Thermosensitization by parthenolide in human lung adenocarcinoma A549 cells and p53- and hsp72-independent apoptosis induction via the nuclear factor-κB signal pathway

International Journal of Molecular Medicine

Volumn 21, Issue 5, 2008, Pages 585-592

  Hayashi, Sachiko ^a   Hatashita, Masanori ^b   Hayashi, Akio ^c   Matsumoto, Hideki ^a   Shioura, Hiroki ^a   Kitai, Ryuhei ^a  

^a UNIVERSITY OF FUKUI   (Japan)

^b Department of Research and Development ^*  (Japan)

^c OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

A549 cells; Apoptosis; Hsp72; Hyperthermia; Necrosis; Nuclear factor B; p53; Parthenolide; Thermosensitivity

Indexed keywords

HEAT SHOCK PROTEIN 72; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PARTHENOLIDE; PROTEIN P53; ANTINEOPLASTIC AGENT; SESQUITERPENE;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL DEATH; CELL KINETICS; CELL STRESS; CELL TRANSFORMATION; CONTROLLED STUDY; DRUG EXPOSURE; HUMAN; HUMAN CELL; HYPERTHERMIA; HYPERTHERMIC THERAPY; IN VITRO STUDY; INCIDENCE; INCUBATION TIME; LUNG ADENOCARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TEMPERATURE SENSITIVITY; ANIMAL; DRUG EFFECT; GENETICS; HEAT; LUNG TUMOR; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; HEAT; HSP72 HEAT-SHOCK PROTEINS; HUMANS; LUNG NEOPLASMS; NF-KAPPA B; SESQUITERPENES; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 46449130417     PISSN: 11073756     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijmm.21.5.585     Document Type: Article

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