Lipodystrophy associated with highly active anti-retroviral therapy for HIV infection: The adipocyte as a target of anti-retroviral-induced mitochondrial toxicity

Trends in Pharmacological Sciences

Volumn 26, Issue 2, 2005, Pages 88-93

  Villarroya, Francesc ^a   Domingo, Pere ^b   Giralt, Marta ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED DNA POLYMERASE GAMMA; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INTERLEUKIN 6; MITOCHONDRIAL DNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RNA DIRECTED DNA POLYMERASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; UNCOUPLING PROTEIN 1; UNCOUPLING PROTEIN 2; UNCOUPLING PROTEIN 3;

ADIPOCYTE; ADIPOSE TISSUE; APOPTOSIS; BIOENERGY; BROWN ADIPOSE TISSUE; CELL DIFFERENTIATION; CYTOLOGY; DRUG TARGETING; ENDOCRINE FUNCTION; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HISTOPATHOLOGY; HORMONE ACTION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LIPODYSTROPHY; MITOCHONDRIAL DNA DEPLETION; MITOCHONDRIAL TOXICITY; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION; TARGET CELL; WHITE ADIPOSE TISSUE;

ADIPOCYTES; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; HIV INFECTIONS; HIV-ASSOCIATED LIPODYSTROPHY SYNDROME; HUMANS; MITOCHONDRIA; SPAIN;

EID: 12844276053     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tips.2004.12.005     Document Type: Review

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