Growth inhibitory, apoptotic and anti-inflammatory activities displayed by a novel modified triterpenoid, cyano enone of methyl boswellates

Journal of Biosciences

Volumn 36, Issue 2, 2011, Pages 297-307

  Ravanan, Palaniyandi ^a,b   Singh, Sanjay K ^a   Rao, G S R Subba ^a   Kondaiah, Paturu ^a  

^a INDIAN INSTITUTE OF SCIENCE   (India)

^b VIT UNIVERSITY   (India)

Author keywords

Cancer therapeutics; cytotoxicity; differentiation; natural products

Indexed keywords

BOSWELLIC ACID; CASPASE 3; CASPASE 8; DNA; NITRIC OXIDE; TRITERPENOID; ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT; GROWTH INHIBITOR; TRITERPENE;

CANCER; CONCENTRATION (COMPOSITION); DNA; GROWTH; INHIBITION; ORGANIC COMPOUND; SECONDARY METABOLITE; TOXICITY; TUMOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL DIFFERENTIATION; CHEMICAL MODIFICATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA FRAGMENTATION; DNA SYNTHESIS INHIBITION; DRUG CYTOTOXICITY; DRUG STRUCTURE; ENZYME ACTIVATION; FEMALE; GLIOMA; GROWTH INHIBITION; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; MOUSE; NONHUMAN; TUMOR VOLUME; TUMOR XENOGRAFT; ANIMAL; C57BL MOUSE; CELL LINE; DNA REPLICATION; DRUG EFFECT; DRUG SCREENING; IC 50; MACROPHAGE; METABOLISM; NUDE MOUSE; RAT;

MUS;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 3; CASPASE 8; CELL DIFFERENTIATION; CELL LINE; DNA FRAGMENTATION; DNA REPLICATION; ENZYME ACTIVATION; FEMALE; GROWTH INHIBITORS; HUMANS; INHIBITORY CONCENTRATION 50; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, NUDE; NITRIC OXIDE; RATS; TRITERPENES; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 80053621759     PISSN: 02505991     EISSN: 09737138     Source Type: Journal    
DOI: 10.1007/s12038-011-9056-7     Document Type: Article

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