[125I][Tyr3]octreotide labels human somatostatin sst2 and sst5 receptors

European Journal of Pharmacology

Volumn 348, Issue 2-3, 1998, Pages 311-320

  Siehler, Sandra ^a   Seuwen, K ^a   Hoyer, D ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

CCL39 Chinese hamster lung fibroblast cells; Octreotide; Somatostatin (SRIF); Somatostatin sst2 receptor, recombinant; Somatostatin sst5 receptor, recombinant(i)

Indexed keywords

ANGIOPEPTIN; BIM 23030; CGP 23996; CORTISTATIN 14; DEXTRO PHENYLALANYLPHENYLALANYLPHENYLALANYL DEXTRO TRYPTOPHYLLYSYLTHREONYLPHENYLALANYLTHREONINAMIDE; DEXTRO PHENYLALANYLPHENYLALANYLTYROSYL DEXTRO TRYPTOPHYLLYSYLVALYLPHENYLALANYL DEXTRO [3 (2 NAPHTHYL)ALANINAMIDE]; IODINE 125; L 361301; L 362855; OCTREOTIDE; OCTREOTIDE[3 TYROSINE]; RADIOLIGAND; SEGLITIDE; SOMATOSTATIN DERIVATIVE; SOMATOSTATIN RECEPTOR; UNCLASSIFIED DRUG; VAPREOTIDE; CYCLOPEPTIDE; DRUG DERIVATIVE; OCTREOTIDE, IODOTYR(3); OCTREOTIDE, IODOTYR(3)-; RADIOACTIVE IODINE; SOMATOSTATIN; SOMATOSTATIN RECEPTOR 2; SOMATOSTATIN RECEPTOR 5;

ANIMAL CELL; ARTICLE; CHINESE HAMSTER; CONTROLLED STUDY; DRUG RECEPTOR BINDING; HORMONE RELEASE; LIGAND BINDING; LUNG FIBROBLAST; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; TUMOR GROWTH; ANIMAL; BINDING COMPETITION; CELL LINE; CRICETULUS; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; HAMSTER; HUMAN; METABOLISM; RADIOASSAY; STRUCTURE ACTIVITY RELATION;

ANIMALS; BINDING, COMPETITIVE; CELL LINE; CRICETINAE; CRICETULUS; HUMANS; IODINE RADIOISOTOPES; OCTREOTIDE; PEPTIDES, CYCLIC; RADIOLIGAND ASSAY; RECEPTORS, SOMATOSTATIN; SOMATOSTATIN; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 0032495867     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(98)00159-9     Document Type: Article

References (70)

1. Bauer W., Briner U., Doepfner W., Haller R., Huguenin R., Marbach P., Petcher T.J., Pless J. SMS 201-995: a very potent and selective octapeptide analogue of somatostatin with prolonged action. Life Sci. 31:1982;1133-1140.
2. Bell G.I., Reisine T. Molecular biology of somatostatin receptors. Trends Neurosci. 16:1993;34-38.
3. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
4. Breder C.D., Yamada Y., Yasuda K., Seino S., Saper C.B., Bell G.I. Differential expression of somatostatin receptor subtypes in brain. J. Neurosci. 12:1992;3920-3934.
5. Bruno J.F., Xu Y., Song J., Berelowitz M. Molecular cloning and functional expression of a brain-specific somatostatin receptor. Proc. Natl. Acad. Sci. USA. 89:1992;11151-11155.
6. Bruns C., Weckbecker G., Raulf F., Kaupmann K., Hoyer D., Lübbert H. Molecular pharmacology of somatostatin receptor subtypes. Ann. New York Acad. Sci. 733:1994;138-146.
7. Bruns, C., Weckbecker, G., Raulf, F., Kaupmann, K., Schoeffter, P., Lübbert, H., Hoyer, D., 1995. Characterization of somatostatin receptor subtypes. in: Somatostatin and Its Receptors (CIBA Foundation Meeting 190), Wiley, Chichester, pp. 89-100.
8. 2 may mediate the antiproliferative effect of octreotide. Gastroenterology. 104:1993;816-819.
9. 5 through different mechanisms. Proc. Natl. Acad. Sci. USA. 92:1994;1580-1584.
10. 1 cell cycle block. Endocrinology. 136:1995;4174-4181.
11. Czernik A.J., Petrack B. Somatostatin receptor binding in rat cerebral cortex. J. Biol. Chem. 258:1983;5525-5530.
12. De Lean, 1979. SCTFIT: A Computer Program for Simultaneous Analysis of Saturation and Competition Curves, Howard Hughes Medical Institute, Duke University Medical Center, Durham, NC.
13. De Lecea L., Criado J.R., Prospero-Garcia O., Gautvik K.M., Schweitzer P., Danielson P.E., Dunlop C.L., Siggins G.R., Henriksen S.J., Sutcliffe J.G. A cortical neuropeptide with neuronal depressant and sleep-modulating properties. Nature. 381:1996;242-245.
14. De Lecea L., Del Rio J.A., Criado J.R., Alcantara S., Morales M., Danielson P.E., Henriksen S.J., Soriano E., Sutcliffe J.G. Cortistatin is expressed in a distinct subset of cortical interneurons. J. Neurosci. 17:1997;5868-5880.
15. 125I ]CGP 23996 binding sites in the rat brain: comparison with membrane binding Peptides. 6:1985;713-719.
16. Finley J.C., Maderdrut J.L., Roger L.J., Pertrusz P. The immunocytochemical localization of somatostatin-containing neurons in the rat central nervous system. Neuroscience. 6:1981;2173-2192.
17. Fukusumi S., Kitada C., Takekawa S., Kizawa H., Sakamoto J., Miyamato M., Hinuma S., Kitano K., Fujino M. Identification and characterization of a novel human cortistatin-like peptide. Biochem. Biophys. Res. Commun. 232:1997;157-163.
18. Hebert T.E., Moffett S., Morello J.-P., Loisel T.P., Bichet D.G., Barret C., Bouvier M. A peptide derived from a b2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation. J. Biol. Chem. 271:1996;16384-16392.
19. Hjorth S.A., Thirstrup K., Schwartz T.W. Radioligand-dependent discrepancy in agonist affinities enhanced by mutations in the k-opioid receptor. Mol. Pharmacol. 50:1996;977-984.
20. Hoyer D., Lübbert H., Bruns C. Molecular pharmacology of somatostatin receptors. Naunyn Schmiedeberg's Arch. Pharmacol. 350:1994;441-453.
21. Hoyer D., Bell G.I., Berelowitz M., Epelbaum J., Feniuk W., Humphrey P.P.A., O'Carroll A.M., Patel Y.C., Schonbrunn A., Taylor J.E., Reisine T. Classification and nomenclature of somatostatin receptors. Trends Pharmacol. Sci. 16:1995;86-88.
22. 1 receptors. Eur. J. Pharmacol. 289:1995;151-161.
23. Kaupmann K., Bruns C., Hoyer D., Seuwen K., Lübbert H. Distribution and second messenger coupling of four somatostatin receptor subtypes expressed in brain. FEBS Lett. 331:1993;53-59.
24. Kluxen F.W., Bruns C., Luebbert H. Expression cloning of a rat brain somatostatin receptor cDNA. Proc. Natl. Acad. Sci. USA. 89:1992;4618-4622.
25. 111In -DPTA-D-Phe1]octreotide Ann. N.Y. Acad. Sci. 733:1994;496-506.
26. Kubota A., Yamada Y., Kagimoto S.et al. Identification of somatostatin receptor subtypes and an implication for the efficacy of somatostatin analogue SMS 201-955 in treatment of human endocrine tumours. J. Clin. Invest. 93:1994;1321-1325.
27. Lamberts S.W., Koper J.W., Reubi J.C. Potential role of somatostatin analogues in the treatment of cancer. Eur. J. Clin. Invest. 17:1987;281-287.
28. Lamberts S.W., Krenning E.P., Reubi J.C. The role of somatostatin and its analogues in the diagnosis and treatment of tumours. Endocrine Rev. 12:1991;450-482.
29. Lefkowitz R.J., Cotecchia S., Samana P., Costa T. Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins. Trends Pharmacol. Sci. 14:1993;303-307.
30. Li X.J., Forte M., North R.A., Ross C.A., Snyder S.H. Cloning and expression of a rat somatostatin receptor enriched in brain. J. Biol. Chem. 267:1992;21307-21312.
31. Martin J.L., Chesselet M.F., Raynor K., Gonzales C., Reisine T. Differential distribution of somatostatin receptor subtypes in rat brain revealed by newly developed somatostatin analogues. Neuroscience. 41:1991;581-593.
32. Meyerhof W., Wulfsen I., Schoenrock C., Fehr S., Richter D. Molecular cloning of a somatostatin-28 receptor and comparison of its expression pattern with that of a somatostatin-14 receptor in rat brain. Proc. Natl. Acad. Sci. USA. 89:1992;10267-10271.
33. O'Carroll A.M., Lolait S.J., Koenig M., Mahan L.C. Molecular cloning and expression of a pituitary somatostatin receptor with preferential affinity for somatostatin-28. Mol. Pharmacol. 42:1992;939-946.
34. 5. Mol. Pharmacol. 63:1994;127-133.
35. 1-5). Endocrinology. 135:1994;2814-2817.
36. Patel, Y.C., Zingg, H.H., Srikant, C.B., 1985. Somatostatin-14-like immunoreactive forms in the rat: characterization, distribution and biosynthesis. In: Patel, Y.C., Tannenbaum, G.S. (Eds.), Advances in Experimental Biology and Medicine, Vol. 188: Somatostatin, New York, pp. 71-87.
37. 1-5) are functionally coupled to adenylyl cyclase. Biochem. Biophys. Res. Commun. 198:1994;605-612.
38. Patel Y.C., Greenwood M.T., Panetta R., Demchyshyn L., Niznik H., Srikant C.B. The somatostatin receptor family. Life Sci. 57:1995;1249-1265.
39. Piwko C., Thoss V.S., Probst A., Hoyer D. Somatostatin receptors in the human brain: radioligand binding. Naunyn Schmiedeberg's Arch. Pharmacol. 355:1997;161-167.
40. 1-5, in the CNS and peripheral tissue. Digestion. 55:1994;46-53.
41. Raynor K., Reisine T. Analogues of somatostatin selectively label distinct subtypes of somatostatin receptors in rat brain. J. Pharmacol. Exp. Ther. 251:1989;510-517.
42. Raynor K., Reisine T. Differential coupling of somatostatin-1 receptors to adenylyl cyclase in the rat striatum vs. the pituitary and other regions of the rat brain. J. Pharmacol. Exp. Ther. 260:1992;841-848.
43. Raynor K., Coy D.C., Reisine T. Analogues of somatostatin bind selectively to brain somatostatin receptor subtypes. J. Neurochem. 59:1992;1241-1250.
44. Raynor K., Murphy W.A., Coy D.H., Taylor J.E., Moreau J.-P., Yasuda K., Bell G.I., Reisine T. Cloned somatostatin receptors: identification of subtype-selective peptides and demonstration of high affinity binding of linear peptides. Mol. Pharmacol. 43:1993;838-844.
45. 5. Mol. Pharmacol. 44:1993;385-392.
46. Reichlin, S., 1983. Somatostatin. N. Engl. J. Med. 309, 1495-1505, 1556-1563.
47. Reisine, T., Woulfe, D., Raynor, K. et al., 1995. Interaction of somatostatin receptors with G-proteins and cellular effector systems. In: Somatostatin and Its Receptors. Wiley, Chichester (Ciba Found. Symp. 190) pp. 160-170.
48. Reubi J.C. Evidence for two somatostatin-14 receptor types in rat brain cortex. Neurosci. Lett. 49:1984;259-263.
49. Reubi J.C. New specific radioligand for one subpopulation of brain somatostatin receptors. Life Sci. 36:1985;1829-1836.
50. Reubi J.C., Landolt A.M. High density of somatostatin receptors in pituitary tumours from acromegalic patients. J. Clin. Endocrinol. Metab. 59:1984;1148-1153.
51. Reubi J.C., Maurer R. Different ionic requirements for somatostatin receptor subpopulations in the brain. Regul. Pept. 14:1986;301-311.
52. Reubi J.C., Lang W., Maurer R., Koper J.W., Lamberts S.W.J. Distribution and biochemical characterization of somatostatin receptors in tumours of the human central nervous system. Cancer Res. 47:1987;5758-5765.
53. Reubi J.C., Kvols L., Krenning E.P., Lamberts S.W.J. Distribution of somatostatin receptors in normal and tumour tissue. Metabolism. 39:1990;78-81.
54. Reubi J.C., Kvols L., Waser B.et al. Detection of somatostatin receptors in surgical and percutaneous needle biopsy samples of carcinoids and islets cell carcinomas. Cancer Res. 50:1990;5969-5977.
55. Robbins R.J., Reichlin S. Somatostatin biosynthesis by cerebral cortical cells in monolayer culture. Endocrinology. 113:1983;574-581.
56. Rohrer L., Raulf F., Bruns C., Buettner R., Hofstaedter F., Schuele R. Cloning and characterization of a fourth somatostatin receptor. Proc. Natl. Acad. Sci. USA. 90:1993;4196-4200.
57. Romano C., Yang W.-L., O'Malley K.L. Metabotropic glutamate receptor 5 is a disulfide-linked dimer. J. Biol. Chem. 271:1996;28612-28616.
58. Schally A.V. Oncological applications of somatostatin analogues. Cancer Res. 48:1988;6977-6985.
59. Schloos J., Raulf F., Hoyer D., Bruns C. Identification and characterization of somatostatin receptors in rat lung. Br. J. Pharmacol. 121:1997;963-971.
60. 2 receptors. Eur. J. Pharmacol. 289:1995;163-173.
61. Schwartz T.W., Rosenkilde M.M. Is there a 'lock for all agonist' keys in 7TM receptors? Trends Pharmacol. Sci. 17:1996;213-216.
62. Srikant C.B. Cell cycle dependent induction of apoptosis by somatostatin analog SMS 201-995 in AtT-20 mouse pituitary cells. Biochem. Biophys. Res. Commun. 209:1995;400-406.
63. 3H ]ketanserin labeling of 5-hydrotxytryptamine-2-(5-HT2) receptors in mammalian cells transfected with a rat 5-HT2 cDNA: evidence for multiple states and not multiple 5-HT2 receptor subtypes Mol. Pharmacol. 38:1990;594-598.
64. 2b). FEBS Lett. 311:1992;290-294.
65. Walker M.W., Smith K.E., Bard J., Vaysse P.J.-J., Gerald C., Daouti S., Weinshank R.L., Branchek T.A. A structure-activity analysis of the cloned rat and human Y4 receptors for pancreatic polypeptide. Trends Pharmacol. Sci. 18:1997;609-612.
66. 5) human somatostatin receptor subtype. Biochem. Biophys. Res. Commun. 195:1993;844-852.
67. Yamada Y., Post S.R., Wang K., Tager H.S., Bell G.I., Seino S. Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney. Proc. Natl. Acad. Sci. USA. 89:1992;251-255.
68. 3, a protein coupled to adenylyl cyclase. Mol. Endocrinol. 6:1992;2136-2142.
69. 3, coupled to adenylylcyclase. J. Biol. Chem. 267:1992;20422-20428.
70. Zingg H.H., Patel Y.C. Biosynthesis of immunoreactive somatostatin by hypothalamic neurons in culture. J. Clin. Invest. 70:1982;1101-1109.