Improving a natural CaMKII inhibitor by random and rational design

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Coultrap, Steven J ^a   Bayer, K Ulrich ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALMODULIN; ALANINE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE I; PEPTIDE; PROTEIN KINASE INHIBITOR; SERINE;

ARTICLE; BINDING SITE; CONTROLLED STUDY; GENE MUTATION; GENE SEQUENCE; INTRACELLULAR SIGNALING; MUTAGENESIS; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; AMINO ACID SEQUENCE; CHEMISTRY; DRUG ANTAGONISM; DRUG DESIGN; DRUG EFFECT; ENZYME SPECIFICITY; GENETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; PHOSPHORYLATION; SOLUTION AND SOLUBILITY;

ALANINE; AMINO ACID SEQUENCE; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; DRUG DESIGN; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTATION; PEPTIDES; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; SERINE; SOLUTIONS; SUBSTRATE SPECIFICITY;

EID: 80053457127     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025245     Document Type: Article

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