In vitro insulin secretion by pancreatic tissue from infants with diazoxide-resistant congenital hyperinsulinism deviates from model predictions

Journal of Clinical Investigation

Volumn 121, Issue 10, 2011, Pages 3932-3942

  Henquin, Jean Claude ^a   Nenquin, Myriam ^a   Sempoux, Christine ^a   Guiot, Yves ^a   Bellanné Chantelot, Christine ^b   Otonkoski, Timo ^c   De Lonlay, Pascale ^d   Nihoul Fékété, Claire ^e   Rahier, Jacques ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^c UNIVERSITY OF HELSINKI   (Finland)

^d UNIVERSITÉ PARIS DESCARTES   (France)

^e HÔPITAL NECKER ENFANTS MALADES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DIAZOXIDE; GLUCOSE; INSULIN; TOLBUTAMIDE;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; HUMAN; HUMAN TISSUE; IN VITRO STUDY; INFANT; INSULIN RELEASE; PANCREAS ISLET; PERSISTENT HYPERINSULINEMIC HYPOGLYCEMIA OF INFANCY; PRIORITY JOURNAL; TREATMENT RESPONSE;

ATP-BINDING CASSETTE TRANSPORTERS; CYCLIN-DEPENDENT KINASE INHIBITOR P57; DIAZOXIDE; DRUG RESISTANCE; HUMANS; INFANT; INSULIN; ISLETS OF LANGERHANS; MODELS, BIOLOGICAL; MUTATION; PERSISTENT HYPERINSULINEMIA HYPOGLYCEMIA OF INFANCY; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RECEPTORS, DRUG; TOLBUTAMIDE;

EID: 80053411257     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI58400     Document Type: Article

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