Macrophage migration inhibitory factor is involved in the pathogenesis of collagen type II-lnduced arthritis in mice

Journal of Immunology

Volumn 158, Issue 11, 1997, Pages 5514-5517

  Mikulowska, Anna ^a   Metz, Christine N ^b   Bucala, Richard ^b   Holmdahl, Rikard ^a  

^a LUND UNIVERSITY   (Sweden)

^b PICOWER INST FOR MEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; MACROPHAGE MIGRATION INHIBITION FACTOR;

ANIMAL; ARTHRITIS; ARTICLE; CHEMICALLY INDUCED DISORDER; IMMUNOLOGY; MOUSE; PATHOLOGY;

ANIMALS; ARTHRITIS; COLLAGEN; MACROPHAGE MIGRATION-INHIBITORY FACTORS; MICE;

EID: 0031154718     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. David, J. 1966. Delayed hypersensitivity in vitro: its mediation by cell-free substances formed by lymphoid cell-antigen interaction. Proc. Natl. Acad. Sci. USA 56:72.
2. Nathan, C., H. Remold, and J. David. 1973. Characterization of lymphocyte factor which alters macrophage function. J. Exp. Med. 133:1356.
3. Churchill, W., W. Piessens, C. Sulis, and J. David. 1975. Macrophages activated as suspension cultures with lymphocyte mediators devoid of antigen become cytotoxic for tumor cells. J. Immunol. 115:781.
4. Bacher, M., C. Metz, T. Calandra, K. Mayer, J. Chesney, M. Lohoff, D. Gemsa, T. Donelly, and R. Bucala. 1996. An essential regulatory role for macrophage migration inhibitory factor in T-cell activation. Proc. Natl. Acad. Sci. USA 93: 7849.
5. Bernhagen, J., T. Calandra, A. Cerami, and R. Bucala. 1994. Macrophage migration inhibitory factor is a neuroendocrine mediator of endotoxaemia. Trends Microbiol. 2:198.
6. Calandra, T., J. Bernhagen, C. N. Metz, L. A. Spiegel, M. Bacher, T. Donnelly, A. Cerami, and R. Bucala. 1995. MIF as a glucocorticoid-induced modulator of cytokine production. Nature 376:68.
7. Yanni, G., A. Whelan, F. Conleth, and B. Bresnihan. 1994. Synovial tissue macrophages and joint erosion in rheumatoid arthritis. Ann. Rheum. Dis. 53:39.
8. van Lent, P., A. Holthuysen, L. van den Bresselaar, N. van Roojen, L. van den Putte, and W. van den Berg. 1995. Role of macrophage-like synovial lining cells in localization and expression of experimental arthritis. Scand. J. Rheumatol. 24(Suppl. 101):83.
9. Michaelsson, E., M. Holmdahl, A. Engstrom, H. Burkhardt, A. Scheynius, and R. Holmdahl. 1995. Macrophages, but not dendritic cells, present collagen to T cells. Eur. J. Immunol. 25:2234.
10. Zvifler, N. 1995. Macrophage and the synovial lining. Scand. J. Rheumatol. 24(Suppl. 101):67.
11. Holmdahl, R., M. Andersson, T. J. Goldschmidt, K. Gustafsson, L. Jansson, and J. A. Mo. 1990. Type II collagen autoimmunity in animals and provocations leading to arthritis. Immunol. Rev. 118:193.
12. Trentham, D., A. Townes, and A. Kang. 1977. Autoimmunity to type II collagen: an experimental model of arthritis. J. Exp. Med. 146:857.
13. Bernhagen, J., T. Calandra, R. A. Mitchell, S. B. Martin, K. J. Tracey, W. Voelter, K. R. Manogue, A. Cerami, and R. Bucala. 1993. MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia. Nature 365:756.
14. Bernhagen, J., M. Bacher, T. Calandra, C. Metz, B. Doty, T. Donnelly, and R. Bucala. 1996. An essential role for macrophage migration inhibitory factor in the tuberculin delayed-type hypersensitivity reaction. J. Exp. Med. 183:277.
15. Miller, E. 1972. Structural studies on cartilage collagen employing limited cleavage and solubilization with pepsin. Biochemistry 11:4903.
16. Holmdahl, R., L. Klareskog, M. Andersson, and C. Hansen. 1986. High antibody response to autologous type II collagen is restricted to H-2q. Immunogenetics 24:84.
17. Kühn, R., K. Rajewsky, and W. Müller. 1991. Generation and analysis of interleukin-4 deficient mice. Science 254:707.
18. Guery, J. C., F. Galbiati, S. Smiroldo, and L. Adorini. I996. Selective development of T helper (Th)2 cells induced by continuous administration of low dose soluble proteins to normal and beta(2)-microglobulin-deficient BALB/c mice. J. Exp. Med. 183:485.
19. Chu, C. Q., and M. Londei. 1996. Induction of Th2 cytokines and control of collagen-induced arthritis by nondepleting anti-CD4 Abs. J. Immunol. 157:2685.
20. Andersson, M., and R. Holmdahl. 1990. Analysis of type II collagen reactive T cell in the mouse: different regulation of autoreactive versus non-autoreactive anti-type II collagen T cells in the DBA/1 mouse. Eur. J. Immunol. 20:1061.
21. Jansson, L., A. Mattsson, R. Mattsson, and R. Holmdahl. 1990. Estrogen induced suppression of collagen arthritis. V. Physiological level of estrogen in DBA/1 mice is therapeutic on established arthritis, suppresses anti-type II collagen T-cell dependent immunity and stimulates polyclonal B-cell activity. J. Autoimmun. 3:257.
22. Calandra, T., J. Bernhagen, R. A. Mitchell, and R. Bucala. 1994. The macrophage is an important and previously unrecognized source of macrophage migration inhibitory factor. J. Exp. Med. 179:1895.