Riluzole increases the amount of latent HSF1 for an amplified heat shock response and cytoprotection

PLoS ONE

Volumn 3, Issue 8, 2008, Pages

  Yang, Jingxian ^a   Bridges, Kristen ^a   Chen, Kuang Yu ^a   Liu, Alice Y C ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CHLOROQUINE; HEAT SHOCK PROTEIN; HEAT SHOCK TRANSCRIPTION FACTOR 1; MESSENGER RNA; RILUZOLE; AMINO ACID RECEPTOR STIMULATING AGENT; DNA BINDING PROTEIN; HEAT SHOCK TRANSCRIPTION FACTOR; LUCIFERASE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOPHAGY; CELL PROTECTION; CELL SURVIVAL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; EMBRYO; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE INDUCTION; HEAT SHOCK RESPONSE; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IMMUNOPRECIPITATION; KNOCKOUT GENE; NONHUMAN; OXIDATIVE STRESS; PROTEIN DEGRADATION; PROTEIN TARGETING; QUALITATIVE ANALYSIS; RAT; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; RNA INTERFERENCE; SPINAL CORD NERVE CELL; TRANSCRIPTION REGULATION; WESTERN BLOTTING; BIOSYNTHESIS; DEGENERATIVE DISEASE; DRUG EFFECT; GENETICS; HEAT; HELA CELL; NERVE CELL; PATHOPHYSIOLOGY; PHYSIOLOGY; PRENATAL DEVELOPMENT; SPINAL CORD;

CELL SURVIVAL; DNA-BINDING PROTEINS; EXCITATORY AMINO ACID AGONISTS; GENES, REPORTER; HELA CELLS; HOT TEMPERATURE; HUMANS; LUCIFERASES; NEURODEGENERATIVE DISEASES; NEURONS; RILUZOLE; SPINAL CORD; TRANSCRIPTION FACTORS;

EID: 50949128019     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0002864     Document Type: Article

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