B Cells Are Crucial for Both Development and Maintenance of the Splenic Marginal Zone

Journal of Immunology

Volumn 172, Issue 6, 2004, Pages 3620-3627

  Nolte, Martijn A ^a,b   Arens, Ramon ^b   Kraus, Manfred ^c   Van Oers, Marinus H J ^b   Kraal, Georg ^a   Van Lier, René A W ^b   Mebius, Reina E ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; BETA GALACTOSIDASE; CD27 ANTIGEN; CD70 ANTIGEN; MUCOSAL ADDRESSIN CELL ADHESION MOLECULE 1; PROTEIN IGALPHA; PROTEIN SUBUNIT; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ANTIGEN PRESENTATION; ARTICLE; B LYMPHOCYTE; BACTERIAL INFECTION; CONTROLLED STUDY; HUMAN; IMMUNITY; LYMPHOCYTE DEPLETION; LYMPHOID TISSUE; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; SPLEEN; SPLEEN CELL; SPLEEN MARGINAL ZONE; TRANSGENIC MOUSE;

EID: 1542514724     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.172.6.3620     Document Type: Article

References (52)

1. Steiniger, B., and P. Barth, 2000. Microanatomy and function of the spleen. Adv. Anat. Embryol. Cell. Biol. 151:111.
2. Schmidt, E. E., I. C. MacDonald, and A. C. Groom. 1988. Microcirculatory pathways in normal human spleen, demonstrated by scanning electron microscopy of corrosion casts. Am. J. Anat. 181:253.
3. Kraal, G., K. Schornagel, P. R. Streeter, B. Holzmann, and E. C. Butcher. 1995. Expression of the mucosal vascular addressin, MAdCAM-1, on sinus-lining cells in the spleen. Am. J. Pathol. 147:763.
4. Kraal, G. 1992. Cells in the marginal zone of the spleen. Int. Rev. Cytol. 132:31.
5. Van den Eertwegh, A. J., W. J. Boersma, and E. Claassen. 1992. Immunological functions and in vivo cell-cell interactions of T cells in the spleen. Crit. Rev. Immunol. 11-337.
6. Rugh, R. 1968. The Mouse: Its Reproduction and Development. Burgess Publishing, Minneapolis.
7. Sasaki, K., and G. Matsumura. 1988. Spleen lymphocytes and haemopoiesis in the mouse embryo. J. Anat. 160:27.
8. Friedberg, S. H., and I. L. Weissman. 1974. Lymphoid tissue architecture. II. Ontogeny of peripheral T and B cells in mice: evidence against Peyer's patches as the site of generation of B cells. J. Immunol. 113:1477.
9. -cells to colonize lymph nodes. Proc. Natl. Acad. Sci. USA 93:11019.
10. Kraal, G., M. Janse, and E. Claassen. 1988. Marginal metallophilic macrophages in the mouse spleen: effects of neonatal injections of MOMA-1 antibody on the humoral immune response. Immunol. Lett. 17:139.
11. Morris, L., P. R. Crocker, M. Hill, and S. Gordon. 1992. Developmental regulation of sialoadhesin (sheep erythrocyte receptor), a macrophage-cell interaction molecule expressed in lymphohemopoietic tissues. Dev. Immunol. 2:7.
12. Takeya, M., and K. Takahashi. 1992. Ontogenic development of macrophage subpopulations and Ia-positive dendritic cells in fetal and neonatal rat spleen. J. Leukocyte Biol. 52:516.
13. Loder, F., B. Mutschler, R. J. Ray, C. J. Paige, P. Sideras, R. Torres, M. C. Lamers, and R. Carsetti. 1999. B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals. J. Exp. Med. 190:75.
14. Crowley, M. T., C. R. Reilly, and D. Lo. 1999. Influence of lymphocytes on the presence and organization of dendritic cell subsets in the spleen. J. Immunol. 163:4894.
15. Dingjan, G. M., A. Maas, M. C. Nawijn, L. Smit, J. S. Voerman, F. Grosveld, and R. W. Hendriks. 1998. Severe B cell deficiency and disrupted splenic architecture in transgenic mice expressing the E41K mutated form of Bruton's tyrosine kinase. EMBO J. 17:5309.
16. Maas, A., G. Dingjan, F. Grosveld, and R. W. Hendriks. 1999. Early arrest in B cell development in transgenic mice that express the E41K Bruton's tyrosine kinase mutant under the control of the CD19 promoter region. J. Immunol. 162: 6526.
17. Arens, R., K. Tesselaar, P. A. Baars, G. M. Van Schijndel, J. Hendriks, S. T. Pals, P. Krimpenfort, J. Borst, M. H. Van Oers, and R. A. Van Lier. 2001. Constitutive CD27/CD70 interaction induces expansion of effector-type T cells and results in IFN-γ-mediated B cell depletion. Immunity 15:801.
18. Kühn, R., F. Schwenk, M. Aguet, and K. Rajewsky. 1995. Inducible gene targeting in mice. Science 269:1427.
19. Hendriks, J., L. A. Gravestein, K. Tesselaar, R. A. van Lier, T. N. Schumacher, and J. Borst. 2000. CD27 is required for generation and long-term maintenance of T cell immunity. Nat. Immunol. 1:433.
20. Mombaerts, P., A. R. Clarke, M. A. Rudnicki, J. Iacomini, S. Itohara, J. J. Lafaille, L. Wang, Y. Ichikawa, R. Jaenisch, M. L. Hooper, et al. 1992. Mutations in T-cell antigen receptor genes α and β block thymocyte development at different stages. Nature 360:225.
21. De Togni, P., J. Goellner, N. H. Ruddle, P. R. Streeter, A. Fick, S. Mariathasan, S. C. Smith, R. Carlson, L. P. Shornick, and J. Strauss-Schoenberger. 1994. Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin. Science 264:703.
22. Kitamura, D., J. Roes, R. Kühn, and K. Rajewsky. 1991. A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene. Nature 350:423.
23. Heath, A. W., W. W. Wu, and M. C. Howard. 1994. Monoclonal antibodies to murine CD40 define two distinct functional epitopes. Eur. J. Immunol. 24:1828.
24. Browning, J. L., I. D. Sizing, P. Lawton, P. R. Bourdon, P. D. Rennert, G. R. Majeau, C. M. Ambrose, C. Hession, K. Miatkowski, D. A. Griffiths, et al. 1997. Characterization of lymphotoxin-αβ complexes on the surface of mouse lymphocytes. J. Immunol. 159:3288.
25. Lam, K., R. Kühn, and K. Rajewsky. 1997. In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death. Cell 90:1073.
26. Humphrey, J. H., and D. Grennan. 1981. Different macrophage populations distinguished by means of fluorescent polysaccharides. Eur. J. Immunol. 11:221.
27. van den Eertwegh, A. J., J. D. Laman, M. M. Schellekens, W. J. Boersma, and E. Claassen. 1992. Complement-mediated follicular localization of T-independent type-2 antigens: the role of marginal zone macrophages revisited. Eur. J. Immunol. 22:719.
28. Mackay, F., G. R. Majeau, P. Lawton, P. S. Hochman, and J. L. Browning. 1997. Lymphotoxin but not tumor necrosis factor functions to maintain splenic architecture and humoral responsiveness in adult mice. Eur. J. Immunol. 27:2033.
29. Worm, M., and R. S. Geha. 1994. CD40 ligation induces lymphotoxin αgene expression in human B cells. Int. Immunol. 6:1883.
30. Wiesmann, A., R. L. Phillips, M. Mojica, L. J. Pierce, A. E. Searles, G. J. Spangrude, and I. Lemischka. 2000. Expression of CD27 on murine hematopoietic stem and progenitor cells. Immunity 12:193.
31. Hao, Z., and K. Rajewsky. 2001. Homeostasis of peripheral B cells in the absence of B cell influx from the bone marrow. J. Exp. Med. 194:1151.
32. Guinamard, R., M. Okigaki, J. Schlessinger, and J. V. Ravetch. 2000. Absence of marginal zone B cells in Pyk-2 deficient mice defines their role in the humoral response. Nat. Immunol. 1:31.
33. Banks, T. A., B. T. Rouse, M. K. Kerley, P. J. Blair, V. L. Godfrey, N. A. Kuklin, D. M. Bouley, J. Thomas, S. Kanangat, and M. L. Mucenski. 1995. Lymphotoxin-α-deficient mice: effects on secondary lymphoid organ development and humoral immune responsiveness. J. Immunol. 155:1685.
34. Alimzhanov, M., D. Kuprash, M. Kosco-Vilbois, A. Luz, R. Turetskaya, A. Tarakhovsky, K. Rajewsky, S. Nedospasov, and K. Pfeffer. 1997. Abnormal development of secondary lymphoid tissues in lymphotoxin β-deficient mice. Proc. Natl. Acad. Sci. USA 94:9302.
35. Koni, P. A., R. Sacca, P. Lawton, J. L. Browning, N. H. Ruddle, and R. A. Flavell. 1997. Distinct roles in lymphoid organogenesis for lymphotoxins α and β revealed in lymphotoxin β-deficient mice. Immunity 6:491.
36. Futterer, A., K. Mink, A. Luz, M. H. Kosco-Vilbois, and K. Pfeffer. 1998. The lymphotoxin β receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues. Immunity 9:59.
37. Tumanov, A. V., D. V. Kuprash, M. A. Lagarkova, S. I. Grivennikov, K. Abe, A. N. Shakhov, L. N. Drutskaya, C. L. Stewart, A. V. Chervonsky, and S. A. Nedospasov. 2002. Distinct role of surface lymphotoxin expressed by B cells in the organization of secondary lymphoid tissues. Immunity 17:239.
38. Ngo, V. N., H. Korner, M. D. Gunn, K. N. Schmidt, D. S. Riminton, M. D. Cooper, J. L. Browning, J. D. Sedgwick, and J. G. Cyster. 1999. Lymphotoxin α/β and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen. J. Exp. Med. 189:403.
39. Ansel, K. M., V. N. Ngo, P. L. Hyman, S. A. Luther, R. Förster, J. D. Sedgwick, J. L. Browning, M. Lipp, and J. G. Cyster. 2000. A chemokine-driven positive feedback loop organizes lymphoid follicles. Nature 406:309.
40. Ngo, V. N., R. J. Cornall, and J. G. Cyster. 2001. Splenic T zone development is B cell dependent. J. Exp. Med. 194:1649.
41. Dejardin, E., N. M. Droin, M. Delhase, E. Haas, Y. Cao, C. Makris, Z. Li, M. Karin, C. F. Ware, and D. R. Green. 2002. The lymphotoxin-β receptor induces different patterns of gene expression via two NF-κB pathways. Immunity 17:525.
42. Sethna, M. P., L. van Parijs, A. H. Sharpe, A. K. Abbas, and G. J. Freeman. 1994. A negative regulatory function of B7 revealed in B7-1 transgenic mice. Immunity 1:415.
43. Van Parijs, L., M. P. Sethna, A. N. Schweitzer, F. Borriello, A. H. Sharpe, and A. K. Abbas. 1997. Functional consequences of dysregulated B7-1 (CD80) and B7-2 (CD86) expression in B or T lymphocytes of transgenic mice. J. Immunol. 159:5336.
44. Fournier, S., J. C. Rathmell, C. C. Goodnow, and J. P. Allison. 1997. T cell-mediated elimination of B7.2 transgenic B cells. Immunity 6:327.
45. Zhu, G., D. Flies, K. Tamada, Y. Sun, M. Rodriguez, Y. Fu, and L. Chen. 2001. Progressive depletion of peripheral B lymphocytes in 4-1BB (CD137) ligand/I-Eα-transgenic mice. J. Immunol. 167:2671.
46. Young, H. A., D. M. Klinman, D. A. Reynolds, K. J. Grzegorzewski, A. Nii, J. M. Ward, R. T. Winkler-Pickett, J. R. Ortaldo, J. J. Kenny, and K. L. Komschlies. 1997. Bone marrow and thymus expression of interferon-γ results in severe B-cell lineage reduction, T-cell lineage alterations, and hematopoietic progenitor deficiencies. Blood 89:583.
47. Alexander, W. S., R. Starr, J. E. Fenner, C. L. Scott, E. Handman, N. S. Sprigg, J. E. Corbin, A. L. Cornish, R. Darwiche, C. M. Owczarek, et al. 1999. SOCSI is a critical inhibitor of interferon γ signaling and prevents the potentially fatal neonatal actions of this cytokine. Cell 98:597.
48. Seiler, P., P. Aichele, B. Odermatt, H. Hengartner, R. M. Zinkernagel, and R. A. Schwendener. 1997. Crucial role of marginal zone macrophages and marginal zone metallophils in the clearance of lymphocytic choriomeningitis virus infection. Eur. J. Immunol. 27:2626
49. Fehr, T., C. Lopez-Macias, B. Odermatt, R. M. Torres, D. B. Schubart, T. L. O'Keefe, P. Matthias, H. Hengartner, and R. M. Zinkernagel. 2000. Correlation of anti-viral B cell responses and splenic morphology with expression of B cell-specific molecules. Int. Immunol. 12:1275.
50. Oehen, S., B. Odermatt, U. Karrer, H. Hengartner, R. Zinkernagel, and C. Lopez-Macias. 2002. Marginal zone macrophages and immune responses against viruses. J. Immunol. 169:1453.
51. Von Mehren, M., G. P. Adams, and L. M. Weiner. 2003. Monoclonal antibody therapy for cancer. Annu. Rev. Med. 54:343.
52. Silverman, G. J., and S. Weisman. 2003. Rituximab therapy and autoimmune disorders: prospects for anti-B cell therapy. Arthritis Rheum. 48:1484.