Constitutive expression of insulin receptor substrate (irs)-1 inhibits myogenic differentiation through nuclear exclusion of foxo1 in l6 myoblasts

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Hakuno, Fumihiko ^a   Yamauchi, Yoko ^b,d   Kaneko, Gen ^a   Yoneyama, Yosuke ^a   Nakae, Jun ^c   Chida, Kazuhiro ^a   Kadowaki, Tatsuhiko ^b   Yamanouchi, Keitaro ^a   Nishihara, Masugi ^a   Takahashi, Shin Ichiro ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b NAGOYA UNIVERSITY   (Japan)

^c KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d Hair Clinic Reve21 Corporation   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN RECEPTOR SUBSTRATE 1; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHR; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, RAT; INSULIN RECEPTOR SUBSTRATE; NERVE PROTEIN; SOMATOMEDIN C;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL NUCLEUS; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; MUSCLE DEVELOPMENT; MYOBLAST; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RAT; SATELLITE CELL; ANIMAL; CYTOLOGY; DOMINANT GENE; DRUG EFFECT; ENZYME ACTIVATION; GENETICS; METABOLISM; MUTATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SKELETAL MUSCLE SATELLITE CELL;

ANIMALS; CELL DIFFERENTIATION; CELL NUCLEUS; CELL PROLIFERATION; ENZYME ACTIVATION; FORKHEAD TRANSCRIPTION FACTORS; GENES, DOMINANT; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN-LIKE GROWTH FACTOR I; MUSCLE DEVELOPMENT; MUTATION; MYOBLASTS; NERVE TISSUE PROTEINS; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-AKT; RATS; SATELLITE CELLS, SKELETAL MUSCLE; SIGNAL TRANSDUCTION;

EID: 80053440021     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025655     Document Type: Article

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