L-tryptophan-mediated enhancement of susceptibility to nonalcoholic fatty liver disease is dependent on the mammalian target of rapamycin

Journal of Biological Chemistry

Volumn 286, Issue 40, 2011, Pages 34800-34808

  Osawa, Yosuke ^a   Kanamori, Hiromitsu ^a   Seki, Ekihiro ^b   Hoshi, Masato ^a   Ohtaki, Hirofumi ^a   Yasuda, Yoichi ^a   Ito, Hiroyasu ^a   Suetsugu, Atsushi ^a   Nagaki, Masahito ^a   Moriwaki, Hisataka ^a   Saito, Kuniaki ^c   Seishima, Mitsuru ^a  

^a GIFU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC AMINO ACID; DECARBOXYLASES; HEPATIC STEATOSIS; HEPATOCYTES; HYDROXYPROLINE CONTENT; L-TRYPTOPHAN; LIPID METABOLISMS; LIVER DISEASE; MAMMALIAN TARGET; MAMMALIAN TARGET OF RAPAMYCIN (MTOR); NON-ALCOHOLIC FATTY LIVER DISEASE; RAPAMYCIN;

ANTIBIOTICS; BODY FLUIDS; FATTY ACIDS; MAMMALS; METABOLISM; PHOSPHORYLATION;

AMINO ACIDS;

4 HYDROXYNONENAL; ADENOVIRUS VECTOR; ALANINE AMINOTRANSFERASE; AROMATIC LEVO AMINO ACID DECARBOXYLASE; HYDROXYPROLINE; MAMMALIAN TARGET OF RAPAMYCIN; RAPAMYCIN; SEROTONIN; TRYPTOPHAN;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; AMINO ACID SYNTHESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE EXACERBATION; DISEASE PREDISPOSITION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FATTY LIVER; LIPID DIET; LIPID STORAGE; MALE; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN FUNCTION; SEROTONIN BLOOD LEVEL;

ADENOVIRIDAE; ANIMAL FEED; ANIMALS; AROMATIC-L-AMINO-ACID DECARBOXYLASES; FATTY LIVER; FIBROSIS; FRUCTOSE; GENETIC PREDISPOSITION TO DISEASE; HEPATOCYTES; KYNURENINE; LIPIDS; MALE; MICE; MICE, INBRED C57BL; SEROTONIN; TOR SERINE-THREONINE KINASES; TRIGLYCERIDES; TRYPTOPHAN;

MAMMALIA;

EID: 80053433530     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.235473     Document Type: Article

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