Interendothelial junctions in normal human schlemm's canal respond to changes in pressure

Investigative Ophthalmology and Visual Science

Volumn 38, Issue 12, 1997, Pages 2460-2468

  Ye, Wen ^a   Gong, Haiyan ^a   Sit, Arthur ^b   Johnson, Mark ^b   Freddo, Thomas F ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AQUEOUS HUMOR; ARTICLE; CELL JUNCTION; ENDOTHELIUM CELL; FREEZE FRACTURE; HUMAN; HUMAN CELL; NORMAL HUMAN; PERFUSION PRESSURE; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SCHLEMM CANAL; TIGHT JUNCTION;

AGED; AGED, 80 AND OVER; AQUEOUS HUMOR; ENDOTHELIUM; FREEZE FRACTURING; HUMANS; INTERCELLULAR JUNCTIONS; MIDDLE AGED; PERFUSION; PRESSURE; SCLERA; TIGHT JUNCTIONS; TISSUE FIXATION; TRABECULAR MESHWORK;

EID: 0030729742     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Garron LK, Feeney ML, Hogan MJ, McEwen WK. Electron microscopic studies of the human eye. Am J Ophthalmol. 1958;40:27-35.
2. Holmberg A. The fine structure of the inner wall of Schlemm's canal. Arch Ophthalmol. 1959;62:956-958.
3. Tripathi RC. Ultrastructure of Schlemm's canal in relation to aqueous outflow. Exp Eye Res. 1968;7:335-341.
4. Bill A, Svedbergh B. Scanning electron microscopic studies of the trabecular meshwork and the canal of Schlemm: An attempt to locate the main resistance to outflow of aqueous humor in man. Acta Ophthalmol. 1972;50:295-320.
5. Epstein DL, Rohen JW. Morphology of the trabecular meshwork and inner-wall endothelium after cat-ionized ferritin perfusion in the monkey eye. Invest Ophthalmol Vis Sci. 1991;32(1):160-171.
6. Ethier CR, Sit AJ, Coloma FM, Johnson M: Two populations of pores of the inner wall endothelium of Schlemm's canal. Invest Ophthalmol Vis Sci. (In press).
7. Raviola G, Raviola E. Paracellular route of aqueous outflow in the trabecular meshwork and canal of Schlemm. Invest Ophthalmol Vis Sci. 1981;21(part 1):52-72.
8. Okinami S, Matsumura M, Ohkuma M. Freeze-fractured replica of Schlemm's canal and the trabecular meshwork in the primate. Graefes Arch Clin Exp Ophthalmol. 1981;217:17-26.
9. Bhatt K, Gong H, Freddo T. Freeze-fracture studies of interendothelial junctions in the angle of the human eye. Invest Ophthalmol Vis Sci. 1995;36:1379-1389.
10. Johnston MA, Grant WM. Pressure-dependent changes in structures of the aqueous outflow system of human and monkey eyes. Am J Ophthalmol. 1973;75: 365-383.
11. Moses RA. The effect of intraocular pressure on resistance to outflow. Surv Ophthalmol. 1977;22:88-100.
12. Grierson I, Lee WR. The fine structure of the trabecular meshwork at graded levels of intraocular pressure. 1. Pressure effects within the near-physiological range (8-30 mm Hg). Exp Eye Res. 1975;20:505-521.
13. Grierson I, Lee WR. The fine structure of the trabecular meshwork at graded levels of intraocular pressure. 2. Pressure outside the physiological range (0 and 50 mm Hg). Exp Eye Res. 1975;20:523-530.
14. Grierson I, Lee WR. Pressure-induced changes in the ultrastructure of the endothelium lining Schlemm's canal. Am J Ophthalmol. 1975;80:863-884.
15. Ohnishi Y, Tanaka M. Effects of pilocarpine and paracentesis on occluding junctions between the nonpigmented ciliary epithelial cells. Exp Eye Res. 1981; 32:635-647.
16. Whale MD, Grodzinsky AJ, Johnson M. The effect of aging and pressure on the specific hydraulic conductivity of the aortic wall. Biorheolagy. 1996;33:17-44.
17. Claude P, Goodenough D. Fracture faces of zonulae occludentes from "tight" and "leaky" epithelia. J Cell Biol. 1973;58:390-400.
18. Claude P. Morphological factors influencing transepithelial permeability: A model for the resistance of the zonula occludens. J Membr Biol. 1978;39:219-232.
19. Freddo TF. Intercellular junctions of the ciliary epithelium in anterior uveitis. Invest Ophthalmol Vis Sci. 1987;28:320-329.
20. Freddo TF, Sacks-Wilner R. Interendothelial junctions of the rabbit iris vasculature in anterior uveitis. Invest Ophthalmol Vis Sci. 1989;30:1104-1111.
21. ++ dependent disassembly and reassembly of occluding junctions in guinea pig pancreatic acinar cells. Effect of drugs. J Cell Biol. 1978;79:156-172.
22. Tripathi RC. Mechanism of the aqueous outflow across the trabecular wall of Schlemm's canal. Exp Eye Res. 1971;11:116-121.
23. Fink AI, Felix MD, Fletcher RC. Schlemm's canal and adjacent structures in glaucomatous patients. Am J Ophthalmol. 1972;74:893-906.
24. Grierson I, Johnson NF. The post-mortem vacuoles of Schlemm's canal. Graefes Archiv Ophthalmologie 1981; 215:249-264.
25. Tripathi RC. The functional morphology of the outflow systems of ocular and cerebrospinal fluids. Exp Eye Res. 1977;25(suppl):65-116.