Compromising the unfolded protein response induces autophagy-mediated cell death in multiple myeloma cells

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Michallet, Anne Sophie ^a,b,c   Mondiere, Paul ^a,b   Taillardet, Morgan ^a,b   Leverrier, Yann ^a,b   Genestier, Laurent ^a,b   Defrance, Thierry ^a,b  

^a INSERM   (France)

^b UNIVERSITÉ DE LYON   (France)

^c CENTRE HOSPITALIER LYON SUD   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; APOPTOSOME; BAFILOMYCIN A1; CASPASE; CASPASE 3; CASPASE 9; CYTOCHROME C; DANSYLCADAVERINE; INOSITOL REQUIRING ENZYME 1; MICROTUBULE ASSOCIATED PROTEIN 1; MICROTUBULE ASSOCIATED PROTEIN 5; PANCREATIC ENDOPLASMIC RETICULUM KINASE LIKE ENDOPLASMIC RETICULUM KINASE; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; TUMOR PROTEIN; UNCLASSIFIED DRUG; SIGNAL PEPTIDE;

ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; BIOLOGICAL MONITORING; CELL DEATH; CELL NUCLEUS MEMBRANE; CONTROLLED STUDY; CYTOSOLIC FRACTION; CYTOTOXICITY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE SILENCING; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; LIGHT CHAIN; MITOCHONDRIAL MEMBRANE POTENTIAL; MULTIPLE MYELOMA; MYELOMA CELL; NUCLEOTIDE SEQUENCE; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN TARGETING; RNA INTERFERENCE; RNA SEQUENCE; TRANSMISSION ELECTRON MICROSCOPY; UNFOLDED PROTEIN RESPONSE; WESTERN BLOTTING; APOPTOSIS; CELL SURVIVAL; GENETICS; METABOLISM; MITOCHONDRION; PATHOLOGY; SECRETION; TUMOR CELL LINE;

MAMMALIA;

APOPTOSIS; AUTOPHAGY; CASPASES; CELL LINE, TUMOR; CELL SURVIVAL; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; GENE KNOCKDOWN TECHNIQUES; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MULTIPLE MYELOMA; RNA INTERFERENCE; UNFOLDED PROTEIN RESPONSE;

EID: 80054750084     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025820     Document Type: Article

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