegami, K., Alves, P., Chateigner, A., Perry, M., Morris, M., Auerbach, R. K., Feng, X., Leng, J., Vielle, A., Niu, W., Rhrissorrakrai, K., Agarwal, A., Alexander, R. P., Barber, G., Brdlik, C. M., Brennan, J., Brouillet, J. J., Carr, A., Cheung, M. S., Clawson, H., Contrino, S., Dannenberg, L. O., Dernburg, A. F., Desai, A., Dick, L., Dosé, A. C., Du, J., Egelhofer, T., Ercan, S., Euskirchen, G., Ewing, B., Feingold, E. A., Gassmann, R., Good, P. J., Green, P., Gullier, F., Gutwein, M., Guyer, M. S., Habegger, L., Han, T., Henikoff, J. G., Henz, S. R., Hinrichs, A., Holster, H., Hyman, T., Iniguez, A. L., Janette, J., Jensen, M., Kato, M., Kent, W. J., Kephart, E., Khivansara, V., Khurana, E., Kim, J. K., Kolasinska-Zwierz, P., Lai, E. C., Latorre, I., Leahey, A., Lewis, S., Lloyd, P., Lochovsky, L., Lowdon, R. F., Lubling, Y., Lyne, R., MacCoss, M., Mackowiak, S. D., Mangone, M., McKay, S., Mecenas, D., Merrihew, G., Miller, D. M., 3rd, Muroyama, A., Murray, J. I., Ooi, S. L., Pham, H., Phippen, T., Preston, E. A., Rajewsky, N., Rätsch, G., Rosenbaum, H., Rozowsky, J., Rutherford, K., Ruzanov, P., Sarov, M., Sasidharan, R., Sboner, A., Scheid, P., Segal, E., Shin, H., Shou, C., Slack, F. J., Slightam, C., Smith, R., Spencer, W. C., Stinson, E. O., Taing, S., Takasaki, T., Vafeados, D., Voronina, K., Wang, G., Washington, N. L., Whittle, C. M., Wu, B., Yan, K. K., Zeller, G., Zha, Z., Zhong, M., Zhou, X., Ahringer, J., Strome, S., Gunsalus, K. C., Micklem, G., Liu, X. S., Reinke, V., Kim, S. K., Hillier, L. W., Henikoff, S., Piano, F., Snyder, M., Stein, L., Lieb, J. D., and Waterston, R. H. (2010) Science 330, 1775-1787
9. McKay, R. M., McKay, J. P., Avery, L., and Graff, J. M. (2003) Dev. Cell 4, 131-142
10. Kayser, E. B., Morgan, P. G., Hoppel, C. L., and Sedensky, M. M. (2001) J. Biol. Chem. 276, 20551-20558
11. Kayser, E. B., Sedensky, M. M., Morgan, P. G., and Hoppel, C. L. (2004) J. Biol. Chem. 279, 54479-54486
12. Lippitt, B., McCord, J. M., and Fridovich, I. (1972) J. Biol. Chem. 247, 4688-4690
13. Brand, M. D., Pakay, J. L., Ocloo, A., Kokoszka, J., Wallace, D. C., Brookes, P. S., and Cornwall, E. J. (2005) Biochem. J. 392, 353-362
14. Hoppel, C., DiMarco, J. P., and Tandler, B. (1979) J. Biol. Chem. 254, 4164-4170
15. Mak, H. Y., Nelson, L. S., Basson, M., Johnson, C. D., and Ruvkun, G. (2006) Nat. Genet. 38, 363-368
16. Brock, T. J., Browse, J., and Watts, J. L. (2006) PLoS Genet. 2, e108
17. Jonassen, T., Marbois, B. N., Faull, K. F., Clarke, C. F., and Larsen, P. L. (2002) J. Biol. Chem. 277, 45020-45027
18. Talbot, D. A., Lambert, A. J., and Brand, M. D. (2004) FEBS Lett. 556, 111-115
19. Hartman, P. S., Ishii, N., Kayser, E. B., Morgan, P. G., and Sedensky, M. M. (2001) Mech. Ageing Dev. 122, 1187-1201
20. Jaburek, M., and Garlid, K. D. (2003) J. Biol. Chem. 278, 25825-25831
21. Ivanova, M. V., Hoang, T., McSorley, F. R., Krnac, G., Smith, M. D., and Jelokhani-Niaraki, M. (2010) Biochemistry 49, 512-521
22. Jonassen, T., Larsen, P. L., and Clarke, C. F. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 421-426
23. Falk, M. J., Rosenjack, J. R., Polyak, E., Suthammarak, W., Chen, Z., Morgan, P. G., and Sedensky, M. M. (2009) PLoS One 4, e6607
24. Kaplan, R. S., and Pedersen, P. L. (1985) J. Biol. Chem. 260, 10293-10298
25. Palmieri, L., Picault, N., Arrigoni, R., Besin, E., Palmieri, F., and Hodges, M. (2008) Biochem. J. 410, 621-629
26. Parker, N., Vidal-Puig, A., and Brand, M. D. (2008) Biosci. Rep. 28, 83-88
27. Ishii, N., Takahashi, K., Tomita, S., Keino, T., Honda, S., Yoshino, K., and Suzuki, K. (1990) Mutat. Res. 237, 165-171
28. Ishii, N., Fujii, M., Hartman, P. S., Tsuda, M., Yasuda, K., Senoo-Matsuda, N., Yanase, S., Ayusawa, D., and Suzuki, K. (1998) Nature 394, 694-697
29. Lee, H. J., Ryu, H. J., Shin, H. D., Park, B. L., Kim, J. Y., Cho, Y. M., Park, K. S., Song, J., and Oh, B. (2008) Clin. Chim. Acta 398, 27-33
30. Szolnoki, Z., Kondacs, A., Mandi, Y., Bodor, A., and Somogyvari, F. (2009) Neuromolecular Med. 11, 101-105
31. Szolnoki, Z., Kondacs, A., Mandi, Y., Bodor, A., and Somogyvari, F. (2011) Acta Neurol. Scand. 123, 352-357
32. Yasuno, K., Ando, S., Misumi, S., Makino, S., Kulski, J. K., Muratake, T., Kaneko, N., Amagane, H., Someya, T., Inoko, H., Suga, H., Kanemoto, K., and Tamiya, G. (2007) Am. J. Med. Genet. B Neuropsychiatr. Genet. 144B, 250-253
33. Jezek, P., Jabůrek, M., and Garlid, K. D. (2010) FEBS Lett. 584, 2135-2141
34. Urbánková, E., Hanák, P., Skobisová, E., Růzicka, M., and Jezek, P. (2003) Int. J. Biochem. Cell Biol. 35, 212-220
35. Sokolova, I. M., and Sokolov, E. P. (2005) FEBS Lett. 579, 313-317
36. Owen, O. E., Kalhan, S. C., and Hanson, R. W. (2002) J. Biol. Chem. 277, 30409-30412
37. DeBerardinis, R. J., Lum, J. J., Hatzivassiliou, G., and Thompson, C. B. (2008) Cell Metab. 7, 11-20
38. Palmieri, F. (2004) Pflugers Arch. 447, 689-709
39. Klingenberg, M., Winkler, E., and Echtay, K. (2001) Biochem. Soc. Trans. 29, 806-811
40. Smorodchenko, A., Rupprecht, A., Sarilova, I., Ninnemann, O., Bräuer, A. U., Franke, K., Schumacher, S., Techritz, S., Nitsch, R., Schuelke, M., and Pohl, E. E. (2009) Biochim. Biophys. Acta 1788, 2309-2319
41. Iser, W. B., Kim, D., Bachman, E., and Wolkow, C. (2005) Mech. Ageing Dev. 126, 1090-1096
42. Ichimiya, H., Huet, R. G., Hartman, P., Amino, H., Kita, K., and Ishii, N. (2002) Mitochondrion 2, 191-198
43. Ishii, N., Ishii, T., and Hartman, P. S. (2006) Exp. Gerontol. 41, 952-956
44. Senoo-Matsuda, N., Yasuda, K., Tsuda, M., Ohkubo, T., Yoshimura, S., Nakazawa, H., Hartman, P. S., and Ishii, N. (2001) J. Biol. Chem. 276, 41553-41558
45. Speakman, J. R., Talbot, D. A., Selman, C., Snart, S., McLaren, J. S., Redman, P., Krol, E., Jackson, D. M., Johnson, M. S., and Brand, M. D. (2004) Aging Cell 3, 87-95
46. Toma, I., Kang, J. J., Sipos, A., Vargas, S., Bansal, E., Hanner, F., Meer, E., and Peti-Peterdi, J. (2008) J. Clin. Invest. 118, 2526-2534
47. Sapieha, P., Sirinyan, M., Hamel, D., Zaniolo, K., Joyal, J. S., Cho, J. H., Honoré, J. C., Kermorvant-Duchemin, E., Varma, D. R., Tremblay, S., Leduc, M., Rihakova, L., Hardy, P., Klein, W. H., Mu, X., Mamer, O., Lachapelle, P., Di Polo, A., Beauséjour, C., Andelfinger, G., Mitchell, G., Sennlaub, F., and Chemtob, S. (2008) Nat. Med. 14, 1067-1076
48. Hakak, Y., Lehmann-Bruinsma, K., Phillips, S., Le, T., Liaw, C., Connolly, D. T., and Behan, D. P. (2009) J. Leukoc. Biol. 85, 837-843
49. Rubic, T., Lametschwandtner, G., Jost, S., Hinteregger, S., Kund, J., Carballido- Perrig, N., Schwärzler, C., Junt, T., Voshol, H., Meingassner, J. G., Mao, X., Werner, G., Rot, A., and Carballido, J. M. (2008) Nat. Immunol. 9, 1261-1269
50. Nakamichi, N., Fukushima, A., Kusano, M., Sakakibara, H., Mizuno, T., and Saito, K. (2009) Plant Signal. Behav. 4, 660-662
51. Tanaka, Y., Okamoto, K., Teye, K., Umata, T., Yamagiwa, N., Suto, Y., Zhang, Y., and Tsuneoka, M. (2010) EMBO J. 29, 1510-1522
52. Selak, M. A., Armour, S. M., MacKenzie, E. D., Boulahbel, H., Watson, D. G., Mansfield, K. D., Pan, Y., Simon, M. C., Thompson, C. B., and Gottlieb, E. (2005) Cancer Cell 7, 77-85