Garlic-mode treatment effects on rat brain redox status

Journal of Medicinal Plant Research

Volumn 5, Issue 20, 2011, Pages 5094-5098

  Hamlaoui Gasmi, Sonia ^a   Limam, Nadia ^a   Mokni, Meherzia ^a   Limam, Ferid ^b   Aouani, Ezzedine ^b   Amri, Mohamed ^a   Marzouki, Lamjed ^a  

^a FACULTÉ DES SCIENCES DE TUNIS   (Tunisia)

^b CENTRE DE BIOTECHNOLOGIE DE BORJ CÉDRIA   (Tunisia)

Author keywords

Administration route; Antioxidant enzymes; Brain; Free iron; Garlic; Hydrogen peroxide; Lipoperoxidation; Redox status

Indexed keywords

CATALASE; GARLIC EXTRACT; HYDROGEN PEROXIDE; IRON; LACTATE DEHYDROGENASE; MALONALDEHYDE; PEROXIDASE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ABSORPTION; DRUG EFFECT; DRUG MEGADOSE; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; GARLIC; INTESTINE ABSORPTION; LIPID PEROXIDATION; MALE; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PROTEIN BLOOD LEVEL; RAT;

ALLIUM SATIVUM; RATTUS;

EID: 80054732080     PISSN: None     EISSN: 19960875     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Aebi H (1984). Catalase in vitro. Methods Enzymol., 105: 121-126.
2. Andrews NC (1999). Disorders of iron metabolism. New Engl. J. Med., 341: 1986-1995.
3. Bakri IM, Douglas CW (2005). Inhibitory effect of garlic extract on oral bacteria. Arch. Oral Biol., 50: 645-651.
4. Banerjee S, Maulik S (2002). Effect of garlic on cardiovascular disorders. Nutr. J., 1: 4.
5. Brankovic S, Radenkovic M, Kitic D (2011). Comparison of the hypotensive and bradycardic activity of ginkgo, garlic, and onion extracts. Clin. Exp. Hypertens, 33: 95-99.
6. Chance B, Maehly AC (1955). Assay of catalases and peroxidases. Methods Enzymol., 2: 764-817.
7. Chance B, Sies H, Boveris A (1979). Hydroperoxide metabolism in mammalian. Ann. Rev. Physiol., 59: 527-604.
8. Chauhan N (2006). Effect of aged garlic extract on APP processing and tau phosphorylation in Alzheimer's transgenic model Tg2576. J. Ethnopharmacol., 108: 385-394.
9. Draper HH, Hadley M (1990). A review of recent studies on the metabolism of exogenous and endogenous malondialdehyde. Xenobiotica, 20: 901-907.
10. Hamlaoui-Gasmi S, Mokni M, Aouani E, Amri M, Marzouki L (2011a). Modulation of hematological parameters by garlic based on route of administration in rat. J. Food Biochem., 35: 442-453.
11. Hamlaoui-Gasmi S, Mokni M, Limam F, Aouani E, Amri M, Marzouki L (2011b). Effect of the route of garlic treatment on modulation of erythrocytes and plasma redox status in rats In Press. J. Med. Plant Res., 5(12): 2508-2513.
12. Hamlaoui-Gasmi S, Limam N, Mokni M, Limam F, Aouani E, Amri M, Marzouki L (2011c). Effect of the route of garlic treatment on modulation of liver and spleen redox status in rats In Press. J. Med. Plants Res., 5(15): 3466-3474.
13. Hasani-Ranjbar S, Larijani B, Abdollahi M (2009). A systematic review of the potential herbal sources of future drugs effective in oxidantrelated diseases. Inflamm. Allergy Drug Targets, 8: 2-10.
14. Kulaksiz H, Fein E, Redecker P (2008). Pancreatic -cells express hepcidin and iron uptake regulatory peptide. J. Endocrinol., 197: 241-249.
15. Leardi A, Caraglia M, Selleri C (1998). Desferioxamine increases iron depletion and apoptosis induced by ara-C of human myeloid leukaemic cells. Br. J. Haematol., 102: 746-752.
16. Liu C, Wong P, Lii C (2006). Antidiabetic effect of garlic oil but not diallyl disulfide in rats with streptozotocin-induced diabetes. Food Chem. Toxicol., 44: 1377-1384.
17. Merle U, Fein E, Gehrke S (2007). The iron regulatory peptide hepcidin is expressed in the heart and regulated by hypoxia and inflammation. Endocrinol., 148: 2663-2668.
18. Misra HP, Fridovich I (1972). The role of superoxide anion in autoxidation of epinephrine and a simple assay for SOD. J. Biol. Chem., 247: 3170-3175.
19. Ohnishi ST, Barr JK (1978). A simple method of quantitating protein using the biuret and phenol reagent. Anal. Biochem., 86: 193-200.
20. Papanikolaou G, Tzilianos M, Christakis JL (2005). Hepcidin in iron overload disorders. Blood, 105: 4103-4105.
21. Pari L, Murugavel P (2007). Diallyl tetrasulfide improves cadmium induced alterations of acetylcholinesterase, ATPases and oxidative stress in brain of rats. Toxicol., 234: 44-50.
22. Park CH, Valore EV, Waring AJ, Ganz T (2001). Hepcidin, a urinary antimicrobial peptide synthesized in the liver. J. Biol. Chem., 276: 7806-7810.
23. Pedraza-Chaverri J, Medina-Campos O, Segoviano-Murillo S (2007). Effect of heating on peroxynitrite scavenging capacity of garlic. Food Chem. Toxicol., 45: 622-627.
24. Pigeon C, Ilyin G, Courseland B (2001). A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload. J. Biol. Chem., 276: 7811-7819.
25. Rahman K (2003). Garlic and aging: new insights into an old remedy. Ageing Res. Rev., 2: 39-56.
26. Rajasree C, Rajmohan T, Augusti K (2009). Antiatherogenic and antiperoxidative effects of garlic and soy proteins in alcohol fed rats. Indian J. Exp. Biol., 47: 169-175.
27. Sofiyan S, Muzamil A, Abdullah SA (2006). Behavioral and Histologic Neuroprotection of Aqueous Garlic Extract After Reversible Focal Cerebral Ischemia. J. Med. Food, 9(4): 537-544.
28. Steiner M, Li W (2001). Aged garlic extract, a modulator of cardiovascular risk factors: a dose-finding study of the effects of AGE on platelet functions. J. Nutr., 131: 980-984.
29. Syed M, Inamdar M, Asad M (2009). Effect of conventional antihypertensive drugs on hypolipidemic action of garlic in rats. Indian J. Exp. Biol., 47(3): 176-181.
30. Wang Q, Du F, Qian ZM (2008). Lipopolysaccharide induces a significant increase in expression of iron regulatory hormone hepcidin in the cortex and substantia nigra in rat brain. Endocrinol., 49: 3920-3925.