Acamprosate-responsive brain sites for suppression of ethanol intake and preference

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 301, Issue 4, 2011, Pages

  Brager, Allison ^a   Prosser, Rebecca A ^b   Glass, J David ^a  

^a KENT STATE UNIVERSITY   (United States)

^b UNIVERSITY OF TENNESSEE   (United States)

Author keywords

Circadian rhythm; Mouse; mPer2 clock gene; Relapse; Reward

Indexed keywords

ACAMPROSATE; ALCOHOL; MUTANT PROTEIN; PER2 PROTEIN; WATER;

ALCOHOL CONSUMPTION; ALCOHOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CIRCADIAN RHYTHM; CONTROLLED STUDY; DRINKING BEHAVIOR; DRUG BINDING SITE; DRUG IMPLANT; FLUID INTAKE; GENICULATE NUCLEUS; HIPPOCAMPUS; LOCOMOTION; MALE; MOUSE; NONHUMAN; NUCLEUS ACCUMBENS; PEDUCULOPONTINE TEGMENTUM; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; RELAPSE; SUPRACHIASMATIC NUCLEUS; TEGMENTUM; VENTRAL TEGMENTUM; WILD TYPE;

ALCOHOL DETERRENTS; ALCOHOL DRINKING; ANIMALS; BRAIN; CIRCADIAN RHYTHM; DRINKING; FOOD PREFERENCES; HIPPOCAMPUS; MALE; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MODELS, ANIMAL; MOTOR ACTIVITY; NUCLEUS ACCUMBENS; PEDUNCULOPONTINE TEGMENTAL NUCLEUS; PERIOD CIRCADIAN PROTEINS; SUPRACHIASMATIC NUCLEUS; TAURINE; VENTRAL TEGMENTAL AREA;

EID: 80053635834     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00179.2011     Document Type: Article

References (66)

1. 2+channels in cultured rat mesencephalic neurones. Naunyn Schmiedebergs Arch Pharmacol 362: 440-443, 2000.
2. Blednov YA, Harris RA. Metabotropic glutamate receptor 5 (mGluR5) regulation of ethanol sedation, dependence, and consumption: relationship to acamprosate actions. Int J Neuropsychopharmacol 11: 775-793, 2008.
3. Brager AJ, Prosser RA, Glass JD. Circadian and acamprosate modulation of elevated ethanol drinking in mPer2 clock gene mutant mice. Chronobiol Int In press.
4. Brager AJ, Ruby CL, Prosser RA, Glass JD. Chronic ethanol disrupts circadian photic entrainment and impairs daily locomotor activity in the mouse. Alcohol Clin Exp Res 34: 1266-1273, 2010.
5. Brager AJ, Ruby CL, Prosser RA, Glass JD. Acute ethanol impairs photic and serotonergic phase-resetting in the mouse. Alcohol Clin Exp Res. In press.
6. Cano-Cebrián MJ, Zornoza-Sabina T, Guerri C, Polache A, Granero L. Local acamprosate modulates dopamine release in the rat nucleus accumbens through NMDA receptors: an in vivo microdialysis study. Naunyn Schmiedebergs Arch Pharmacol 367: 119-125, 2003.
7. Card JP, Moore RY. Ventral lateral geniculate nucleus efferent to the rat suprachiasmatic nucleus exhibit avian pancreatic polypeptide-like immunoreactivity. J Comp Neurol 206: 390-396, 1982.
8. Chau P, Lidö-Hölfödt H, Löf E, Söderpalm B, Ericson M. Glycine receptors in the nucleus accumbens involved in the ethanol intakereducing effect of acamprosate. Alcohol Clin Exp Res 34: 39-45, 2010.
9. Chau P, Stomberg R, Fagerberg A, Söderpalm B, Ericson M. Glycine receptors involved in acamprosate's modulation of accumbal dopamine levels: an in vivo microdialysis study. Alcohol Clin Exp Res 34: 32-38, 2010.
10. Chaudhri N, Sahuque LL, Cone JJ, Janak PH. Reinstated ethanolseeking in rats is modulated by environmental context and requires the nucleus accumbens core. Eur J Neurosci 28: 2288-2298, 2008.
11. Cowen MS, Adams C, Kraehenbuehl T, Vengeliene V, Lawrence AJ. The acute anti-craving effect of acamprosate in alcohol-preferring rats is associated with modulation of the mesolimbic dopamine system. Addict Biol 10: 233-242, 2005.
12. DeCoursey PJ, Krulas JR, Mele G, Holley DC. Circadian performance of suprachiasmatic nuclei (SCN)-lesioned antelope ground squirrels in a desert enclosure. Physiol Behav 62: 1099-1108, 1997.
13. De Witte P, Littleton J, Parot P, Koob G. Neuroprotective and abstinence- promoting effects of acamprosate. CNS Drugs 19: 517-537, 2005.
14. Dhaher R, Finn DA, Oberbeck DL, Yoneyama N, Snelling CC, Wu W, Hitzemann RJ. Electrolytic lesions of the medial nucleus accumbens shell selectively decrease ethanol consumption without altering preference in a limited access procedure in C57BL/6J mice. Pharmacol Biochem Behav 92: 335-42, 2009.
15. Dodd PR, Beckmann AM, Davidson MS, Wilce PA. Glutamate-mediated transmission, alcohol, and alcoholism. Neurochem Int 37: 509-533, 2000.
16. Dole VP, Gentry RT. Toward an analogue of alcoholism in mice: scale factors in the model. Proc Natl Acad Sci USA 81: 3543-3546, 1984.
17. Edgar DM, Dement WC, Fuller CA. Effects of SCN lesions on sleep and wake in squirrel monkeys: evidence for an opponent processes of sleepwake regulation. J Neurosci 13: 1065-79, 1995.
18. Ericson M, Blomqvist O, Engel JA, Söderpalm B. Voluntary ethanol intake in the rat and the associated accumbal dopamine overflow are blocked by ventral tegmental mecamylamine. Eur J Pharmacol 358: 189-196, 1998.
19. Franklin KBJ, Paxinos G. The Mouse Brain in Stereotaxic Coordinates, 3rd ed. New York: Elsevier.
20. Gessa GL, Muntoni F, Collu M, Vargiu L, Mereu G. Low doses of ethanol activate dopaminergic neurons in the ventral tegmental area. Brain Res 348: 201-203, 1985.
21. Glass JD, Grossman JH, Farnbauch L, DiNardo L. Midbrain raphe modulation of nonphotic circadian clock resetting and 5-HT release in the mammalian suprachiasmatic nucleus. J Neurosci 23: 7451-7460, 2003.
22. Glass JD, Guinn J, Kaur G, Francl JM. On the intrinsic regulation of neuropeptide Y release in the mammalian suprachiasmatic nucleus circadian clock. Eur J Neurosci 32: 1117-1126, 2010.
23. Glass JD, Lynch GR. Evidence for a brain site of melatonin action in the white-footed mouse, Peromyscus leucopus. Neuroendocrinology 34: 1-6, 1982.
24. Glass JD, Lynch GR. Melatonin: identification of sites of antigonadal action in mouse brain. Science 214: 821-823, 1981.
25. Gorwood P, Schumann G, Treutlein J, Adès J. Pharmacogenetics of alcohol-dependence. In: Gorwood P and Hamon M (eds.). Psychopharmacogenetics. Springer: New York, pp 177-201, 2006.
26. Grossman GH, Farnbauch L, Glass JD. Regulation of serotonin release in the Syrian hamster intergeniculate leaflet region. Neuroreport 15: 103-106, 2004.
27. Gupta T, Syed YM, Revis AA, Miller SA, Martinez M, Cohn KA, Demeyer MR, Patel KY, Brzezinska WJ, Rhodes JS. Acute effects of acamprosate and MPEP on ethanol drinking-in-the-dark in male C57BL/6J mice. Alcohol Clin Exp Res 32: 1992-1998, 2008.
28. Harris BR, Prendergast MA, Gibson DA, Rogers DT, Blanchard JA, Holley RC, Fu MC, Hart SR, Pedigo NW, Littleton JM. Acamprosate inhibits the binding and neurotoxic effects of trans-ACPD, suggesting a novel site of action at metabotropic glutamate receptors. Alcohol Clin Exp Res 26: 1779-1793, 2005.
29. Hartgraves MD, Fuchs JL. NMDA receptor binding in rodent suprachiasmatic nucleus. Brain Res 640: 113-118, 1994.
30. Johnson RF, Moore RY, Morin LP. Lateral geniculate lesions alter circadian activity rhythms in the hamster. Brain Res Bull 22: 411-422, 1989.
31. Kauer JA, Malenka RC. Synaptic plasticity and addiction. Nat Rev Neurosci 8: 844-858, 2007.
32. Khisti RT, Wolstenholme J, Shelton KL, Miles MF. Characterization of the ethanol-deprivation effect in substrains of C57BL/6 mice. Alcohol 40: 119-126, 2006.
33. Koob GF, Roberts AJ, Schulteis G, Parson LH, Heyser CJ, Hyytiä P, Merlo-Pich E, Weiss F. Neurocircuitry targets in ethanol reward and dependence. Alcohol Clin Exp Res 22: 3-9, 1998.
34. Kranzler HR, Gage A. Acamprosate efficacy in alcohol-dependent partients: summary of results from three pivotal trials. Am J Addict 17: 70-76, 2008.
35. Krystal JH, Petrakis IL, Mason G, Trevisan L, D'Souza DC. N-methyl- D-aspartate glutamate receptors and alcoholism: reward, dependence, treatment, and vulnerability. Pharmacol Ther 99: 79-94, 2003.
36. Larsson A, Engel JA. Neurochemical and behavioral studies on ethanol and nicotine interactions. Neurosci Biobehav Rev 27: 713-20, 2004.
37. Luo AH, Aston-Jones G. Circuit projection from suprachiasmatic nucleus to ventral tegmental area: a novel circadian output pathway. Eur J Neurosci 29: 748-760, 2009.
38. Mann K, Kiefer F, Spanagel R, Littleton J. Acamprosate: recent findings and future research directions. Alcohol Clin Exp Res 32: 1105-1110, 2008.
39. Melendez RI, Middaugh LD, Kalivas PW. Development of an alcohol deprivation and escalation effect in C57BL/6J mice. Alcohol Clin Exp Res 30: 2017-2025, 2006.
40. Moore RY. Organization and function of a central nervous system oscillator: the suprachiasmatic hypothalamic nucleus. Fed Proc 42: 2783-2789, 1983.
41. Moore RY, Speh JC. GABA is the principal neurotransmitter of the circadian system. Neurosci Lett 150: 112-116, 1993.
42. Naassila M, Hammoumi S, Legrand E, Durbin P, Daoust M. Mechanism of action of acamprosate. Part I. Characterization of spermidinesensitive acamprosate binding site in rat brain. Alcohol Clin Exp Res 22: 802-809, 1998.
43. Nie H, Rewal M, Gill TM, Ron D, Janak PH. Extrasynaptic -containing GABAA receptors in the nucleus accumbens dorsomedial shell contribute to alcohol intake. Proc Natl Acad Sci USA 108: 4459-64, 2011.
44. Olive MF, Nannini MA, Ou CJ, Koenig HN, Hodge CW. Effects of acute acamprosate and homotaurine on ethanol intake and ethanol-stimulated mesolimbic dopamine release. Eur J Pharmacol 437: 55-61, 2002.
45. Prosser RA, Mangrum CA, Glass JD. Acute ethanol modulates glutamatergic and serotonergic phase shifts of the mouse circadian clock in vitro. Neuroscience 152: 837-848, 2008.
46. Renoldi G, Calcagno E, Borsini F, Invernizzi RW. Stimulation of group I mGlu receptors in the ventrotegmental area enhances extracellular dopamine in the rat medial prefrontal cortex. J Neurochem 100: 1658-1666, 2007.
47. Rosenwasser AM. Circadian clock genes: non-circadian roles in sleep, addiction, and psychiatric disorders? Neurosci Biobehav Rev 38: 1249-1255, 2010.
48. Rösner S, Hackl-Herrwerth A, Leucht S, Lehert P, Vecchi S, Soyka M. Acamprosate for alcohol dependence. Cochrane Database Syst Rev 8: CD004332, 2010.
49. Ruby CL, Brager AJ, DePaul MA, Prosser RA, Glass JD. Chronic ethanol disrupts circadian behavior and photic phase-resetting in the hamster. Am J Physiol Regul Integr Comp Physiol 297: R729-R737, 2009.
50. Ruby CL, Prosser RA, DePaul MA, Roberts RJ, Glass JD. Acute ethanol impairs photic and nonphotic circadian phase resetting in the Syrian hamster. Am J Physiol Regul Integr Comp Physiol 296: R411-R418, 2009.
51. Ryabinin AE, Galvan-Rosas A, Bachtell RK, Risinger FO. High alcohol/sucrose consumption during dark circadian phase in C57BL/6J mice: involvement of hippocampus, lateral spetum and urocortin-positive cells of the Edinger-Westphal nucleus. Psychopharmacology 165: 296-305, 2003.
52. Samson HH, Chappell A. Injected muscimol in pedunculopontine tegmental nucleus alters ethanol self-administration. Alcohol 23: 41-8, 2001.
53. Spanagel R, Kiefer F. Drugs for relapse prevention of alcoholism: ten years of progress. Trends Pharmacol Sci 29: 109-115, 2008.
54. Spanagel R, Hölter SM. Long-term alcohol self-administration with repeated alcohol deprivation phases: an animal model of alcoholism? Alcohol Alcohol 34: 231-243, 1999.
55. Spanagel R, Hölter SM, Allingham K, Landgraf R, Zieglgänsberger W. Acamprosate and alcohol: I. effects on alcohol intake following alcohol deprivation in the rat. Eur J Pharmacol 305: 39-44, 1996.
56. Spanagel R, Pendyala G, Abarca C, Zghoul T, Sanchis-Segura C, Magnone MC, Lascorz J, Depner M, Holzberg D, Soyka M, Schreiber S, Matsuda F, Lathrop M, Schumann G, Albrecht U. The clock gene mPer2 influences the glutamatergic system and modulates alcohol consumption. Nat Med 11: 35-42, 2005.
57. Spanagel R, Weiss F. The dopamine hypothesis of reward: past and current status. Trends Neurosci 22: 521-527, 1999.
58. Stamp JA, Piggins HD, Rusak B, Semba K. Distribution of ionotropic glutamate receptor subunit immunoreactivity in the suprachiasmatic nucleus and intergeniculate leaflet of the hamster. Brain Res 756: 215-224, 1997.
59. Stromberg MF, Mackler SA, Volpicelli JR, O'Brien CP. Effect of acamprosate and naltrexone, alone or in combination, on ethanol consumption. Alcohol 23: 109-116, 2001.
60. Vengeliene V, Celerier E, Chaskiel L, Penzo F, Spanagel R. Compulsive alcohol drinking in rodents. Addict Biol 14: 384-396, 2009.
61. Vrang N, Mrosovsky N, Mikkelsen JD. Afferent projections to the hamster intergeniculate leaflet demonstrated by retrograde and anterograde tracing. Brain Res Bull 59: 267-288, 2003.
62. Wasielewski JA, Holloway FA. Alcohol's interactions with circadian rhythms. Alcohol Res Health 25: 94-100, 2001.
63. Webb IC, Baltazar RM, Wang X, Pitchers KK, Coolen LM, Lehman MN. Diurnal variations in natural and drug reward, mesolimbic tyrosine hydroxylase, and clock gene expression in the male rat. J Biol Rhythms 24: 465-76, 2009.
64. Wilde MI, Wagstaff Acamprosate AJ. A review of its pharmacology and clinical potential in the management of alcohol dependence after detoxification. Drugs 53: 1038-1053, 1997.
65. Zhao Y, Dayas CV, Aujla H, Baptista MA, Martin-Fardon R, Weiss F. Activation of group II metabotropic glutamate receptors attenuates both stress and cue-induced ethanol-seeking and modulates c-fos expression in the hippocampus and amygdale. J Neurosci 26: 9967-74, 2006.
66. Zornoza T, Cano M, Polache A, Granero L. Pharmacology of acamprosate: an overview. CNS Drug Rev 9: 359-374, 2003.