Neurotoxic 43-kDa TAR DNA-binding protein (TDP-43) triggers mitochondrion-dependent programmed cell death in yeast

Journal of Biological Chemistry

Volumn 286, Issue 22, 2011, Pages 19958-19972

  Braun, Ralf J ^a,b   Sommer, Cornelia ^a   Carmona Gutierrez, Didac ^a   Khoury, Chamel M ^a   Ring, Julia ^a   Büttner, Sabrina ^a   Madeo, Frank ^a  

^a UNIVERSITY OF GRAZ   (Austria)

^b UNIVERSITY OF BAYREUTH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; APOPTOSIS-INDUCING FACTORS; CASPASES; CELL LOSS; CYTOCHROME C; DELETERIOUS EFFECTS; DNA-BINDING PROTEIN; ENDONUCLEASES; MITOCHONDRIAL DNA; MOLECULAR MECHANISM; MOTOR NEURONS; PROGRAMMED CELL DEATHS; RESPIRATORY CHAINS;

CYTOTOXICITY; DISEASES; DNA; MITOCHONDRIA; NEURONS; OXIDATIVE STRESS; PROTEINS; TAR; YEAST;

CELL DEATH;

APOPTOSIS INDUCING FACTOR; CYTOCHROME C; ENDONUCLEASE G; INTERLEUKIN 1BETA CONVERTING ENZYME; MITOCHONDRIAL DNA; TAR DNA BINDING PROTEIN;

APOPTOSIS; ARTICLE; CELL DEATH; CELL MEMBRANE PERMEABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOTOXICITY; FUNGAL CELL; FUNGAL STRAIN; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RESPIRATORY CHAIN; SACCHAROMYCES CEREVISIAE;

CELL DEATH; DNA, FUNGAL; DNA, MITOCHONDRIAL; DNA-BINDING PROTEINS; HUMANS; MITOCHONDRIA; OXIDATIVE STRESS; OXYGEN CONSUMPTION; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; TDP-43 PROTEINOPATHIES;

EID: 79957583304     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.194852     Document Type: Article

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