The absence of IDO upregulates type I IFN production, resulting in suppression of viral replication in the retrovirus-infected mouse

Journal of Immunology

Volumn 185, Issue 6, 2010, Pages 3305-3312

  Hoshi, Masato ^a   Saito, Kuniaki ^a,b   Hara, Akira ^a   Taguchi, Ayako ^a   Ohtaki, Hirofumi ^a   Tanaka, Ryo ^a   Fujigaki, Hidetsugu ^d   Osawa, Yosuke ^a   Takemura, Masao ^a   Matsunami, Hidetoshi ^c   Ito, Hiroyasu ^a   Seishima, Mitsuru ^a  

^a GIFU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c Matsunami General Hospital   (Japan)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL PROLIFERATION; HISTOPATHOLOGY; INTERFERON PRODUCTION; MALE; MOUSE; NONHUMAN; PLASMACYTOID DENDRITIC CELL; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RETROVIRUS INFECTION; SURVIVAL RATE; TOXOPLASMA GONDII; TOXOPLASMOSIS; VIRUS NEUTRALIZATION; VIRUS REPLICATION; WESTERN BLOTTING;

ADAPTIVE IMMUNITY; ANIMALS; DOWN-REGULATION; IMMUNITY, INNATE; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; INTERFERON TYPE I; LEUKEMIA VIRUS, MURINE; LEUKEMIA, EXPERIMENTAL; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RETROVIRIDAE INFECTIONS; SIGNAL TRANSDUCTION; TUMOR VIRUS INFECTIONS; UP-REGULATION; VIRUS REPLICATION;

EID: 78649809669     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0901150     Document Type: Article

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