Thermosensitization and induction of apoptosis or cell-cycle arrest via the MAPK cascade by parthenolide, an NF-κB inhibitor, in human prostate cancer androgen-independent cell lines

International Journal of Molecular Medicine

Volumn 28, Issue 6, 2011, Pages 1033-1042

  Hayashi, Sachiko ^a   Koshiba, Ken ^b   Hatashita, Masanori ^c   Sato, Takefumi ^d   Jujo, Yutaka ^b   Suzuki, Ryuta ^b   Tanaka, Yukie ^a   Shioura, Hiroki ^a  

^a UNIVERSITY OF FUKUI   (Japan)

^b Saitama Ken oh Hospital   (Japan)

^c WAKASA WAN ENERGY RESEARCH CENTER   (Japan)

^d KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Apoptosis; Cell cycle arrest; DU145 cells; ERK1 2; Hyperthermia; MAPK cascade; NF B inhibitor; p38; Parthenolide; PC3 cells; SAPK JNK; Step up heating; Thermosensitization

Indexed keywords

ANDROGEN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PARTHENOLIDE; STRESS ACTIVATED PROTEIN KINASE;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CONTROLLED STUDY; FLOW CYTOMETRY; HEAT SENSITIVITY; HEAT TOLERANCE; HEATING; HUMAN; HUMAN CELL; HYPERTHERMIA; PRIORITY JOURNAL; PROSTATE CANCER;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CELL DIVISION; CELL LINE, TUMOR; COMBINED MODALITY THERAPY; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLOW CYTOMETRY; G2 PHASE CELL CYCLE CHECKPOINTS; HOT TEMPERATURE; HUMANS; HYPERTHERMIA, INDUCED; MALE; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NF-KAPPA B; PROSTATIC NEOPLASMS; SESQUITERPENES;

EID: 80053514160     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2011.760     Document Type: Article

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