Using yeast models to probe the molecular basis of amyotrophic lateral sclerosis

Biochemical Society Transactions

Volumn 39, Issue 5, 2011, Pages 1481-1487

  Bastow, Emma L ^a   Gourlay, Campbell W ^a   Tuite, Mick F ^a  

^a UNIVERSITY OF KENT   (United Kingdom)

Author keywords

Amyotrophic lateral sclerosis (ALS); Fused in sarcoma (FUS); Mitochondrion; Protein aggregation; Saccharomyces cerevisiae; Superoxide dismutase 1 (SOD1); TAR DNA binding protein 43 (TDP 43)

Indexed keywords

ARIMOCLOMOL; BH3 PROTEIN; COPPER ZINC SUPEROXIDE DISMUTASE; FUSED IN SARCOMA PROTEIN; GLUCOSE; GLUTAREDOXIN; GLUTATHIONE; HEAT SHOCK PROTEIN 104; HYDROXYL RADICAL; IRON SULFUR PROTEIN; LYSINE; MANGANESE SUPEROXIDE DISMUTASE; MENADIONE; OXYGEN; PROTEIN; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; RILUZOLE; TAR DNA BINDING PROTEIN; UNCLASSIFIED DRUG; HEAT SHOCK PROTEIN 40; HEAT SHOCK TRANSCRIPTION FACTOR 1; HOMODIMER; HYDROGEN PEROXIDE; DNA BINDING PROTEIN; PROTEIN TDP-43; RNA BINDING PROTEIN; SUPEROXIDE DISMUTASE;

ALLELE; ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYOTROPHIC LATERAL SCLEROSIS; APOPTOSIS; AUXOTROPHY; BINDING SITE; BIOGENESIS; BIOLOGICAL MODEL; CELL FUNCTION; CELL PROTECTION; CONFERENCE PAPER; DISEASE ASSOCIATION; DISEASE COURSE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; ENZYME DEGRADATION; EUKARYOTE; FAMILIAL DISEASE; GAIN OF FUNCTION MUTATION; GENE DISRUPTION; GOLGI COMPLEX; HEAT SHOCK RESPONSE; HOST CELL; HUMAN; HUNTINGTON CHOREA; INTRACELLULAR SIGNALING; LOSS OF FUNCTION MUTATION; METABOLISM; METAL BINDING; MOLECULAR PROBE; NEUROPATHOLOGY; NONHUMAN; OXIDATION; OXIDATIVE STRESS; OXYGEN CONSUMPTION; OXYGEN TOXICITY; PARKINSON DISEASE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN HOMEOSTASIS; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION INITIATION; WILD TYPE; YEAST CELL; CYTOTOXICITY; DEGENERATIVE DISEASE; DISEASE MODEL; GENE INACTIVATION; GENETIC SCREENING; MITOCHONDRION; MOTONEURON; PROTEIN DEGRADATION; REVIEW; CHEMISTRY; GENETICS; MUTATION; PATHOPHYSIOLOGY; PHYSIOLOGY;

SACCHAROMYCES CEREVISIAE;

AMYOTROPHIC LATERAL SCLEROSIS; DNA-BINDING PROTEINS; HEAT-SHOCK RESPONSE; HUMANS; MUTATION; PROTEIN FOLDING; RNA-BINDING PROTEIN FUS; SACCHAROMYCES CEREVISIAE; SUPEROXIDE DISMUTASE;

EID: 80053349243     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST0391482     Document Type: Conference Paper

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