Senescent phenotype of trabecular meshwork cells displays biomarkers in primary open-angle glaucoma

Current Molecular Medicine

Volumn 11, Issue 7, 2011, Pages 528-552

  Babizhayev, M A ^a,b   Yegorov, Y E ^c  

^a Innovative Vision Products Incorporated   (United States)

^b MOSCOW HELMHOLTZ RESEARCH INSTITUTE OF EYE DISEASES   (Russian Federation)

^c ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

Author keywords

Accelerated senescence and telomere attrition of trabecular meshwork cells; Accumulation of extracellular matrix; An increased outflow resistance and elevated intraocular pressure; Biomarkers; Carnosine related compounds; Loss of trabecular meshwork cells; Oxidative stress induced damages of trabecular meshwork; Primary open angle glaucoma; Primary open angle glaucoma therapy; Trabecular meshwork endothelium cells

Indexed keywords

ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETAXOLOL; BIOLOGICAL MARKER; BRIMONIDINE; BRIMONIDINE PLUS TIMOLOL; BRINZOLAMIDE; CARBONATE DEHYDRATASE INHIBITOR; CARNOSINE; DEXAMETHASONE; DORZOLAMIDE; DORZOLAMIDE PLUS TIMOLOL; EYE DROPS; HYDROGEN PEROXIDE; LATANOPROST; LIPID PEROXIDE; MESSENGER RNA; MONOCLONAL ANTIBODY; MYOSIN; N ACETYLCARNOSINE; PHOSPHATIDYLSERINE; PROSTAGLANDIN F2 ALPHA; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; TIMOLOL; TRAVOPROST; UNCLASSIFIED DRUG;

ACTIN FILAMENT; APOPTOSIS; AQUEOUS HUMOR; ARTICLE; AUTOPHAGY; CELL DEATH; CELL LOSS; CELL POPULATION; CELL PROLIFERATION; CILIARY MUSCLE; DISEASE ASSOCIATION; DISEASE COURSE; DNA FRAGMENTATION; ELECTRON MICROSCOPY; ENDOTHELIUM; EX VIVO STUDY; FAMILY HISTORY; GLAUCOMA; HISTOCHEMISTRY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INTRAOCULAR HYPERTENSION; INTRAOCULAR PRESSURE; OPEN ANGLE GLAUCOMA; OPTIC NERVE; OXIDATIVE STRESS; PHENOTYPE; PSEUDOEXFOLIATION; REGRESSION ANALYSIS; RETINA GANGLION CELL; SCHLEMM CANAL; SCLERECTOMY; TRABECULAR MESHWORK; TRABECULECTOMY; UNSPECIFIED SIDE EFFECT; VISUAL IMPAIRMENT;

EID: 80053983088     PISSN: 15665240     EISSN: 18755666     Source Type: Journal    
DOI: 10.2174/156652411800615126     Document Type: Article

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