Fitting the elementary rate constants of the p-gp transporter network in the hmdr1-mdck confluent cell monolayer using a particle swarm algorithm

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Agnani, Deep ^a,c   Acharya, Poulomi ^a,d   Martinez, Esteban ^a   Tran, Thuy Thanh ^b   Abraham, Feby ^b,e   Tobin, Frank ^b,f   Ellens, Harma ^b   Bentz, Joe ^a  

^a DREXEL UNIVERSITY   (United States)

^b GLAXOSMITHKLINE   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e MCKINSEY AND COMPANY   (United States)

^f Tobin Consulting LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPRENAVIR; DIGOXIN; GLYCOPROTEIN P; LOPERAMIDE; QUINIDINE; ADENOSINE TRIPHOSPHATE; CARBAMIC ACID DERIVATIVE; SULFONAMIDE;

ACCURACY; ACTIVE TRANSPORT; ALGORITHM; ANIMAL CELL; APICAL MEMBRANE; ARTICLE; BASOLATERAL MEMBRANE; CELL LINE; CELL SURFACE; CONCENTRATION RESPONSE; CONTROLLED STUDY; NONHUMAN; PARTICLE SWARM ALGORITHM; PROTEIN STRUCTURE; PROTEIN TRANSPORT; SURFACE PROPERTY; TRANSPORT KINETICS; ANIMAL; DOG; GENETICS; HUMAN; HYDROLYSIS; KINETICS; METABOLISM; TRANSPORT AT THE CELLULAR LEVEL;

ADENOSINE TRIPHOSPHATE; ALGORITHMS; ANIMALS; BIOLOGICAL TRANSPORT; CARBAMATES; CELL LINE; DIGOXIN; DOGS; HUMANS; HYDROLYSIS; KINETICS; LOPERAMIDE; P-GLYCOPROTEIN; SULFONAMIDES;

EID: 80054741770     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025086     Document Type: Article

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