Measurements of elastic moduli of silicone gel substrates with a microfluidic device

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Gutierrez, Edgar ^a   Groisman, Alex ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POLYACRYLAMIDE; SILICONE GEL; BAYSILON; DIMETICONE; GLASS;

ARTICLE; CELL ADHESION; CONTROLLED STUDY; FLUORESCENCE ANALYSIS; FLUORESCENCE MICROSCOPE; MATERIAL COATING; MATHEMATICAL MODEL; MICROFLUIDICS; MICROSCOPY; REPRODUCIBILITY; RIGIDITY; SHEAR STRESS; TENSILE STRENGTH; THICKNESS; TRACTION FORCE MICROSCOPY; YOUNG MODULUS; CHEMISTRY; LIGHT RELATED PHENOMENA; MECHANICAL STRESS; METHODOLOGY; MICROFLUIDIC ANALYSIS; TIME;

ANIMALIA;

DIMETHYLPOLYSILOXANES; ELASTIC MODULUS; GLASS; MICROFLUIDIC ANALYTICAL TECHNIQUES; OPTICAL PROCESSES; SILICONE GELS; STRESS, MECHANICAL; TIME FACTORS;

EID: 80053611076     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025534     Document Type: Article

References (48)

1. Nemir S, West JL, (2009) Synthetic materials in the study of cell response to substrate rigidity. Ann Biomed Eng 38: 2-20.
2. Isenberg BC, Dimilla PA, Walker M, Kim S, Wong JY, (2009) Vascular smooth muscle cell durotaxis depends on substrate stiffness gradient strength. Biophys J 97: 1313-1322.
3. Dubin-Thaler BJ, Hofman JM, Cai Y, Xenias H, Spielman I, et al. (2008) Quantification of cell edge velocities and traction forces reveals distinct motility modules during cell spreading. PLoS One 3: e3735.
4. Ingber DE, Folkman J, (1989) Mechanochemical switching between growth and differentiation during fibroblast growth factor-stimulated angiogenesis in vitro: role of extracellular matrix. J Cell Biol 109: 317-330.
5. Reilly GC, Engler AJ, (2010) Intrinsic extracellular matrix properties regulate stem cell differentiation. J Biomech 43: 55-62.
6. Engler AJ, Sen S, Sweeney HL, Discher DE, (2006) Matrix elasticity directs stem cell lineage specification. Cell 126: 677-689.
7. Zaman MH, Trapani LM, Sieminski AL, Mackellar D, Gong H, et al. (2006) Migration of tumor cells in 3D matrices is governed by matrix stiffness along with cell-matrix adhesion and proteolysis. Proc Natl Acad Sci U S A 103: 10889-10894.
8. Krndija D, Schmid H, Eismann JL, Lother U, Adler G, et al. (2010) Substrate stiffness and the receptor-type tyrosine-protein phosphatase alpha regulate spreading of colon cancer cells through cytoskeletal contractility. Oncogene 29: 2724-2738.
9. Munevar S, Wang YL, Dembo M, (2001) Traction force microscopy of migrating normal and H-ras transformed 3T3 fibroblasts. Biophysical Journal 80: 1744-1757.
10. Pelham RJ, Wang YL, (1997) Cell locomotion and focal adhesions are regulated by substrate flexibility. Proceedings Of The National Academy Of Sciences Of The United States Of America 94: 13661-13665.
11. Harris AK, Stopak D, Wild P, (1981) Fibroblast Traction As A Mechanism For Collagen Morphogenesis. Nature 290: 249-251.
12. Burton K, Taylor DL, (1997) Traction forces of cytokinesis measured with optically modified elastic substrata. Nature 385: 450-454.
13. Balaban NQ, Schwarz US, Riveline D, Goichberg P, Tzur G, et al. (2001) Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates. Nat Cell Biol 3: 466-472.
14. Schwarz US, Balaban NQ, Riveline D, Bershadsky A, Geiger B, et al. (2002) Calculation of forces at focal adhesions from elastic substrate data: The effect of localized force and the need for regularization. Biophysical Journal 83: 1380-1394.
15. Cesa CM, Kirchgessner N, Mayer D, Schwarz US, Hoffmann B, et al. (2007) Micropatterned silicone elastomer substrates for high resolution analysis of cellular force patterns. Review Of Scientific Instruments 78.
16. Iwadate Y, Yumura S, (2008) Molecular dynamics and forces of a motile cell simultaneously visualized by TIRF and force microscopies. Biotechniques 44: 739-+.
17. Frey MT, Engler A, Discher DE, Lee J, Wang YL, (2007) Microscopic methods for measuring the elasticity of gel substrates for cell culture: Microspheres, microindenters, and atomic force microscopy. Cell Mechanics pp. 47-65.
18. Schneider F, Fellner T, Wilde J, Wallrabe U, (2008) Mechanical properties of silicones for MEMS. Journal Of Micromechanics And Microengineering 18.
19. Dimitriadis EK, Horkay F, Maresca J, Kachar B, Chadwick RS, (2002) Determination of elastic moduli of thin layers of soft material using the atomic force microscope. Biophysical Journal 82: 2798-2810.
20. Bot A, vanAmerongen IA, Groot RD, Hoekstra NL, Agterof WGM, (1996) Large deformation rheology of gelatin gels. Polymer Gels And Networks 4: 189-227.
21. Reinhart-King CA, Dembo M, Hammer DA, (2003) Endothelial cell traction forces on RGD-derivatized polyacrylamide substrata. Langmuir 19: 1573-1579.
22. Jacot JG, Dianis S, Schnall J, Wong JY, (2006) A simple microindentation technique for mapping the microscale compliance of soft hydrated materials and tissues. Journal Of Biomedical Materials Research Part A 79A: 485-494.
23. Boudou T, Ohayon J, Arntz Y, Finet G, Picart C, et al. (2006) An extended modeling of the micropipette aspiration experiment for the characterization of the Young's modulus and Poisson's ratio of adherent thin biological samples: Numerical and experimental studies. Journal Of Biomechanics 39: 1677-1685.
24. Gunning AP, Kirby AR, Ridout MJ, Brownsey GJ, Morris VJ, (1996) Investigation of gellan networks and gels by atomic force microscopy. Macromolecules 29: 6791-6796.
25. Domke J, Radmacher M, (1998) Measuring the elastic properties of thin polymer films with the atomic force microscope. Langmuir 14: 3320-3325.
26. Mahaffy RE, Shih CK, MacKintosh FC, Kas J, (2000) Scanning probe-based frequency-dependent microrheology of polymer gels and biological cells. Physical Review Letters 85: 880-883.
27. Uricanu VI, Duits MHG, Nelissen RMF, Bennink ML, Mellema J, (2003) Local structure and elasticity of soft gelatin gels studied with atomic force microscopy. Langmuir 19: 8182-8194.
28. Tse JR, Engler AJ, (2010) Preparation of hydrogel substrates with tunable mechanical properties. Current protocols in cell biology 10: 10.16.11-10.16.16.
29. Peyton SR, Putnam AJ, (2005) Extracellular matrix rigidity governs smooth muscle cell motility in a biphasic fashion. Journal Of Cellular Physiology 204: 198-209.
30. Kizilay MY, Okay O, (2003) Effect of initial monomer concentration on spatial inhomogeneity in poly(acrylamide) gels. Macromolecules 36: 6856-6862.
31. Gutierrez E, Petrich BG, Shattil SJ, Ginsberg MH, Groisman A, et al. (2008) Microfluidic devices for studies of shear-dependent platelet adhesion. Lab On A Chip 8: 1486-1495.
32. Groisman A, Enzelberger M, Quake SR, (2003) Microfluidic memory and control devices. Science 300: 955-958.
33. Boudou T, Ohayon J, Picart C, Tracqui P, (2006) An extended relationship for the characterization of Young's modulus and Poisson's ratio of tunable polyacrylamide gels. Biorheology 43: 721-728.
34. Mark JE, (1999) Polymer Data Handbook Oxford Oxford University Press.
35. Ji L, Danuser G, (2005) Tracking quasi-stationary flow of weak fluorescent signals by adaptive multi-frame correlation. Journal Of Microscopy-Oxford 220: 150-167.
36. Campbell K, Fainman Y, Groisman A, (2007) Pneumatically actuated adaptive lenses with millisecond response time. Applied Physics Letters 91.
37. Blatz PJ, Sharda SC, Tschoegl NW, (1974) Strain Energy Function For Rubber-Like Materials Based On A Generalized Measure Of Strain. Transactions Of The Society Of Rheology 18: 145-161.
38. Fray TR, Molloy JE, Armitage MP, Sparrow JC, (1998) Quantification of single human dermal fibroblast contraction. Tissue Engineering 4: 281-291.
39. Feral CC, Zijlstra A, Tkachenko E, Prager G, Gardel ML, et al. (2007) CD98hc (SLC3A2) participates in fibronectin matrix assembly by mediating integrin signaling. Journal Of Cell Biology 178: 701-711.
40. Gutierrez E, Tkachenko E, Besser A, Sundd P, Ley K, et al. (2011) High Refractive Index Silicone Gels as Substrates with Physiological Rigidity for Simultaneous Total Internal Reflection Fluorescence and Traction Force Microscopy of Adherent Cells. Accepted to PLoS One.
41. Wang N, Naruse K, Stamenovic D, Fredberg JJ, Mijailovich SM, et al. (2001) Mechanical behavior in living cells consistent with the tensegrity model. Proceedings Of The National Academy Of Sciences Of The United States Of America 98: 7765-7770.
42. Stricker J, Sabass B, Schwarz US, Gardel ML, (2010) Optimization of traction force microscopy for micron-sized focal adhesions. Journal Of Physics-Condensed Matter 22.
43. Richert L, Engler AJ, Discher DE, Picart C, (2004) Elasticity of native and cross-linked polyelectrolyte multilayer films. Biomacromolecules 5: 1908-1916.
44. Tkachenko E, Gutierrez E, Ginsberg MH, Groisman A, (2009) An easy to assemble microfluidic perfusion device with a magnetic clamp. Lab On A Chip 9: 1085-1095.
45. Bang H, Lee WG, Park J, Yun H, Lee J, et al. (2006) Active sealing for soft polymer microchips: method and practical applications. Journal Of Micromechanics And Microengineering 16: 708-714.
46. Schmid H, Michel B, (2000) Siloxane polymers for high-resolution, high-accuracy soft lithography. Macromolecules 33: 3042-3049.
47. Gambin Y, VanDelinder V, Ferreon ACM, Lemke EA, Groisman A, et al. (2011) Visualizing a one-way protein encounter complex by ultrafast single-molecule mixing. Nature Methods 8: 239-243.
48. Iwadate Y, Yumura S, (2008) Actin-based propulsive forces and myosin-II-based contractile forces in migrating Dictyostelium cells. Journal Of Cell Science 121: 1314-1324.