IL-7 is required for the development of the intrinsic function of marginal zone B cells and the marginal zone microenvironment

Journal of Immunology

Volumn 187, Issue 7, 2011, Pages 3587-3594

  Willems, Leen ^a,b   Li, Shengqiao ^a   Rutgeerts, Omer ^a   Lenaerts, Caroline ^a   Waer, Mark ^a   Billiau, An D ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN M; IMMUNOGLOBULIN M ANTIBODY; INTERLEUKIN 7;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY PRODUCTION; ARTICLE; B LYMPHOCYTE; CELL STRUCTURE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; GRAFT REJECTION; HAMSTER; HEART TRANSPLANTATION; MARGINAL ZONE B LYMPHOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SCID MOUSE; T LYMPHOCYTE; WILD TYPE; XENOGRAFT;

ANIMALS; B-LYMPHOCYTES; CELL SEPARATION; CRICETINAE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HEART TRANSPLANTATION; IMMUNOGLOBULIN M; INTERLEUKIN-7; LYMPHOCYTE CULTURE TEST, MIXED; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; SPLEEN; TRANSPLANTATION, HETEROLOGOUS;

EID: 80053483958     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1004012     Document Type: Article

References (33)

1. Vos, Q., A. Lees, Z. Q. Wu, C. M. Snapper, and J. J. Mond. 2000. B-cell activation by T-cell-independent type 2 antigens as an integral part of the humoral immune response to pathogenic microorganisms. Immunol. Rev. 176: 154-170.
2. Martin, F., and J. F. Kearney. 2002. Marginal-zone B cells. Nat. Rev. Immunol. 2: 323-335. (Pubitemid 37328755)
3. Kraal, G. 1992. Cells in the marginal zone of the spleen. Int. Rev. Cytol. 132: 31-74.
4. Kraal, G., K. Schornagel, P. R. Streeter, B. Holzmann, and E. C. Butcher. 1995. Expression of the mucosal vascular addressin, MAdCAM-1, on sinus-lining cells in the spleen. Am. J. Pathol. 147: 763-771.
5. Cinamon, G., M. A. Zachariah, O. M. Lam, F. W. Foss, Jr., and J. G. Cyster. 2008. Follicular shuttling of marginal zone B cells facilitates antigen transport. Nat. Immunol. 9: 54-62. (Pubitemid 350286204)
6. Kraal, G. 2008. Antigens take the shuttle. Nat. Immunol. 9: 11-12. (Pubitemid 350286196)
7. Guinamard, R., M. Okigaki, J. Schlessinger, and J. V. Ravetch. 2000. Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response. Nat. Immunol. 1: 31-36.
8. Shriner, A. K., H. Liu, G. Sun, M. Guimond, and K. R. Alugupalli. 2010. IL-7-dependent B lymphocytes are essential for the anti-polysaccharide response and protective immunity to Streptococcus pneumoniae. J. Immunol. 185: 525-531.
9. Li, S., Y. Yan, Y. Lin, D. M. Bullens, O. Rutgeerts, J. Goebels, C. Segers, L. Boon, A. Kasran, R. De Vos, et al. 2007. Rapidly induced, T-cell independent xenoantibody production is mediated by marginal zone B cells and requires help from NK cells. Blood 110: 3926-3935. (Pubitemid 350248448)
10. Yang, Y. G., and M. Sykes. 2007. Xenotransplantation: current status and a perspective on the future. Nat. Rev. Immunol. 7: 519-531. (Pubitemid 46987781)
11. Sprangers, B., M. Waer, and A. D. Billiau. 2008. Xenotransplantation: where are we in 2008? Kidney Int. 74: 14-21. (Pubitemid 351841894)
12. Ohdan, H., K. G. Swenson, H. S. Kruger Gray, Y. G. Yang, Y. Xu, A. D. Thall, and M. Sykes. 2000. Mac-1-negative B-1b phenotype of natural antibody-producing cells, including those responding to Gal alpha 1,3Gal epitopes in alpha 1,3-galactosyltransferase-deficient mice. J. Immunol. 165: 5518-5529.
13. Haas, K. M., J. C. Poe, D. A. Steeber, and T. F. Tedder. 2005. B-1a and B-1b cells exhibit distinct developmental requirements and have unique functional roles in innate and adaptive immunity to S. pneumoniae. Immunity 23: 7-18. (Pubitemid 41019653)
14. Hsu, M. C., K. M. Toellner, C. G. Vinuesa, and I. C. Maclennan. 2006. B cell clones that sustain long-term plasmablast growth in T-independent extrafollicular antibody responses. Proc. Natl. Acad. Sci. USA 103: 5905-5910.
15. Martin, F., A. M. Oliver, and J. F. Kearney. 2001. Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens. Immunity 14: 617-629. (Pubitemid 32520872)
16. Martin, F., and J. F. Kearney. 2001. B1 cells: similarities and differences with other B cell subsets. Curr. Opin. Immunol. 13: 195-201. (Pubitemid 32176039)
17. Moore, T. A., U. Von Freeden-Jeffry, R. Murray, and A. Zlotnik. 1996. Inhibition of gamma delta T cell development and early thymocyte maturation in IL-7-/-mice. J. Immunol. 157: 2366-2373. (Pubitemid 126450446)
18. Kikuchi, K., H. Kasai, A. Watanabe, A. Y. Lai, and M. Kondo. 2008. IL-7 specifies B cell fate at the common lymphoid progenitor to pre-proB transition stage by maintaining early B cell factor expression. J. Immunol. 181: 383-392.
19. Dias, S., H. Silva, Jr., A. Cumano, and P. Vieira. 2005. Interleukin-7 is necessary to maintain the B cell potential in common lymphoid progenitors. J. Exp. Med. 201: 971-979. (Pubitemid 40524466)
20. Carvalho, T. L., T. Mota-Santos, A. Cumano, J. Demengeot, and P. Vieira. 2001. Arrested B lymphopoiesis and persistence of activated B cells in adult interleukin 7(-/)- mice. J. Exp. Med. 194: 1141-1150. (Pubitemid 32995783)
21. Ferguson, A. R., M. E. Youd, and R. B. Corley. 2004. Marginal zone B cells transport and deposit IgM-containing immune complexes onto follicular dendritic cells. Int. Immunol. 16: 1411-1422. (Pubitemid 39341554)
22. Oliver, A. M., F. Martin, and J. F. Kearney. 1999. IgMhighCD21high lymphocytes enriched in the splenic marginal zone generate effector cells more rapidly than the bulk of follicular B cells. J. Immunol. 162: 7198-7207. (Pubitemid 29277691)
23. Yan, Y., E. Verbeken, L. Yu, O. Rutgeerts, J. Goebels, C. Segers, Y. Lin, and M. Waer. 2005. Effects of a short course of leflunomide on T-independent B-lymphocyte xenoreactivity and on susceptibility of xenografts to acute or chronic rejection. Transplantation 79: 135-141, discussion 133-134.
24. Vora, K. A., E. Nichols, G. Porter, Y. Cui, C. A. Keohane, R. Hajdu, J. Hale, W. Neway, D. Zaller, and S. Mandala. 2005. Sphingosine 1-phosphate receptor agonist FTY720-phosphate causes marginal zone B cell displacement. J. Leukoc. Biol. 78: 471-480. (Pubitemid 41061319)
25. Cinamon, G., M. Matloubian, M. J. Lesneski, Y. Xu, C. Low, T. Lu, R. L. Proia, and J. G. Cyster. 2004. Sphingosine 1-phosphate receptor 1 promotes B cell localization in the splenic marginal zone. Nat. Immunol. 5: 713-720. (Pubitemid 39023303)
26. Nolte, M. A., R. Arens, M. Kraus, M. H. Van Oers, G. Kraal, R. A. Van Lier, and R. E. Mebius. 2004. B cells are crucial for both development and maintenance of the splenic marginal zone. J. Immunol. 172: 3620-3627. (Pubitemid 38337944)
27. You, Y., H. Zhao, Y. Wang, and R. H. Carter. 2009. Cutting edge: primary and secondary effects of CD19 deficiency on cells of the marginal zone. J. Immunol. 182: 7343-7347.
28. Chen, Y., T. Pikkarainen, O. Elomaa, R. Soininen, T. Kodama, G. Kraal, and K. Tryggvason. 2005. Defective microarchitecture of the spleen marginal zone and impaired response to a thymus-independent type 2 antigen in mice lacking scavenger receptors MARCO and SR-A. J. Immunol. 175: 8173-8180. (Pubitemid 41798381)
29. Erlandsson, L., S. Licence, F. Gaspal, S. Bell, P. Lane, A. E. Corcoran, and I. L. Ma° rtensson. 2004. Impaired B-1 and B-2 B cell development and atypical splenic B cell structures in IL-7 receptor-deficient mice. Eur. J. Immunol. 34: 3595-3603. (Pubitemid 40012177)
30. Ochsenbein, A. F., D. D. Pinschewer, B. Odermatt, M. C. Carroll, H. Hengartner, and R. M. Zinkernagel. 1999. Protective T cell-independent antiviral antibody responses are dependent on complement. J. Exp. Med. 190: 1165-1174. (Pubitemid 29496509)
31. Jensen, C. T., S. Kharazi, C. Böiers, M. Cheng, A. Lübking, E. Sitnicka, and S. E. Jacobsen. 2008. FLT3 ligand and not TSLP is the key regulator of IL-7-independent B-1 and B-2 B lymphopoiesis. Blood 112: 2297-2304.
32. Hunte, B. E., S. Hudak, D. Campbell, Y. Xu, and D. Rennick. 1996. flk2/flt3 ligand is a potent cofactor for the growth of primitive B cell progenitors. J. Immunol. 156: 489-496.
33. Guay, H. M., R. Mishra, R. L. Garcea, R. M. Welsh, and E. Szomolanyi-Tsuda. 2009. Generation of protective T cell-independent antiviral antibody responses in SCID mice reconstituted with follicular or marginal zone B cells. J. Immunol. 183: 518-523.