SCOPUS 정보 검색 플랫폼

Volumn 6, Issue 10, 2011, Pages 1781-1788

The Metabolic Fate of isoCombretastatin A-4 in Human Liver Microsomes: Identification, Synthesis and Biological Evaluation of Metabolites

(10) Soussi, Mohamed Ali a Aprile, Silvio b Messaoudi, Samir a Provot, Olivier a DelGrosso, Erika b Bignon, Jérôme c Dubois, Joëlle c Brion, Jean Daniel a Grosa, Giorgio b Alami, Mouad a

a UNIVERSITÉ PARIS SACLAY (France)

b UNIVERSITY OF EASTERN PIEDMONT (Italy)

c CNRS (France)

Author keywords

Anticancer agents; Cytotoxicity; Drug metabolism; Isocombretastatin A 4; Tubulin

Indexed keywords

2 HYDROXY 5 [1 (3,4,5 TRIMETHOXYPHENYL)ETHENYL]PHENOL; 2 METHOXY 5 [1 (4 HYDROXY 3,5 DIMETHOXYPHENYL)ETHENYL]PHENOL; 2 METHOXY 5 [1 (5 HYDROXY 3,4 DIMETHOXYPHENYL)ETHENYL]PHENOL; 3 HYDROXY 2 METHOXY 5 [1 (3,4,5 TRIMETHOXYPHENYL)ETHENYL]PHENOL; 4 HYDROXY 2 METHOXY 5' [1 (3,4,5 TRIMETHOXYPHENYL)ETHENYL]PHENOL; 4 QUINONE; ANTIMITOTIC AGENT; COMBRETASTATIN A4; DRUG METABOLITE; EPOXIDE; ISOCOMBRETASTATIN A4; O DEMETHYLASE; TUBULIN; UNCLASSIFIED DRUG;

ARTICLE; BIOLOGICAL ACTIVITY; CANCER INHIBITION; CELL PROLIFERATION; CELL VIABILITY; COLON CARCINOMA; CONTROLLED STUDY; CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYDROXYLATION; LIVER MICROSOME; LIVER MICROSOME METABOLISM; MICROTUBULE ASSEMBLY; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; HUMANS; HYDROXYLATION; ISOMERISM; MICROSOMES, LIVER; STILBENES; TUBULIN; TUBULIN MODULATORS;

EID: 80053391280 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.201100193 Document Type: Article

Times cited : (15)

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