Instillation of six different ultrafine carbon particles indicates a surface area threshold dose for acute lung inflammation in mice

Environmental Health Perspectives

Volumn 114, Issue 3, 2006, Pages 328-333

  Stoeger, Tobias ^a,b   Reinhard, Claudia ^a   Takenaka, Shinji ^a   Schroeppel, Andreas ^a   Karg, Erwin ^a   Ritter, Baerbel ^a   Heyder, Joaquim ^a   Schulz, Holger ^a  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b NONE   (Germany)

Author keywords

Air pollution; Dose response relation; Nanoparticles; Particle toxicology; Particulate matter; Specific surface area; Ultrafine particles

Indexed keywords

CARBON;

AIR POLLUTION; ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ARTICLE; BODY SURFACE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; DOSE RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; EXHAUST GAS; FEMALE; HEALTH HAZARD; INFLAMMATORY CELL; LUNG LAVAGE; MORBIDITY; MORTALITY; MOUSE; MOUSE STRAIN; NANOPARTICLE; NONHUMAN; PARTICLE SIZE; PARTICULATE MATTER; PNEUMONIA; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RISK ASSESSMENT; RISK FACTOR; SOOT; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CARBON; FEMALE; INFLAMMATION; INTERLEUKIN-1; LUNG; MICE; MICE, INBRED BALB C; MONOKINES; NEUTROPHILS; PARTICLE SIZE; SURFACE PROPERTIES; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA;

EID: 33644746349     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.8266     Document Type: Article

References (51)

1. Bateson TF, Schwartz J. 2001. Selection bias and confounding in case-crossover analyses of environmental time-series data. Epidemiology 12:654-661.
2. 2 induce generation of lipid mediators in alveolar macrophages. Environ Health Perspect 109(suppl 4):613-618.
3. Beck-Speier I, Dayal N, Karg E, Maier KL, Schumann G, Schulz H, et al. 2005. Oxidative stress and lipid mediators induced in alveolar macrophages by ultrafine particles. Free Radic Biol Med 8:1080-1092.
4. Brand P, Ruob K, Gebhard J. 1992. Technical note: performance of a mobile aerosol spectrometer for in situ characterisation of an environmental aerosol in Frankfurt city. Atmos Environ 26A:2451-2457.
5. Brauer M, Avila-Casado C, Fortoul TI, Vedal S, Stevens B, Churg A. 2001. Air pollution and retained particles in the lung. Environ Health Perspect 109:1039-1043.
6. Brown DM, Stone V, Findlay P, MacNee W, Donaldson K. 2000. Increased inflammation and intracellular calcium caused by ultrafine carbon black is independent of transition metals or other soluble components. Occup Environ Med 57:685-691.
7. Brown RH, Walters DM, Greenberg ES, Mitzner W. 1999. A method of endotracheal intubation and pulmonary functional assessment for repeated studies in mice. J Appl Physiol 87:2362-2365.
8. Brunauer S, Emmett PH, Teller E. 1938. Absorption of gases in multimolecular layers. J Am Chem Soc 60:309-319.
9. Cassinelli ME, O'Connor PF, eds. 1998. NIOSH Method 5040. In: NIOSH Manual of Analytical Methods (NMAM), Second Supplement to NMAM. 4th ed. DHHS (NIOSH) Publication No. 94-113. Cincinnati, OH:National Institute for Occupational Safety and Health. Available: http://www.cdc.gov/niosh/nmam/pdfs/5040.pdf [accessed 22 December 2005].
10. Chang CC, Chiu HF, Wu YS, Li YC, Tsai ML, Shen CK, et al. 2005. The induction of vascular endothelial growth factor by ultra-fine carbon black contributes to the increase of alveolarcapillary permeability. Environ Health Perspect 113:454-460.
11. Daigle CC, Chalupa DC, Gibb FR, Morrow PE, Oberdorster G, Utell MJ, et al. 2003. Ultrafine particle deposition in humans during rest and exercise. Inhal Toxicol 15:539-552.
12. Dick CA, Brown DM, Donaldson K, Stone V. 2003. The role of free radicals in the toxic and inflammatory effects of four different ultrafine particle types. Inhal Toxicol 15:39-52.
13. 10). Free Radic Biol Med 34:1369-1382.
14. Driscoll KE, Carter JM, Howard BW, Hassenbein DG, Pepelko W, Baggs RB, et al. 1996. Pulmonary inflammatory, chemokine, and mutagenic responses in rats after subchronic inhalation of carbon black. Toxicol Appl Pharmacol. 136:372-380.
15. Ebelt S, Brauer M, Cyrys J, Tuch T, Kreyling WG, Wichmann HE, et al. 2001. Air quality in postunification Erfurt, East Germany: associating changes in pollutant concentrations with changes in emissions. Environ Health Perspect 109:325-333.
16. Ferin J, Oberdorster G, Penney DP. 1992. Pulmonary retention of ultrafine and fine particles in rats. Am J Respir Cell Mol Biol 6:535-542.
17. Frampton MW, Utell MJ, Zareba W, Oberdorster G, Cox C, Huang LS, et al. 2004. Effects of exposure to ultrafine carbon particles in healthy subjects and subjects with asthma. Res Rep Health Eff Inst 126:1-47.
18. Gilmour MI, O'Connor S, Dick CA, Miller CA, Linak WP. 2004. Differential pulmonary inflammation and in vitro cytotoxicity of size-fractionated fly ash particles from pulverized coal combustion. J Air Waste Manag Assoc 54:286-295.
19. Hahn FF, Newton GJ, Bryant PL. 1977. In vitro phagocytosis of respirable-sized monodisperse particles by alveolar macrophages. In: Pulmonary Macrophages and Epithelial Cells: Proceedings of the Sixteenth Annual Hanford Biology Symposium, September 1976, Richland, WA (Sanders C, Schneider R, Dagle G, Ragan H, eds). ERDA Symposium Series 43. Oak Ridge, TN:Energy Research and Development Administration, 424-436.
20. Hughes LS, Cass GR, Gone J, Ames M, Olmez I. 1998. Physical and chemical characterization of atmospheric ultrafine particles in the Los Angeles area. Environ Sci Technol 32:1153-1161.
21. Kreyling WG, Tuch T, Peters A, Pitz M, Heinrich J, Stolzel M, et al. 2003. Diverging long-term trends in ambient urban particle mass and number concentrations associated with emission changes caused by the German unification. Atmos Environ 37:3841-3848.
22. Lambert AL, Trasti FS, Mangum JB, Everitt JI. 2003. Effect of preexposure to ultrafine carbon black on respiratory syncytial virus infection in mice. Toxicol Sci 72:331-338.
23. Leong BK, Coombs JK, Sabaitis CP, Rop DA, Aaron CS. 1998. Quantitative morphometric analysis of pulmonary deposition of aerosol particles inhaled via intratracheal nebulization, intratracheal instillation or nose-only inhalation in rats. J Appl Toxicol 18:149-160.
24. Li N, Kim S, Wang M, Froines J, Sioutas C, Nel A. 2002. Use of a stratified oxidative stress model to study the biological effects of ambient concentrated and diesel exhaust particulate matter. Inhal Toxicol 14:459-486.
25. Li XY, Brown D, Smith S, MacNee W, Donaldson K. 1999. Shortterm inflammatory responses following intratracheal instillation of fine and ultrafine carbon black in rats. Inhal Toxicol 11:709-731.
26. Lison D, Lardot C, Huaux F, Zanetti G, Fubini B. 1997. Influence of particle surface area on the toxicity of insoluble manganese dioxide dusts. Arch Toxicol 71:725-729.
27. MacNee W, Donaldson K. 2000. How can ultrafine particles be responsible for increased mortality? Monaldi Arch Chest Dis 55:135-139.
28. Nicklas W, Baneux P, Boot R, Decelle T, Deeny AA, Fumanelli M, et al. 2002. Recommendations for the health monitoring of rodent and rabbit colonies in breeding and experimental units. Lab Anim 36:20-42.
29. Oberdorster G. 1996. Significance of particle parameters in the evaluation of exposure-dose-response relationships of inhaled particles. Inhal Toxicol 8:S73-S89.
30. Oberdorster G. 2001. Pulmonary effects of inhaled ultrafine particles. Int Arch Occup Environ Health 74:1-8.
31. Oberdorster G. 2002. Toxicokinetics and effects of fibrous and nonfibrous particles. Inhal Toxicol 14:29-56.
32. Oberdorster G, Finkelstein JN, Johnston C, Gelein R, Cox C, Baggs R, et al. 2000. Acute pulmonary effects of ultrafine particles in rats and mice. Res Rep Health Eff Inst 96:5-74.
33. Peters A, Wichmann HE, Tuch T, Heinrich J, Heyder J. 1997. Respiratory effects are associated with the number of ultra-fine particles. Am J Respir Crit Care Med 155:1376-1383.
34. Pope CA III. 2000. Epidemiology of fine particulate air pollution and human health: biologic mechanisms and who's at risk? Environ Health Perspect 108:713-723.
35. Renwick LC, Brown D, Clouter A, Donaldson K. 2004. Increased inflammation and altered macrophage chemotactic responses caused by two ultrafine particle types. Occup Environ Med 61:442-447.
36. Roth C, Ferron GA, Karg E, Lentner B, Schumann G. 2004. Generation of ultrafine particles by spark discharging. Aerosol Sci Technol 38:228-235.
37. Schroeppel A, Lintelmann J, Karg E, Ferron GA. 2003. Physical and chemical characterisation of particles produced by a flame soot aerosol generator (CAST) [Abstract]. J Aerosol Sci 34:S1253-S1254.
38. Schwartz J, Laden F, Zanobetti A. 2002. The concentration-response relation between PM(2.5) and daily deaths. Environ Health Perspect 110:1025-1029.
39. Schwartz J, Zanobetti A. 2000. Using meta-smoothing to estimate dose-response trends across multiple studies, with application to air pollution and daily death. Epidemiology 11:666-672.
40. Seaton A, MacNee W, Donaldson K, Godden D. 1995. Particulate air pollution and acute health effects. Lancet 345:176-178.
41. Semmler M, Seitz J, Erbe F, Mayer P, Heyder J, Oberdorster G, et al. 2004. Long-term clearance kinetics of inhaled ultrafine insoluble iridium particles from the rat lung, including transient translocation into secondary organs. Inhal Toxicol 16:453-459.
42. Shaw DJ. 1992. Colloid and Surface Chemistry, 4th ed. Oxford, UK:Butterworth Heinemann Ltd, 235.
43. Shi T, Schins RP, Knaapen AM, Kuhlbusch T, Pitz M, Heinrich J, et al. 2003. Hydroxyl radical generation by electron paramagnetic resonance as a new method to monitor ambient particulate matter composition. J Environ Monit 5:550-556.
44. Stoeger T, Reinhard C, Ritter B, Karg E, Schröppel A, Heyder J, et al. 2004. Comparison of the inflammatory effects of five different particles in BALB/cJ mice. In: Effects of Air Contaminants on the Respiratory Tract - Interpretations from Molecules to Meta Analysis (Heinrich U, ed). Stuttgart, Germany:Fraunhofer IRB Verlag, 75-84.
45. Stone KC, Mercer RR, Gehr P, Stockstill B, Crapo JD. 1992. Allometric relationships of cell numbers and size in the mammalian lung. Am J Respir Cell Mol Biol 6:235-243.
46. Tran CL, Buchanan D, Cullen RT, Searl A, Jones AD, Donaldson K. 2000. Inhalation of poorly soluble particles. II. Influence of particle surface area on inflammation and clearance. Inhal Toxicol 12:1113-1126.
47. Utell MJ, Frampton MW. 2000. Acute health effects of ambient air pollution: the ultrafine particle hypothesis. J Aerosol Med 13:355-359.
48. Wichmann HE, Spix C, Tuch T, Wolke G, Peters A, Heinrich J, et al. 2000. Daily mortality and fine and ultrafine particles in Erfurt, Germany. Part I. Role of particle number and particle mass. Res Rep Health Eff Inst 98:5-86.
49. Yanagisawa R, Takano H, Inoue K, Ichinose T, Sadakane K, Yoshino S, et al. 2003. Enhancement of acute lung injury related to bacterial endotoxin by components of diesel exhaust particles. Thorax 58:605-612.
50. Yokota S, Fujimori O, eds. 1992. Methods of Immunogold Staining. Tokyo, Japan:Soft Science Publications, 29-47.
51. Zhu Y, Hinds WC, Kim S, Sioutas C. 2002. Concentration and size distribution of ultrafine particles near a major highway. J Air Waste Manag Assoc 52:1032-1042.