Somatostatin release, electrical activity, membrane currents and exocytosis in human pancreatic delta cells

Diabetologia

Volumn 52, Issue 8, 2009, Pages 1566-1578

  Braun, M ^a   Ramracheya, R ^a   Amisten, S ^a   Bengtsson, M ^a   Moritoh, Y ^a   Zhang, Q ^a   Johnson, P R ^b   Rorsman, P ^a  

^a CHURCHILL HOSPITAL   (United Kingdom)

^b JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

Electrophysiology; Exocytosis; Hormone secretion; Human islets; Islet physiology; Pancreatic delta cells; Patch clamp; Somatostatin

Indexed keywords

4 AMINOPYRIDINE; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; BARIUM; CALCIUM CHANNEL; DIAZOXIDE; GLUCOSE; INWARDLY RECTIFYING POTASSIUM CHANNEL; ION CHANNEL; ISRADIPINE; NNC 550396; OMEGA AGATOXIN; POTASSIUM CHANNEL BLOCKING AGENT; SOMATOSTATIN; STROMATOXIN; TETRODOTOXIN; TETRYLAMMONIUM; TOLBUTAMIDE; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL;

ACTION POTENTIAL; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; ELECTRIC ACTIVITY; ELECTRIC POTENTIAL; ELECTROPHYSIOLOGY; EXOCYTOSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; MEMBRANE CURRENT; MEMBRANE POTENTIAL; PANCREAS ISLET; PANCREAS ISLET DELTA CELL; PRIORITY JOURNAL; SODIUM CURRENT; SOMATOSTATIN RELEASE;

DIAZOXIDE; EXOCYTOSIS; GLUCOSE; HUMANS; ISLETS OF LANGERHANS; MEMBRANE POTENTIALS; PATCH-CLAMP TECHNIQUES; PYRIMIDINES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SOMATOSTATIN; SOMATOSTATIN-SECRETING CELLS; TOLBUTAMIDE;

EID: 67650686039     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-009-1382-z     Document Type: Article

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