Time-course activities of Oct1, Mrp3, and cytochrome P450s in cultures of cryopreserved rat hepatocytes

European Journal of Pharmaceutical Sciences

Volumn 44, Issue 3, 2011, Pages 427-436

  Jacobsen, Jacob Kramer ^a   Jensen, Bente ^b   Skonberg, Christian ^c   Hansen, Steen Honoré ^a   Badolo, Lassina ^b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b H LUNDBECK A S   (Denmark)

^c NOVO NORDISK A S   (Denmark)

Author keywords

CYPs; Functional activity; Hepatocyte cultures; Mrp3; Oct1; Transport proteins

Indexed keywords

AMFEBUTAMONE; BUFURALOL; CYTOCHROME P450 2B1; CYTOCHROME P450 2D1; CYTOCHROME P450 3A1; MESSENGER RNA; MIDAZOLAM; MULTIDRUG RESISTANCE PROTEIN 3; OCTAMER TRANSCRIPTION FACTOR 1; TAUROCHOLIC ACID;

ANIMAL CELL; ARTICLE; CELL ISOLATION; CRYOPRESERVATION; IN VITRO STUDY; LIVER CELL; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TRANSPORT; RAT;

ANIMALS; CATECHOLAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; CELL CULTURE TECHNIQUES; CELLS, CULTURED; CRYOPRESERVATION; CYTOCHROME P-450 ENZYME SYSTEM; HEPATOCYTES; MALE; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; POLYMERASE CHAIN REACTION; RATS; RATS, SPRAGUE-DAWLEY; SUBSTRATE SPECIFICITY; TIME FACTORS; XENOBIOTICS;

EID: 80053929816     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2011.09.001     Document Type: Article

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