Niflumic acid-sensitive ion channels play an important role in the induction of glucose-stimulated insulin secretion by cyclic AMP in mice

Diabetologia

Volumn 52, Issue 5, 2009, Pages 863-872

  Fujimoto, W ^a   Miki, T ^a,b   Ogura, T ^b   Zhang, M ^c   Seino, Y ^a,e   Satin, L S ^c,d   Nakaya, H ^b   Seino, S ^a,f  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b CHIBA UNIVERSITY   (Japan)

^c VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^e NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^f JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

cAMP; GLP 1; Incretin; Insulin secretion; KATP channel; Kir6.2; Niflumic acid

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; CYCLIC AMP; GLIBENCLAMIDE; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; NIFLUMIC ACID; PANCRELIPASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CLONE; CELL ISOLATION; CONTROLLED STUDY; ELECTROPHYSIOLOGY; FEMALE; GLUCOSE BLOOD LEVEL; INHIBITION KINETICS; INSULIN RELEASE; MALE; MEMBRANE DEPOLARIZATION; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS PERFUSION; PRIORITY JOURNAL; WILD TYPE;

8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ANIMALS; CELL LINE, TUMOR; CYCLIC AMP; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DNA PRIMERS; GLUCOSE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; INSULIN; INSULINOMA; INTESTINE, SMALL; ION CHANNELS; MICE; MICE, KNOCKOUT; NIFLUMIC ACID; PANCREAS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 64149095161     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-009-1306-y     Document Type: Article

References (29)

1. JC Henquin 2000 Triggering and amplifying pathways of regulation of insulin secretion by glucose Diabetes 49 1751 1760
2. PE MacDonald JW Joseph P Rorsman 2005 Glucose-sensing mechanisms in pancreatic beta-cells Philos Trans R Soc Lond B Biol Sci 360 2211 2225
3. ATP channels as metabolic sensors in acute metabolic changes J Mol Cell Cardiol 38 917 925
4. JJ Holst J Gromada 2004 Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans Am J Physiol Endocrinol Metab 287 E199 E206
5. DJ Drucker 2006 The biology of incretin hormones Cell Metab 3 153 165
6. GC Weir S Mojsov GK Hendrick JF Habener 1989 Glucagon-like peptide I (7-37) actions on endocrine pancreas Diabetes 38 338 342
7. ATP channel-deficient mice Proc Natl Acad Sci USA 95 10402 10406
8. ATP channel-independent regulation of insulin secretion J Biol Chem 275 9270 9277
9. C Shiota O Larsson KD Shelton 2002 Sulfonylurea receptor type 1 knock-out mice have intact feeding-stimulated insulin secretion despite marked impairment in their response to glucose J Biol Chem 277 37176 37183
10. T Miki K Minami H Shinozaki 2005 Distinct effects of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 on insulin secretion and gut motility Diabetes 54 1056 1063
11. + channel activity Diabetes 48 2001 2006
12. H Ishihara P Maechler A Gjinovci PL Herrera CB Wollheim 2003 Islet beta-cell secretion determines glucagon release from neighbouring alpha-cells Nat Cell Biol 5 330 335
13. 2+ in mouse islets of Langerhans Am J Physiol 266 E852 E862
14. 2+ stores activates a maitotoxin-sensitive nonselective cationic current in beta-cells J Biol Chem 269 32055 32058
15. - channel current that is activated by cell swelling, cAMP, and glyburide in insulin-secreting cells Diabetes 44 1461 1466
16. MS Stalvey C Muller DA Schatz 2006 Cystic fibrosis transmembrane conductance regulator deficiency exacerbates islet cell dysfunction after beta-cell injury Diabetes 55 1939 1945
17. TJ Jentsch V Stein F Weinreich AA Zdebik 2002 Molecular structure and physiological function of chloride channels Physiol Rev 82 503 568
18. 2+ release by flufenamic acid and other blockers of the non-selective cation channel FEBS Lett 296 245 248
19. i oscillations in transgenically derived beta-cells J Biol Chem 273 10402 10410
20. 2+ signal J Biol Chem. 282 14768 14776
21. L Best 2002 Study of a glucose-activated anion-selective channel in rat pancreatic beta-cells Pflugers Arch 445 97 104
22. A Liantonio A Picollo E Babini 2006 Activation and inhibition of kidney CLC-K chloride channels by fenamates Mol Pharmacol 69 165 173
23. M Ritter A Ravasio M Jakab 2003 Cell swelling stimulates cytosol to membrane transposition of ICln J Biol Chem 278 50163 50174
24. MM Byrne J Sturis K Clément 1994 Insulin secretory abnormalities in subjects with hyperglycemia due to glucokinase mutations J Clin Invest 93 1120 1130
25. MM Byrne J Sturis KS Polonsky 1995 Insulin secretion and clearance during low-dose graded glucose infusion Am J Physiol 268 E21 E27
26. NM Doliba W Qin MZ Vatamaniuk 2004 Restitution of defective glucose-stimulated insulin release of sulfonylurea type 1 receptor knockout mice by acetylcholine Am J Physiol Endocrinol Metab 286 E834 E843
27. MA Nauck MM Heimesaat C Orskov JJ Holst R Ebert W Creutzfeldt 1993 Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus J Clin Invest 91 301 307
28. GG Holz 4th WM Kuhtreiber JF Habener 1993 Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon-like peptide-1(7-37) Nature 361 362 365
29. H Suzuki M Fukushima S Okamoto 2005 Effects of thorough mastication on postprandial plasma glucose concentrations in nonobese Japanese subjects Metabolism 54 1593 1599