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Volumn 7, Issue 11, 2011, Pages 1365-1382

Pharmacogenetics of the lipodystrophy syndrome associated with HIV infection and combination antiretroviral therapy

Author keywords

Antiretroviral therapy; HIV infection; Lipodystrophy; Pharmacogenetics

Indexed keywords

ADIPOCYTOKINE; ADIPONECTIN; ANTIRETROVIRUS AGENT; APOLIPOPROTEIN C3; ARYLDIALKYLPHOSPHATASE 1; BETA 3 ADRENERGIC RECEPTOR; CYTOKINE; DIDANOSINE; EFAVIRENZ; HLA B ANTIGEN; INTERLEUKIN 1; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERSTITIAL COLLAGENASE; LAMIN A; LAMIVUDINE PLUS ZIDOVUDINE; LEPTIN; MITOCHONDRIAL DNA; NELFINAVIR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; STAVUDINE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 4; TOLL LIKE RECEPTOR 4; ZIDOVUDINE;

EID: 80054751309     PISSN: 17425255     EISSN: 17447607     Source Type: Journal    
DOI: 10.1517/17425255.2011.621941     Document Type: Review
Times cited : (7)

References (108)
  • 1
    • 23044432814 scopus 로고    scopus 로고
    • Antiretroviral therapy for HIV: Medical miracles do happen
    • DOI 10.1016/S0140-6736(05)67002-X, PII S014067360567002X
    • Gazzard B. Antiretroviral therapy for HIV: medical miracles do happen. Lancet 2005;366:346-7 (Pubitemid 41073943)
    • (2005) Lancet , vol.366 , Issue.9483 , pp. 346-347
    • Gazzard, B.1
  • 2
    • 79951822455 scopus 로고    scopus 로고
    • Restoration of T cell responses to toxoplasma gondii after successful combined antiretroviral therapy in patients with AIDS with previous toxoplasmic encephalitis
    • Lejeune M, Miro JM, De Lazzari E, et al. Restoration of T cell responses to toxoplasma gondii after successful combined antiretroviral therapy in patients with AIDS with previous toxoplasmic encephalitis. Clin Infect Dis 2011;52:662-70
    • (2011) Clin Infect Dis , vol.52 , pp. 662-70
    • Lejeune, M.1    Miro, J.M.2    De Lazzari, E.3
  • 3
    • 0034709676 scopus 로고    scopus 로고
    • Stopping primary prophylaxis in HIV-1-infected patients at high risk of. Toxoplasma encephalitis. Swiss HIV Cohort Study
    • Furrer H, Opravil M, Bernasconi E, et al. Stopping primary prophylaxis in HIV-1-infected patients at high risk of. Toxoplasma encephalitis. Swiss HIV Cohort Study. Lancet 2000;355:2217-28
    • (2000) Lancet , vol.355 , pp. 2217-28
    • Furrer, H.1    Opravil, M.2    Bernasconi, E.3
  • 5
    • 67349228443 scopus 로고    scopus 로고
    • Lipodystrophies: Disorders of adipose tissue biology
    • Garg A, Agarwal AK. Lipodystrophies: disorders of adipose tissue biology. Biochim Biophys Acta 2009;1791:507-13
    • (2009) Biochim Biophys Acta , vol.1791 , pp. 507-13
    • Garg, A.1    Agarwal, A.K.2
  • 6
    • 0032493043 scopus 로고    scopus 로고
    • A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors
    • DOI 10.1097/00002030-199807000-00003
    • Carr A, Samaras K, Burton S, et al. A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors. AIDS 1998;12:F51-8 (Pubitemid 28190689)
    • (1998) AIDS , vol.12 , Issue.7
    • Carr, A.1    Samaras, K.2    Burton, S.3    Law, M.4    Freund, J.5    Chisholm, D.J.6    Cooper, D.A.7
  • 8
    • 12844276053 scopus 로고    scopus 로고
    • Lipodystrophy associated with highly active anti-retroviral therapy for HIV infection: The adipocyte as a target of anti-retroviral-induced mitochondrial toxicity
    • DOI 10.1016/j.tips.2004.12.005, PII S0165614704003190
    • Villarroya F, Domingo P, Giralt M. Lipodystrophy associated with highly active anti-retroviral therapy for HIV infection: the adipocyte as a target of anti-retroviral-induced mitochondrial toxicity. Trends Pharmacol Sci 2005;26:88-93 (Pubitemid 40170171)
    • (2005) Trends in Pharmacological Sciences , vol.26 , Issue.2 , pp. 88-93
    • Villarroya, F.1    Domingo, P.2    Giralt, M.3
  • 9
    • 77953365087 scopus 로고    scopus 로고
    • Epidemiology, assessment, and management of excess abdominal fat in persons with HIV infection
    • Moyle G, Moutschen M, Martinez E, et al. Epidemiology, assessment, and management of excess abdominal fat in persons with HIV infection. AIDS Rev 2010;12:3-14
    • (2010) AIDS Rev , vol.12 , pp. 3-14
    • Moyle, G.1    Moutschen, M.2    Martinez, E.3
  • 10
    • 76049109697 scopus 로고    scopus 로고
    • Drug-induced lipotoxicity: Lipodystrophy associated with HIV infection and antiretroviral treatment
    • Villarroya F, Domingo P, Giralt M. Drug-induced lipotoxicity: lipodystrophy associated with HIV infection and antiretroviral treatment. Biochim Biophys Acta 2010;1801:392-9
    • (2010) Biochim Biophys Acta , vol.1801 , pp. 392-9
    • Villarroya, F.1    Domingo, P.2    Giralt, M.3
  • 12
    • 0032554569 scopus 로고    scopus 로고
    • 'Buffalo hump' in men with HIV-1 infection
    • DOI 10.1016/S0140-6736(97)11443-X
    • Lo JC, Mulligan K, Tai VW, et al. "Buffalo hump" in men with HIV-1 infection. Lancet 1998;351:867-70 (Pubitemid 28121175)
    • (1998) Lancet , vol.351 , Issue.9106 , pp. 867-870
    • Lo, J.C.1    Mulligan, K.2    Tai, V.W.3    Algren, H.4    Schambelan, M.5
  • 13
    • 0032554552 scopus 로고    scopus 로고
    • Visceral abdominal-fat accumulation associated with the use of indinavir
    • Miller KD, Jones E, Yanovski JA, et al. Visceral abdominal-fat accumulation associated with the use of indinavir. Lancet 1998;351:71-5
    • (1998) Lancet , vol.351 , pp. 71-5
    • Miller, K.D.1    Jones, E.2    Yanovski, J.A.3
  • 15
    • 0033391005 scopus 로고    scopus 로고
    • A syndrome of peripheral fat wasting (lipodystrophy) in patients receiving long-term nucleoside analogue therapy
    • Saint-Marc T, Partisani M, Poizot-Martin I, et al. A syndrome of peripheral fat wasting (lipodystrophy) in patients receiving long-term nucleoside analogue therapy. AIDS 1999;13:1657-67
    • (1999) AIDS , vol.13 , pp. 1657-67
    • Saint-Marc, T.1    Partisani, M.2    Poizot-Martin, I.3
  • 16
    • 0033924871 scopus 로고    scopus 로고
    • Contribution of nucleoside analogue reverse transcriptase inhibitors to subcutaneous fat wasting in patients with HIV infection
    • DOI 10.1097/00002030-200007070-00002
    • Mallal SA, John M, Moore CB, et al. Contribution of nucleoside analogue reverse transcriptase inhibitors to subcutaneous fat wasting in patients with HIV infection. AIDS 2000;14:1309-16 (Pubitemid 30459502)
    • (2000) AIDS , vol.14 , Issue.10 , pp. 1309-1316
    • Mallal, S.A.1    John, M.2    Moore, C.B.3    James, I.R.4    McKinnon, E.J.5
  • 17
    • 0037032941 scopus 로고    scopus 로고
    • Increased risk of lipoatrophy under stavudine in HIV-1-infected patients: Results of a substudy from a comparative trial
    • DOI 10.1097/00002030-200212060-00010
    • Joly V, Flandre P, Meiffredy V, et al. Increased risk of lipoatrophy under stavudine in HIV-1-infected patients: results of a substudy from a comparative trial. AIDS 2002;16:2447-54 (Pubitemid 35471693)
    • (2002) AIDS , vol.16 , Issue.18 , pp. 2447-2454
    • Joly, V.1    Flandre, P.2    Meiffredy, V.3    Leturque, N.4    Harel, M.5    Aboulker, J.-P.6    Yeni, P.7
  • 18
    • 0038708272 scopus 로고    scopus 로고
    • Prospective evaluation of the effects of antiretroviral therapy on body composition in HIV-1-infected men starting therapy
    • DOI 10.1097/00002030-200305020-00005
    • Mallon PW, Miller J, Cooper DA, Carr A. Prospective evaluation on the effects of antiretroviral therapy on body composition in HIV-1 infected men starting therapy. AIDS 2003;17:971-9 (Pubitemid 36549708)
    • (2003) AIDS , vol.17 , Issue.7 , pp. 971-979
    • Mallon, P.W.G.1    Miller, J.2    Cooper, D.A.3    Carr, A.4
  • 20
    • 77952420363 scopus 로고    scopus 로고
    • HIV-associated lipodystrophy: From fat injury to premature aging
    • Caron-Debarle M, Lagathu C, Boccara F, et al. HIV-associated lipodystrophy: from fat injury to premature aging. Trends Mol Med 2010;16:218-29
    • (2010) Trends Mol Med , vol.16 , pp. 218-29
    • Caron-Debarle, M.1    Lagathu, C.2    Boccara, F.3
  • 21
    • 33846681647 scopus 로고    scopus 로고
    • Pharmacogenetics of antiretroviral drugs for the treatment of HIV-infected patients: An update
    • DOI 10.1016/j.meegid.2006.08.004, PII S1567134806000980
    • Cressey TR, Lallemant M. Pharmacogenetics of antiretroviral drugs for the treatment of HIV-infected patients: An update. Infect Genet Evol 2007;7:333-42 (Pubitemid 46187499)
    • (2007) Infection, Genetics and Evolution , vol.7 , Issue.2 , pp. 333-342
    • Cressey, T.R.1    Lallemant, M.2
  • 22
    • 36148965532 scopus 로고    scopus 로고
    • Toxicogenetics of antiretroviral therapy: Genetic factors that contribute to metabolic complications
    • Tarr PE, Telenti A. Toxicogenetics of antiretroviral therapy: genetic factors that contribute to metabolic complications. Antivir Ther 2007;12:999-1013 (Pubitemid 350114980)
    • (2007) Antiviral Therapy , vol.12 , Issue.7 , pp. 999-1013
    • Tarr, P.E.1    Telenti, A.2
  • 23
    • 79959524146 scopus 로고    scopus 로고
    • A haplotype map of the human genome
    • The International HapMap Consortium
    • The International HapMap Consortium. A haplotype map of the human genome. Nature 2005;437:1299-320
    • (2005) Nature , vol.437 , pp. 1299-320
  • 24
    • 26244444318 scopus 로고    scopus 로고
    • What makes a good genetic association study?
    • DOI 10.1016/S0140-6736(05)67531-9, PII S0140673605675319
    • Hattersley AT, McCarthy MI. What makes a good genetic association study? Lancet 2005;366:1315-23 (Pubitemid 41416588)
    • (2005) Lancet , vol.366 , Issue.9493 , pp. 1315-1323
    • Hattersley, A.T.1    McCarthy, M.I.2
  • 26
    • 0037426052 scopus 로고    scopus 로고
    • Problems of reporting genetic associations with complex outcomes
    • DOI 10.1016/S0140-6736(03)12715-8
    • Colhoun HM, McKeigue PM, Davey SG. Problems of reporting genetic associations with complex outcomes. Lancet 2003;361:865-72 (Pubitemid 36331853)
    • (2003) Lancet , vol.361 , Issue.9360 , pp. 865-872
    • Colhoun, H.M.1    McKeigue, P.M.2    Smith, G.D.3
  • 27
    • 24144492361 scopus 로고    scopus 로고
    • Guidelines for association studies in Human Molecular Genetics
    • DOI 10.1093/hmg/ddi251
    • Freimer NB, Sabatti C. Guidelines for association studies in Human Molecular Genetics. Hum Mol Genet 2005;14:2481-3 (Pubitemid 41236060)
    • (2005) Human Molecular Genetics , vol.14 , Issue.17 , pp. 2481-2483
    • Freimer, N.B.1    Sabatti, C.2
  • 29
    • 0035964717 scopus 로고    scopus 로고
    • Mitochondrial DNA decrease in subcutaneous adipose tissue of HIV-infected individuals with peripheral lipoatrophy
    • DOI 10.1097/00002030-200109280-00009
    • Shikuma CM, Hu N, Milne C, et al. Mitochondrial DNA decrease in subcutaneous adipose tissue of HIV-infected individuals with peripheral lipoatrophy. AIDS 2001;15:1801-9 (Pubitemid 32939241)
    • (2001) AIDS , vol.15 , Issue.14 , pp. 1801-1809
    • Shikuma, C.M.1    Hu, N.2    Milne, C.3    Yost, F.4    Waslien, C.5    Shimizu, S.6    Shiramizu, B.7
  • 30
    • 0037999080 scopus 로고    scopus 로고
    • Mitochondrial DNA depletion and morphologic changes in adipocytes associated with nucleoside reverse transcriptase inhibitor therapy
    • DOI 10.1097/00002030-200306130-00007
    • Nolan D, Hammond E, Martin A, et al. Mitochondrial DNA depletion and morphologic changes in adipocytes associated with nucleoside reverse transcriptase inhibitor therapy. AIDS 2003;17:1329-38 (Pubitemid 36819847)
    • (2003) AIDS , vol.17 , Issue.9 , pp. 1329-1338
    • Nolan, D.1    Hammond, E.2    Martin, A.3    Taylor, L.4    Herrmann, S.5    McKinnon, E.6    Metcalf, C.7    Latham, B.8    Mallal, S.9
  • 31
    • 49949117158 scopus 로고    scopus 로고
    • Mitochondrial RNA and DNA alterations in HIV lipoatrophy are linked to antiretroviral therapy and not to HIV infection
    • McComsey GA, Libutti DE, O'Riordan M, et al. Mitochondrial RNA and DNA alterations in HIV lipoatrophy are linked to antiretroviral therapy and not to HIV infection. Antivir Ther 2008;13:715-22
    • (2008) Antivir Ther , vol.13 , pp. 715-22
    • McComsey, G.A.1    Libutti, D.E.2    O'Riordan, M.3
  • 33
    • 10044232783 scopus 로고    scopus 로고
    • Could mitochondrial DNA quantitation be a surrogate marker for drug mitochondrial toxicity?
    • de Mendoza C, Sanchez-Conde M, Ribera E, et al. Could be mitochondrial DNA quantitation a surrogate marker for drug mitochondrial toxicity. AIDS Rev 2004;6:169-80 (Pubitemid 39599987)
    • (2004) AIDS Reviews , vol.6 , Issue.3 , pp. 169-180
    • De Mendoza, C.1    Sanchez-Conde, M.2    Ribera, E.3    Domingo, P.4    Soriano, V.5
  • 35
    • 0037040365 scopus 로고    scopus 로고
    • Analysis of the mitochondrial DNA genome in the peripheral blood leukocytes of HIV-infected patients with or without lipoatrophy
    • DOI 10.1097/00002030-200203080-00001
    • McComsey G, Tan DJ, Lederman M, et al. Analysis of mitochondrial DNA genome in the peripheral blood leukocytes of HIV-infected patients with or without lipoatrophy. AIDS 2002;16:513-18 (Pubitemid 34218845)
    • (2002) AIDS , vol.16 , Issue.4 , pp. 513-518
    • McComsey, G.1    Tan, D.-J.2    Lederman, M.3    Wilson, E.4    Wong, L.-J.5
  • 37
    • 79751520133 scopus 로고    scopus 로고
    • No longitudinal mitochondrial DNA sequence changes in HIV-infected individuals with and without lipoatrophy
    • Ortiz M, Poloni ES, Furrer H, et al. No longitudinal mitochondrial DNA sequence changes in HIV-infected individuals with and without lipoatrophy. J Infect Dis 2011;201:620-4
    • (2011) J Infect Dis , vol.201 , pp. 620-4
    • Ortiz, M.1    Poloni, E.S.2    Furrer, H.3
  • 38
    • 52449098059 scopus 로고    scopus 로고
    • Mitochondrial DNA haplogroups and highly active antiretroviral therapy-related lipodystrophy
    • Nasi M, Guaraldi G, Orlando G, et al. Mitochondrial DNA haplogroups and highly active antiretroviral therapy-related lipodystrophy. Clin Infect Dis 2008;47:962-8
    • (2008) Clin Infect Dis , vol.47 , pp. 962-8
    • Nasi, M.1    Guaraldi, G.2    Orlando, G.3
  • 40
    • 67649185305 scopus 로고    scopus 로고
    • Mitochondrial DNA haplogroups influence lipoatrophy after highly active antiretroviral therapy
    • Hendrikson SL, Kingsley LA, Ruiz-Pesini E, et al. Mitochondrial DNA haplogroups influence lipoatrophy after highly active antiretroviral therapy. J Acquir Immune Defic Syndr 2009;51:111-16
    • (2009) J Acquir Immune Defic Syndr , vol.51 , pp. 111-16
    • Hendrikson, S.L.1    Kingsley, L.A.2    Ruiz-Pesini, E.3
  • 41
    • 78650307290 scopus 로고    scopus 로고
    • European mitochondrial DNA haplogroups and metabolic changes dring antiretroviral therapy in AIDS Clinical Trials Group Study A5142
    • Hulgan T, Haubrich R, Riddler S, et al. European mitochondrial DNA haplogroups and metabolic changes dring antiretroviral therapy in AIDS Clinical Trials Group Study A5142. AIDS 2011;25:37-47
    • (2011) AIDS , vol.25 , pp. 37-47
    • Hulgan, T.1    Haubrich, R.2    Riddler, S.3
  • 42
    • 64749084609 scopus 로고    scopus 로고
    • Relationship between polymerase gamma (POLG) polymorphisms and antiretroviral therapy-induced lipodystrophy in HIV-1 infected patients: A case-control study
    • Chiappini F, Teicher E, Saffroy R, et al. Relationship between polymerase gamma (POLG) polymorphisms and antiretroviral therapy-induced lipodystrophy in HIV-1 infected patients: a case-control study. Curr HIV Res 2009;7:244-53
    • (2009) Curr HIV Res , vol.7 , pp. 244-53
    • Chiappini, F.1    Teicher, E.2    Saffroy, R.3
  • 43
    • 37349006913 scopus 로고    scopus 로고
    • TNF-alpha and adipocyte biology
    • Cawthorn WP, Sethi JK. TNF-alpha and adipocyte biology. FEBS Lett 2008;582:117-31
    • (2008) FEBS Lett , vol.582 , pp. 117-31
    • Cawthorn, W.P.1    Sethi, J.K.2
  • 45
    • 0034657296 scopus 로고    scopus 로고
    • Alteration of tumor necrosis factor-α T-cell homeostasis following potent antiretroviral therapy: Contribution to the development of human immunodeficiency virus-associated lipodystrophy syndrome
    • Ledru E, Christeff N, Patey O, et al. Alteration of tumor necrosis factor-alpha T-cell homeostasis following potent antiretroviral therapy: contribution to the development of human immunodeficiency virus-associated lipodystrophy syndrome. Blood 2000;95:3191-8 (Pubitemid 30321172)
    • (2000) Blood , vol.95 , Issue.10 , pp. 3191-3198
    • Ledru, E.1    Christeff, N.2    Patey, O.3    De Truchis, P.4    Melchior, J.-C.5    Gougeon, M.-L.6
  • 48
    • 33748117796 scopus 로고    scopus 로고
    • Interleukin-6: Discovery of a pleiotropic cytokine
    • Kishimoto T. Interleukin-6: discovery of a pleiotropic cytokine. Arthritis Res Ther 2006;8(Suppl 2):S2
    • (2006) Arthritis Res Ther , vol.8 , Issue.SUPPL. 2
    • Kishimoto, T.1
  • 52
    • 0042732970 scopus 로고    scopus 로고
    • Expression of adipogenic transcription factors, peroxisome proliferator-activated receptor gamma co-activator 1, IL-6 and CD45 in subcutaneous adipose tissue in lipodystrophy associated with highly active antiretroviral therapy
    • DOI 10.1097/00002030-200308150-00004
    • Kannisto K, Sutinen J, Korsheninnikova E, et al. Expression of adipogenic transcription factors, peroxisome proliferator-activated receptor gamma co-activator 1, IL-6 and CD45 in subcutaneous adipose tissue in lipodystrophy associated with highly active antiretroviral therapy. AIDS 2003;17:1753-62 (Pubitemid 37000093)
    • (2003) AIDS , vol.17 , Issue.12 , pp. 1753-1762
    • Kannisto, K.1    Sutinen, J.2    Korsheninnikova, E.3    Fisher, R.M.4    Ehrenborg, E.5    Gertow, K.6    Virkamaki, A.7    Nyman, T.8    Vidal, H.9    Hamsten, A.10    Yki-Jarvinen, H.11
  • 55
    • 77949751469 scopus 로고    scopus 로고
    • Potential role of IL-18 in the immunopathogenesis of AIDS, HIV-associated lipodystrophy and related clinical conditions
    • Iannello A, Samarani S, Debbeche O, et al. Potential role of IL-18 in the immunopathogenesis of AIDS, HIV-associated lipodystrophy and related clinical conditions. Curr HIV Res 2010;8:147-64
    • (2010) Curr HIV Res , vol.8 , pp. 147-64
    • Iannello, A.1    Samarani, S.2    Debbeche, O.3
  • 56
    • 0037131198 scopus 로고    scopus 로고
    • TNF-α promoter region gene polymorphisms in HIV-positive patients with lipodystrophy
    • DOI 10.1097/00002030-200210180-00005
    • Maher B, Alfirevic A, Vilar FJ, et al. TNF-alpha promoter region gene polymorphisms in HIV-positive patients with lipodystrophy. AIDS 2002;16:2013-18 (Pubitemid 35205264)
    • (2002) AIDS , vol.16 , Issue.15 , pp. 2013-2018
    • Maher, B.1    Alfirevic, A.2    Javier Vilar, F.3    Wilkins, E.G.L.4    Park, B.K.5    Pirmohamed, M.6
  • 58
    • 40949114659 scopus 로고    scopus 로고
    • IL-1beta (+3954C/T) polymorphism could protect HIV-infected patients on HAART against the lipodystrophic syndrome
    • Asensi V, Rego C, Montes AH, et al. IL-1beta (+3954C/T) polymorphism could protect HIV-infected patients on HAART against the lipodystrophic syndrome. Genet Med 2008;10:215-23
    • (2008) Genet Med , vol.10 , pp. 215-23
    • Asensi, V.1    Rego, C.2    Montes, A.H.3
  • 59
    • 0037415033 scopus 로고    scopus 로고
    • Tumour necrosis factor-alpha gene -238G/A promoter polymorphism associated with a more rapid onset of lipodystrophy
    • DOI 10.1097/00002030-200301030-00017
    • Nolan D, Moore C, Castley A, et al. Tumour necrosis factor-alpha gene-238G/A promoter polymorphism associated with a more rapid onset of lipodystrophy. AIDS 2003;17:121-3 (Pubitemid 36106307)
    • (2003) AIDS , vol.17 , Issue.1 , pp. 121-123
    • Nolan, D.1    Moore, C.2    Castley, A.3    Sayer, D.4    Mamotte, C.5    John, M.6    James, I.7    Mallal, S.8
  • 60
    • 79951717673 scopus 로고    scopus 로고
    • No relationship between TNF-alpha genetic variants and combination antiretroviral therapy-related lipodystrophy syndrome in HIV type 1-infected patients: A case-control study and a meta-analysis
    • Veloso S, Olona M, Peraire J, et al. No relationship between TNF-alpha genetic variants and combination antiretroviral therapy-related lipodystrophy syndrome in HIV type 1-infected patients: a case-control study and a meta-analysis. AIDS Res Hum Retroviruses 2011;27:143-52
    • (2011) AIDS Res Hum Retroviruses , vol.27 , pp. 143-52
    • Veloso, S.1    Olona, M.2    Peraire, J.3
  • 62
    • 77954347656 scopus 로고    scopus 로고
    • Interleukin-18 and interferon-gamma polymorphisms in Brazilian human immunodeficiency virus-1-infected patients presenting with lipodystrophy syndrome
    • Castelar L, Silva MM, Castell EC, et al. Interleukin-18 and interferon-gamma polymorphisms in Brazilian human immunodeficiency virus-1-infected patients presenting with lipodystrophy syndrome. Tissue Antigens 2010;76:126-30
    • (2010) Tissue Antigens , vol.76 , pp. 126-30
    • Castelar, L.1    Silva, M.M.2    Castell, E.C.3
  • 63
    • 70349314629 scopus 로고    scopus 로고
    • Adipokines as novel modulators of lipid metabolism
    • Lago F, Gomez R, Gomez-Reino JJ, et al. Adipokines as novel modulators of lipid metabolism. Trends Biochem Sci 2009;34:500-11
    • (2009) Trends Biochem Sci , vol.34 , pp. 500-11
    • Lago, F.1    Gomez, R.2    Gomez-Reino, J.J.3
  • 64
    • 74949143243 scopus 로고    scopus 로고
    • Narrative review: The role of leptin in human physiology: Clinical applications
    • Kelesidis T, Kelesidis I, Chou S, Mantzoros CS. Narrative review: the role of leptin in human physiology: clinical applications. Ann Intern Med 2010;152:93-100
    • (2010) Ann Intern Med , vol.152 , pp. 93-100
    • Kelesidis, T.1    Kelesidis, I.2    Chou, S.3    Mantzoros, C.S.4
  • 65
    • 34548162342 scopus 로고    scopus 로고
    • Pathophysiological significance of adiponectin
    • DOI 10.1007/s00795-007-0366-7
    • Nishida M, Funahashi T, Shimomura I. Pathophysiological significance of adiponectin. Med Mol Morphol 2007;40:55-67 (Pubitemid 47305235)
    • (2007) Medical Molecular Morphology , vol.40 , Issue.2 , pp. 55-67
    • Nishida, M.1    Funahashi, T.2    Shimomura, I.3
  • 66
    • 1842506529 scopus 로고    scopus 로고
    • The current biology of resistin
    • DOI 10.1111/j.1365-2796.2004.01306.x
    • Steppan CM, Lazar MA. The current biology of resistin. J Intern Med 2005;255:439-47 (Pubitemid 38446357)
    • (2004) Journal of Internal Medicine , vol.255 , Issue.4 , pp. 439-447
    • Steppan, C.M.1    Lazar, M.A.2
  • 67
    • 34247592922 scopus 로고    scopus 로고
    • The role of adipokines in relation to HIV lipodystrophy
    • DOI 10.1097/QAD.0b013e3280adc91e, PII 0000203020070511000001
    • Sweeney LL, Brennan AM, Mantzoros CS. The role of adipokines in relation to HIV lipodystrophy. AIDS 2007;21:895-904 (Pubitemid 46684320)
    • (2007) AIDS , vol.21 , Issue.8 , pp. 895-904
    • Sweeney, L.L.1    Brennan, A.M.2    Mantzoros, C.S.3
  • 69
    • 52249097842 scopus 로고    scopus 로고
    • Genetic analysis implicates resistin in HIV lipodystrophy
    • Ranade K, Geese WJ, Noor M, et al. Genetic analysis implicates resistin in HIV lipodystrophy. AIDS 2008;22:1561-8
    • (2008) AIDS , vol.22 , pp. 1561-8
    • Ranade, K.1    Geese, W.J.2    Noor, M.3
  • 70
    • 79954997498 scopus 로고    scopus 로고
    • Lypodystrophy and insulin resistance in HIV-1-infected patients treated with antiretroviral drugs: Implication of resistin
    • Escote X, Miranda M, Veloso S, et al. Lypodystrophy and insulin resistance in HIV-1-infected patients treated with antiretroviral drugs: implication of resistin. J Acquir Immune Defic Syndr 2011;57:16-23
    • (2011) J Acquir Immune Defic Syndr , vol.57 , pp. 16-23
    • Escote, X.1    Miranda, M.2    Veloso, S.3
  • 71
    • 78049289406 scopus 로고    scopus 로고
    • SNPs in the APM1 gene promoter are associated with adiponectin levels in HIV-infected individuals receiving HAART
    • Trinca JR, Sprinz E, Lazzaretti RK, et al. SNPs in the APM1 gene promoter are associated with adiponectin levels in HIV-infected individuals receiving HAART. J Acquir Immune Defic Syndr 2010;55:299-305
    • (2010) J Acquir Immune Defic Syndr , vol.55 , pp. 299-305
    • Trinca, J.R.1    Sprinz, E.2    Lazzaretti, R.K.3
  • 72
    • 1542510700 scopus 로고    scopus 로고
    • Acquired and Inherited Lipodystrophies
    • DOI 10.1056/NEJMra025261
    • Garg A. Acquired and inherited lipodystrophies. N Engl J Med 2004;350:1220-34 (Pubitemid 38339366)
    • (2004) New England Journal of Medicine , vol.350 , Issue.12 , pp. 1220-1234
    • Garg, A.1
  • 73
    • 0015979147 scopus 로고
    • Familial lipoatrophic diabetes with dominant transmission: A new syndrome
    • Dunnigan MG, Cochrane MA, Kelly A, Scott JW. Familial lipoatrophic diabetes with dominant transmission: a new syndrome. Q J Med 1974;43:33-48
    • (1974) Q J Med , vol.43 , pp. 33-48
    • Dunnigan, M.G.1    Cochrane, M.A.2    Kelly, A.3    Scott, J.W.4
  • 74
    • 0032959251 scopus 로고    scopus 로고
    • Adipose tissue distribution pattern in patients with familial partial lipodystrophy (Dunnigan variety)
    • DOI 10.1210/jc.84.1.170
    • Garg A, Peshock RM, Fleckenstein JL. Adipose tissue distribution pattern in patients with familial partial lipodystrophy (Dunnigan variety). J Clin Endocrinol Metab 1999;84:170-4 (Pubitemid 29036696)
    • (1999) Journal of Clinical Endocrinology and Metabolism , vol.84 , Issue.1 , pp. 170-174
    • Garg, A.1    Peshock, R.M.2    Fleckenstein, J.L.3
  • 75
    • 0028015713 scopus 로고
    • Peroxisome proliferator-activated receptor (PPAR) γ: Adipose-predominant expression and induction early in adipocyte differentiation
    • DOI 10.1210/en.135.2.798
    • Chawla A, Schwarz EJ, Dimaculangan DD, Lazar MA. Peroxisome proliferator-activated receptor (PPAR) gamma: adipose-predominant expression and induction early in adipocyte differentiation. Endocrinology 1994;135:798-800 (Pubitemid 24241266)
    • (1994) Endocrinology , vol.135 , Issue.2 , pp. 798-800
    • Chawla, A.1    Schwarz, E.J.2    Dimaculangan, D.D.3    Lazar, M.A.4
  • 77
    • 58549098066 scopus 로고    scopus 로고
    • Site-dependent differences in both prelamin A and adipogenic genes in subcutaneous adipose tissue of patients with type 2 familial partial lipodystrophy
    • Araujo-Vilar D, Lattanzi G, Gonzalez-Mendez B, et al. Site-dependent differences in both prelamin A and adipogenic genes in subcutaneous adipose tissue of patients with type 2 familial partial lipodystrophy. J Med Genet 2009;46:40-8
    • (2009) J Med Genet , vol.46 , pp. 40-8
    • Araujo-Vilar, D.1    Lattanzi, G.2    Gonzalez-Mendez, B.3
  • 79
    • 0033624514 scopus 로고    scopus 로고
    • 3-adrenergic receptor polymorphism and the antiretroviral therapy-related lipodystrophy syndrome
    • DOI 10.1097/00002030-200007070-00027
    • Vonkelman HE, Napel CHH, Oeveren-Dybicz AM, Vermes I. Beta3-adrenergic receptor polymorphism and the antiretroviral therapy-related lipodystrophy. AIDS 2000;14:1463-4 (Pubitemid 30459527)
    • (2000) AIDS , vol.14 , Issue.10 , pp. 1463-1464
    • Vonkeman, H.E.1    Ten Napel, C.H.H.2    Van Oeveren-Dybicz, A.M.3    Vermes, I.4
  • 81
    • 0036537888 scopus 로고    scopus 로고
    • A novel interaction between lamin A and SREBP1: Implications for partial lipodystrophy and other laminopathies
    • Lloyd DJ, Trembath RC, Shackleton S. A novel interaction between lamin A and SREBP1: implications for partial lipodystrophy and other laminopathies. Hum Mol Genet 2002;11:769-77 (Pubitemid 34428644)
    • (2002) Human Molecular Genetics , vol.11 , Issue.7 , pp. 769-777
    • Lloyd, D.J.1    Trembath, R.C.2    Shackleton, S.3
  • 83
    • 1042263432 scopus 로고    scopus 로고
    • Some HIV protease inhibitors alter lamin A/C maturation and stability, SREBP-1 nuclear localization and adipocyte differentiation
    • DOI 10.1097/00002030-200311210-00005
    • Caron M, Auclair M, Sterlingot H, et al. Some HIV protease inhibitors alter lamin A/C maduration and stability, SREBP-1 nuclear localization and adipocyte differentiation. AIDS 2003;17:2437-44 (Pubitemid 38393315)
    • (2003) AIDS , vol.17 , Issue.17 , pp. 2437-2444
    • Caron, M.1    Auclair, M.2    Sterlingot, H.3    Kornprobst, M.4    Capeau, J.5
  • 84
    • 0033823256 scopus 로고    scopus 로고
    • Lessons from lipdystrophy: LMNA, encoding lamin A/C in HIV therapy-associated lipodystrophy
    • Behrens GM, Lloyd D, Schmidt HH, et al. Lessons from lipdystrophy: LMNA, encoding lamin A/C in HIV therapy-associated lipodystrophy. AIDS 2000;14:1854-5
    • (2000) AIDS , vol.14 , pp. 1854-5
    • Behrens, G.M.1    Lloyd, D.2    Schmidt, H.H.3
  • 86
    • 1542602124 scopus 로고    scopus 로고
    • Lack of mutations in LMNA, its promoter region, and in the cellular retinoic acid binding protein II (CRABP II) in HIV associated lipodystrophy
    • Behrens GM, Genschel J, Schmidt RE, Schmidt HH. Lack of mutations in LMNA, its promoter region, and in the cellular retinoic acid binding protein II (CRABP II) in HIV associated lipodystrophy. Eur J Med Res 2003;30:221-5
    • (2003) Eur J Med Res , vol.30 , pp. 221-5
    • Behrens, G.M.1    Genschel, J.2    Schmidt, R.E.3    Schmidt, H.H.4
  • 89
    • 70350741541 scopus 로고    scopus 로고
    • PPARgamma Pro12Ala polymorphism in HIV-1-infected patients with HAART-related lipodystrophy
    • Saumoy M, Veloso S, Alonso-Villaverde C, et al. PPARgamma Pro12Ala polymorphism in HIV-1-infected patients with HAART-related lipodystrophy. Curr HIV Res 2009;7:533-40
    • (2009) Curr HIV Res , vol.7 , pp. 533-40
    • Saumoy, M.1    Veloso, S.2    Alonso-Villaverde, C.3
  • 90
    • 64949166842 scopus 로고    scopus 로고
    • Genetic polymorphisms differently influencing the emergence of atrophy and fat accumulation in HIV-related lipodystrophy
    • Zanone Poma B, Riva A, Nasi M, et al. Genetic polymorphisms differently influencing the emergence of atrophy and fat accumulation in HIV-related lipodystrophy. AIDS 2008;22:1769-78
    • (2008) AIDS , vol.22 , pp. 1769-78
    • Zanone Poma, B.1    Riva, A.2    Nasi, M.3
  • 91
    • 78549283756 scopus 로고    scopus 로고
    • The MMP1 (-16071G/2G) single nucleotide polymorphism associates with the HAART-related lipodystrophic syndrome
    • Montes AH, Valle-Garay E, Suarez-Zarracina T, et al. The MMP1 (-16071G/2G) single nucleotide polymorphism associates with the HAART-related lipodystrophic syndrome. AIDS 2010;24:2499-506
    • (2010) AIDS , vol.24 , pp. 2499-506
    • Montes, A.H.1    Valle-Garay, E.2    Suarez-Zarracina, T.3
  • 92
    • 78751640761 scopus 로고    scopus 로고
    • Adipogenic gene variants in patients with HIV-associated lipodystrophy
    • Pushpakom SP, Owen A, Vilar FJ, et al. Adipogenic gene variants in patients with HIV-associated lipodystrophy. Pharmacogenet Genomics 2011;21:76-83
    • (2011) Pharmacogenet Genomics , vol.21 , pp. 76-83
    • Pushpakom, S.P.1    Owen, A.2    Vilar, F.J.3
  • 94
    • 0346333250 scopus 로고    scopus 로고
    • Contribution of nucleoside-analogue reverse transcriptase inhibitor therapy to lipoatrophy from the population to the cellular level
    • Nolan D, Hammond E, James I, et al. Contribution of nucleoside-analogue reverse transcriptase inhibitor therapy to lipoatrophy from the population to the cellular level. Antivir Ther 2003;8:617-26 (Pubitemid 38057108)
    • (2003) Antiviral Therapy , vol.8 , Issue.6 , pp. 617-626
    • Nolan, D.1    Hammond, E.2    James, I.3    McKinnon, E.4    Malla, S.5
  • 95
    • 79953180935 scopus 로고    scopus 로고
    • Association of thymidylate synthase gene polymorphisms with Stavudine triphosphate intracellular levels and lipodystrophy
    • Domingo P, Cabeza MC, Pruvost A, et al. Association of thymidylate synthase gene polymorphisms with Stavudine triphosphate intracellular levels and lipodystrophy. Antimicrob Agents Chemother 2011;55:1428-35
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 1428-35
    • Domingo, P.1    Cabeza, M.C.2    Pruvost, A.3
  • 96
    • 75749110161 scopus 로고    scopus 로고
    • Association between HLA-B*4001 and lipodystrophy among HIV-infected patients from Thailand who received a stavudine-containing antiretroviral regimen
    • Wangsomboonsiri W, Mahasirimongkol S, Chantarangsu S, et al. Association between HLA-B*4001 and lipodystrophy among HIV-infected patients from Thailand who received a stavudine-containing antiretroviral regimen. Clin Infect Dis 2010;50:597-604
    • (2010) Clin Infect Dis , vol.50 , pp. 597-604
    • Wangsomboonsiri, W.1    Mahasirimongkol, S.2    Chantarangsu, S.3
  • 97
    • 75749149310 scopus 로고    scopus 로고
    • Association of Paraoxonase-1 gene haplotypes with the immunologic outcome and the metabolic disturbances and atherosclerosis in HIV-infected patients
    • Parra S, Marsillach J, Aragones G, et al. Association of Paraoxonase-1 gene haplotypes with the immunologic outcome and the metabolic disturbances and atherosclerosis in HIV-infected patients. J Infect Dis 2010;201:627-34
    • (2010) J Infect Dis , vol.201 , pp. 627-34
    • Parra, S.1    Marsillach, J.2    Aragones, G.3
  • 99
    • 0036240673 scopus 로고    scopus 로고
    • Role of nitric oxide in HIV-1 infection: Friend or foe?
    • DOI 10.1016/S1473-3099(02)00262-1
    • Torre D, Pugliese A, Speranza F. Role of nitric oxide in HIV-1 infection: friend or foe? Lancet Infect Dis 2002;2:273-80 (Pubitemid 34464738)
    • (2002) Lancet Infectious Diseases , vol.2 , Issue.5 , pp. 273-280
    • Torre, D.1    Pugliese, A.2    Speranza, F.3
  • 102
    • 77955742528 scopus 로고    scopus 로고
    • Recent insights into the role of Toll-like receptors in viral infection
    • Carty M, Bowie AG. Recent insights into the role of Toll-like receptors in viral infection. Clin Exp Immunol 2010;161:397-406
    • (2010) Clin Exp Immunol , vol.161 , pp. 397-406
    • Carty, M.1    Bowie, A.G.2
  • 103
    • 2942530690 scopus 로고    scopus 로고
    • Influence of coinfecting pathogens on HIV expression: Evidence for a role of Toll-like receptors
    • Bafica A, Scanga CA, Schito M, et al. Influence of coinfecting pathogens on HIV expression: evidence for a role of Toll-like receptors. J Immunol 2004;172:7229-34 (Pubitemid 38747580)
    • (2004) Journal of Immunology , vol.172 , Issue.12 , pp. 7229-7234
    • Bafica, A.1    Scanga, C.A.2    Schito, M.3    Chaussabel, D.4    Sher, A.5
  • 104
    • 33847021903 scopus 로고    scopus 로고
    • Polymorphism in Toll-like receptor 9 influences the clinical course of HIV.1 infection
    • Bochud PY, Hersberger M, Taffe P, et al. Polymorphism in Toll-like receptor 9 influences the clinical course of HIV.1 infection. AIDS 2007;10:441-6
    • (2007) AIDS , vol.10 , pp. 441-6
    • Bochud, P.Y.1    Hersberger, M.2    Taffe, P.3
  • 105
    • 0033794461 scopus 로고    scopus 로고
    • A novel polymorphism in the Toll-like receptor 2 gene and its potential association with staphylococcal infection
    • Lorenz F, Mira JP, Kornish KL, et al. A novel polymorphism in the Toll-like receptor 2 gene and its potential association with staphylococcal infection. Infect Immun 2002;68:6398-401
    • (2002) Infect Immun , vol.68 , pp. 6398-401
    • Lorenz, F.1    Mira, J.P.2    Kornish, K.L.3
  • 106
    • 0037071251 scopus 로고    scopus 로고
    • Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock
    • Lorenz F, Mira JP, Frees KL, Schwartz DA. Relevance of mutations in the TLR receptor in patients with Gram-negative septic shock. Arch Intern Med 2002;162:1028-32 (Pubitemid 34492532)
    • (2002) Archives of Internal Medicine , vol.162 , Issue.9 , pp. 1028-1032
    • Lorenz, E.1    Mira, J.P.2    Frees, K.L.3    Schwartz, D.A.4
  • 107
    • 33645086385 scopus 로고    scopus 로고
    • The Toll-like receptor 4 (Asp299Gly) polymorphism is a risk factor for Gram-negative and hematogenous osteomyelitis
    • Montes AH, Asensi V, Alvarez V, et al. The Toll-like receptor 4 (Asp299Gly) polymorphism is a risk factor for Gram-negative and hematogenous osteomyelitis. Clin Exp Immunol 2006;143:404-13
    • (2006) Clin Exp Immunol , vol.143 , pp. 404-13
    • Montes, A.H.1    Asensi, V.2    Alvarez, V.3
  • 108
    • 78650472774 scopus 로고    scopus 로고
    • Toll-like receptors: Linking inflammation to metabolism
    • Konner AC, Bruning JC. Toll-like receptors: linking inflammation to metabolism. Trends Endocrinol Metab 2011;22:16-23
    • (2011) Trends Endocrinol Metab , vol.22 , pp. 16-23
    • Konner, A.C.1    Bruning, J.C.2


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