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Volumn 35, Issue 12, 2007, Pages 2252-2261

In vitro metabolism study of combretastatin A-4 in rat and human liver microsomes

Author keywords

[No Author keywords available]

Indexed keywords

COMBRETASTATIN A4; QUINONE DERIVATIVE; STILBENE DERIVATIVE;

EID: 36349000649     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.107.016998     Document Type: Article
Times cited : (102)

References (25)
  • 3
    • 33947474585 scopus 로고
    • Chemical and enzymatic routes to methoxydopamines
    • Daly J, Horner L, and Witkop B (1961) Chemical and enzymatic routes to methoxydopamines. J Am Chem Soc 83:4787-4791.
    • (1961) J Am Chem Soc , vol.83 , pp. 4787-4791
    • Daly, J.1    Horner, L.2    Witkop, B.3
  • 4
    • 0030951899 scopus 로고    scopus 로고
    • Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature
    • Dark GG, Hill SA, Prise VE, Tozer GM, Pettit GR, and Chaplin DJ (1997) Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature. Cancer Res 57:1829-1834.
    • (1997) Cancer Res , vol.57 , pp. 1829-1834
    • Dark, G.G.1    Hill, S.A.2    Prise, V.E.3    Tozer, G.M.4    Pettit, G.R.5    Chaplin, D.J.6
  • 5
    • 0037096814 scopus 로고    scopus 로고
    • A phase I pharmacokinetic and translational study of the novel vascular targeting agent combretastatin A-4 phosphate on a single-dose intravenous schedule in patients with advanced cancer
    • Dowlati A, Robertson K, Cooney M, Petros WP, Stratford M, Jesberger J, Rafie N, Overmoyer B, Makkar V, Stambler B, et al. (2002) A phase I pharmacokinetic and translational study of the novel vascular targeting agent combretastatin A-4 phosphate on a single-dose intravenous schedule in patients with advanced cancer. Cancer Res 62:3408-3416.
    • (2002) Cancer Res , vol.62 , pp. 3408-3416
    • Dowlati, A.1    Robertson, K.2    Cooney, M.3    Petros, W.P.4    Stratford, M.5    Jesberger, J.6    Rafie, N.7    Overmoyer, B.8    Makkar, V.9    Stambler, B.10
  • 7
    • 2442565699 scopus 로고    scopus 로고
    • Identification of 2,3-diaminophenazine and of o-benzoquinone dioxime as the major in vitro metabolites of benzofuroxan
    • Grosa G, Galli U, Rolando B, Fruttero R, Gervasio G, and Gasco A (2004) Identification of 2,3-diaminophenazine and of o-benzoquinone dioxime as the major in vitro metabolites of benzofuroxan. Xenobiotica 34:345-352.
    • (2004) Xenobiotica , vol.34 , pp. 345-352
    • Grosa, G.1    Galli, U.2    Rolando, B.3    Fruttero, R.4    Gervasio, G.5    Gasco, A.6
  • 8
    • 0032758736 scopus 로고    scopus 로고
    • In vivo and in vitro evaluation of combretastatin-A4 and its sodium phosphate prodrug
    • Grosios K, Holwell SE, McGown AT, Pettit GR, and Bibby MC (1999) In vivo and in vitro evaluation of combretastatin-A4 and its sodium phosphate prodrug. Br J Cancer 81:1318-1327.
    • (1999) Br J Cancer , vol.81 , pp. 1318-1327
    • Grosios, K.1    Holwell, S.E.2    McGown, A.T.3    Pettit, G.R.4    Bibby, M.C.5
  • 9
    • 0007924787 scopus 로고
    • Selective demethylations in 2,3,4-trimethoxyaryl carbonyl compounds
    • Kaisalo L, Latvala A, and Hase T (1986) Selective demethylations in 2,3,4-trimethoxyaryl carbonyl compounds. Synth Commun 16:645-648.
    • (1986) Synth Commun , vol.16 , pp. 645-648
    • Kaisalo, L.1    Latvala, A.2    Hase, T.3
  • 12
    • 0023801309 scopus 로고
    • Interactions of tubulin with potent natural and synthetic analogs of antimitotic agent combretastatin: A structure-activity study
    • Lin CM, Singh SB, Chu PS, Dempcy RO, Schmidt JM, Pettit GR, and Hamel E (1988) Interactions of tubulin with potent natural and synthetic analogs of antimitotic agent combretastatin: a structure-activity study. Mol Pharmacol 34:200-208.
    • (1988) Mol Pharmacol , vol.34 , pp. 200-208
    • Lin, C.M.1    Singh, S.B.2    Chu, P.S.3    Dempcy, R.O.4    Schmidt, J.M.5    Pettit, G.R.6    Hamel, E.7
  • 13
    • 33845286942 scopus 로고    scopus 로고
    • Vascular disrupting agents
    • Lippert JW (2007) Vascular disrupting agents. Bioorg Med Chem 15:605-615.
    • (2007) Bioorg Med Chem , vol.15 , pp. 605-615
    • Lippert, J.W.1
  • 14
    • 33748806029 scopus 로고    scopus 로고
    • Drugs under development for the treatment of breast cancer: Combretastatin A-4 phosphate
    • Mealy NE, Lupone B, and Balcell M (2006) Drugs under development for the treatment of breast cancer: combretastatin A-4 phosphate. Drug Fut 31:547-548.
    • (2006) Drug Fut , vol.31 , pp. 547-548
    • Mealy, N.E.1    Lupone, B.2    Balcell, M.3
  • 15
    • 0024510343 scopus 로고
    • Structural and biochemical comparison of the antimitotic agents colchicine, combretastatin-A4 and amphetinile
    • McGown AT and Fox BV (1989) Structural and biochemical comparison of the antimitotic agents colchicine, combretastatin-A4 and amphetinile. Anticancer Drug Des 3:249-254.
    • (1989) Anticancer Drug Des , vol.3 , pp. 249-254
    • McGown, A.T.1    Fox, B.V.2
  • 16
    • 0000655409 scopus 로고
    • The carbon monoxide binding pigment of liver microsomes
    • Omura T and Sato R (1964) The carbon monoxide binding pigment of liver microsomes. J Biol Chem 239:3137-3142.
    • (1964) J Biol Chem , vol.239 , pp. 3137-3142
    • Omura, T.1    Sato, R.2
  • 17
    • 0023065565 scopus 로고
    • Antineoplastic agent 124. Isolation, structure and synthesis of combretastatin-A1 and combretastatin-B1, potent new inhibitors of microtubule assembly, derived from Combretum caffrum
    • Pettit GR, Singh SB, Niven ML, Hamel E, and Schmidt JM (1987) Antineoplastic agent 124. Isolation, structure and synthesis of combretastatin-A1 and combretastatin-B1, potent new inhibitors of microtubule assembly, derived from Combretum caffrum. J Nat Prod 50:119-131.
    • (1987) J Nat Prod , vol.50 , pp. 119-131
    • Pettit, G.R.1    Singh, S.B.2    Niven, M.L.3    Hamel, E.4    Schmidt, J.M.5
  • 18
    • 0024513175 scopus 로고
    • Antineoplastic agent 145. Isolation and structure of the strong cell-growth and tubulin inhibitor combretastatin-A4
    • Pettit GR, Singh SB, Hamel E, Lin CM, Alberts DS, and Garciakendall D (1989) Antineoplastic agent 145. Isolation and structure of the strong cell-growth and tubulin inhibitor combretastatin-A4. Experientia 45:209-211.
    • (1989) Experientia , vol.45 , pp. 209-211
    • Pettit, G.R.1    Singh, S.B.2    Hamel, E.3    Lin, C.M.4    Alberts, D.S.5    Garciakendall, D.6
  • 21
    • 0642307227 scopus 로고    scopus 로고
    • Phase I trial of the antivascular agent combretastatin A-4 phosphate on a 5-day schedule to patients with cancer: Magnetic resonance imaging evidence for altered tumor blood flow
    • Stevenson JP, Rosen M, Sun W, Gallagher M, Haller DG, Vaughn D, Giantonio B, Zimmer R, Petros WP, Stratford M, et al. (2003) Phase I trial of the antivascular agent combretastatin A-4 phosphate on a 5-day schedule to patients with cancer: magnetic resonance imaging evidence for altered tumor blood flow. J Clin Oncol 21:4428-4438.
    • (2003) J Clin Oncol , vol.21 , pp. 4428-4438
    • Stevenson, J.P.1    Rosen, M.2    Sun, W.3    Gallagher, M.4    Haller, D.G.5    Vaughn, D.6    Giantonio, B.7    Zimmer, R.8    Petros, W.P.9    Stratford, M.10
  • 22
    • 0032929219 scopus 로고    scopus 로고
    • Determination of combretastatin A-4 and its phosphate ester pro-drug in plasma by high-performance liquid chromatography
    • Stratford MRL and Dennis ML (1999) Determination of combretastatin A-4 and its phosphate ester pro-drug in plasma by high-performance liquid chromatography. J Chromatogr B 721:77-85.
    • (1999) J Chromatogr B , vol.721 , pp. 77-85
    • Stratford, M.R.L.1    Dennis, M.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.