Senescence in cultured trabecular meshwork cells

British Journal of Ophthalmology

Volumn 91, Issue 6, 2007, Pages 808-811

  Yamazaki, Yukari ^a   Matsunaga, Hiroshi ^a   Nishikawa, Maki ^a   Ando, Akira ^a   Kaneko, Shiho ^a   Okuda, Koji ^a   Wada, Mitsumasa ^a   Ito, Seiji ^a   Matsumura, Miyo ^a  

^a KANSAI MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; FLUORESCEIN; LOW DENSITY LIPOPROTEIN; TRYPSIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL MIGRATION; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; ENZYME ACTIVATION; IN VITRO STUDY; NONHUMAN; OPEN ANGLE GLAUCOMA; POPULATION; PRIORITY JOURNAL; SENESCENCE; SOUTHERN BLOTTING; SWINE; TERMINAL SEQUENCE; TRABECULAR MESHWORK; UPREGULATION;

ANIMALS; BETA-GALACTOSIDASE; CELL AGING; CELL CULTURE TECHNIQUES; CELL PROLIFERATION; CELL SHAPE; LIPOPROTEINS, LDL; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; SWINE; TELOMERE; TISSUE CULTURE TECHNIQUES; TRABECULAR MESHWORK; UP-REGULATION;

EID: 34249780529     PISSN: 00071161     EISSN: None     Source Type: Journal    
DOI: 10.1136/bjo.2006.108423     Document Type: Article

References (20)

1. Hayflick L. Limited in vitro lifetime of human diploid cell strains. Exp Cell Res 1965;37:614-36.
2. Campisi J. Replicative senescence: an old lives' tale? Cell 1996;84:497-500.
3. Goldstein S. Increased procoagulant activity in cultured fibroblasts from progeria and Werner's syndromes of premature ageing. Nature 1976;260:711-13.
4. Goldstein S. Studies on age-related diseases in cultured skin fibroblasts. J Invest Dermatol 1979;73:19-23.
5. Norwood TH, Hoehn H, Salk D, et al. Cellular aging in Werner's syndrome: a unique phenotype? J Invest Dermatol 1979;73:92-6.
6. Alvarado J, Murphy C, Polansky J, et al. Age-related changes in trabecular meshwork cellularity. Invest Ophthalmol Vis Sci 1981;21:714-27.
7. Alvarado J, Murphy C, Juster R. Trabecular meshwork cellularity in primary open-angle glaucoma and nonglaucomatous normals. Ophthalmology 1984;91:564-79.
8. Tripathi RC. Pathologic anatomy of the outflow pathway of aqueous humor in chronic simple glaucoma. Exp Eye Res 1977;25(Suppl):403- 7.
9. Lütjen-Drecoll E, Rittig M, Rauterberg J, et al. Immunomicroscopical study of type VI collagen in the trabecular meshwork of normal and glaucomatous eyes. Exp Eye Res 1989;48:139-47.
10. Matsunaga H, Handa JT, Aotaki-Keen A, et al. β-Galactosidase histochemistry and telomere loss in senescent retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 1999;40:197- 202.
11. Tripathi BJ, Tripathi RC. Neural crest origin of human trabecular meshwork and its implications for the pathogenesis of glaucoma. Am J Ophthalmol 1989;107:583-90.
12. Buller C, Johnson DH, Tschumper RC. Human trabecular meshwork phagocytosis. Invest Ophthalmol Vis Sci 1990;31:2156-63.
13. Calthorpe CM, Grierson I. Fibronectin induces migration of bovine trabecular meshwork cells in vitro. Exp Eye Res 1990;51:39-48.
14. Tripathi BJ, Li T, Li J, et al. Age-related changes in trabecular cells in vitro. Exp Eye Res 1997;64:57-66.
15. Chang IL, Elner G, Yue YJ, et al. Expression of modified low-density lipoprotein receptors by trabecular meshwork cells. Curr Eye Res 1991;10:1101-12.
16. Dimri GP, Lee X, Basile G, et al. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci USA 1995;92:9363-7.
17. Allsopp RC, Vaziri H, Patterson C, et al. Telomere length predicts replicative capacity of human fibroblasts. Proc Natl Acad Sci USA 1992;89:10114-18.
18. Okuda K, Bardeguez A, Gardner JP, et al. Telomere length in the newborn. Pediatr Res 2002;52:377-81.
19. Takeda K, Gosiewska A, Peterkofsky B. Similar, but not identical, modulation of expression of extracellular matrix components during in vitro and in vivo aging of human skin fibroblasts. J Cell Physiol 1992;153:450-9.
20. Tombran-Tink J, Shivaram SM, Chader GJ, et al. Expression, secretion, and age-related downregulation of pigment epithelium-derived factor, a serpin with neurotrophic activity. J Neurosci 1995;15:4992-5003.