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Volumn 312, Issue 1, 2011, Pages 117-127

Neuromedin B receptor antagonist suppresses tumor angiogenesis and tumor growth in vitro and in vivo

Author keywords

Angiogenesis; Breast cancer cells; Neuromedin B receptor antagonist; Tumor growth; Vascular endothelial cells

Indexed keywords

ANGIOGENESIS INHIBITOR; NEUROMEDIN B; PD 168368; UNCLASSIFIED DRUG;

EID: 80053304908     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2011.08.014     Document Type: Article
Times cited : (23)

References (43)
  • 1
    • 0036551292 scopus 로고    scopus 로고
    • Neuropeptides as growth factors for normal and cancerous cells
    • Rozengurt E. Neuropeptides as growth factors for normal and cancerous cells. Trends. Endocrinol. Metab. 2002, 13:128-134.
    • (2002) Trends. Endocrinol. Metab. , vol.13 , pp. 128-134
    • Rozengurt, E.1
  • 2
    • 0035952679 scopus 로고    scopus 로고
    • Autocrine and paracrine signaling through neuropeptide receptors in human cancer
    • Heasley L.E. Autocrine and paracrine signaling through neuropeptide receptors in human cancer. Oncogene 2001, 20:1563-1569.
    • (2001) Oncogene , vol.20 , pp. 1563-1569
    • Heasley, L.E.1
  • 3
    • 34548459014 scopus 로고    scopus 로고
    • Gastrin-releasing peptide receptor as a molecular target in experimental anticancer therapy
    • Cornelio D.B., Roesler R., Schwartsmann G. Gastrin-releasing peptide receptor as a molecular target in experimental anticancer therapy. Ann. Oncol. 2007, 18:1457-1466.
    • (2007) Ann. Oncol. , vol.18 , pp. 1457-1466
    • Cornelio, D.B.1    Roesler, R.2    Schwartsmann, G.3
  • 4
    • 0030614842 scopus 로고    scopus 로고
    • [D-Arg1, D-Trp5, 7, 9, Leu11]substance P: a novel potent inhibitor of signal transduction and growth in vitro and in vivo in small cell lung cancer cells
    • Seckl M.J., Higgins T., Widmer F., Rozengurt E. [D-Arg1, D-Trp5, 7, 9, Leu11]substance P: a novel potent inhibitor of signal transduction and growth in vitro and in vivo in small cell lung cancer cells. Cancer Res. 1997, 57:51-54.
    • (1997) Cancer Res. , vol.57 , pp. 51-54
    • Seckl, M.J.1    Higgins, T.2    Widmer, F.3    Rozengurt, E.4
  • 5
    • 21444441255 scopus 로고    scopus 로고
    • Development and function of bombesin-like peptides and their receptors
    • Ohki-Hamazaki H., Iwabuchi M., Maekawa F. Development and function of bombesin-like peptides and their receptors. Int. J. Dev. Biol. 2005, 49:293-300.
    • (2005) Int. J. Dev. Biol. , vol.49 , pp. 293-300
    • Ohki-Hamazaki, H.1    Iwabuchi, M.2    Maekawa, F.3
  • 6
    • 58849153281 scopus 로고    scopus 로고
    • Regulation and signaling of human bombesin receptors and their biological effects
    • Weber H.C. Regulation and signaling of human bombesin receptors and their biological effects. Curr. Opin. Endocrinol. Diabetes Obes. 2009, 16:66-71.
    • (2009) Curr. Opin. Endocrinol. Diabetes Obes. , vol.16 , pp. 66-71
    • Weber, H.C.1
  • 8
    • 38049132623 scopus 로고    scopus 로고
    • Bombesin-related peptides and their receptors: recent advances in their role in physiology and disease states
    • Gonzalez N., Moody T.W., Igarashi H., Ito T., Jensen R.T. Bombesin-related peptides and their receptors: recent advances in their role in physiology and disease states. Curr. Opin. Endocrinol. Diabetes Obes. 2008, 15:58-64.
    • (2008) Curr. Opin. Endocrinol. Diabetes Obes. , vol.15 , pp. 58-64
    • Gonzalez, N.1    Moody, T.W.2    Igarashi, H.3    Ito, T.4    Jensen, R.T.5
  • 9
    • 25444521559 scopus 로고    scopus 로고
    • Biologic relevance of mammalian bombesin-like peptides and their receptors in human malignancies
    • Qu X., Xiao D., Weber H.C. Biologic relevance of mammalian bombesin-like peptides and their receptors in human malignancies. Curr. Opin. Endocrinol. Diabetes 2003, 10:60-71.
    • (2003) Curr. Opin. Endocrinol. Diabetes , vol.10 , pp. 60-71
    • Qu, X.1    Xiao, D.2    Weber, H.C.3
  • 10
    • 0035051948 scopus 로고    scopus 로고
    • The case for gastrin-releasing peptide acting as a morphogen when it and its receptor are aberrantly expressed in cancer
    • Jensen J.A., Carroll R.E., Benya R.V. The case for gastrin-releasing peptide acting as a morphogen when it and its receptor are aberrantly expressed in cancer. Peptides 2001, 22:689-699.
    • (2001) Peptides , vol.22 , pp. 689-699
    • Jensen, J.A.1    Carroll, R.E.2    Benya, R.V.3
  • 11
    • 33846194960 scopus 로고    scopus 로고
    • Gastrin-releasing peptide mediates its morphogenic properties in human colon cancer by upregulating intracellular adhesion protein-1 (ICAM-1) via focal adhesion kinase
    • Taglia L., Matusiak D., Matkowskyj K.A., Benya R.V. Gastrin-releasing peptide mediates its morphogenic properties in human colon cancer by upregulating intracellular adhesion protein-1 (ICAM-1) via focal adhesion kinase. Am. J. Physiol. Gastrointest. Liver Physiol. 2007, 292:G182-190.
    • (2007) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.292
    • Taglia, L.1    Matusiak, D.2    Matkowskyj, K.A.3    Benya, R.V.4
  • 14
    • 21244505789 scopus 로고    scopus 로고
    • Gastrin-releasing peptide (GRP) induces angiogenesis and the specific GRP blocker 77427 inhibits tumor growth in vitro and in vivo
    • Martinez A., Zudaire E., Julian M., Moody T.W., Cuttitta F. Gastrin-releasing peptide (GRP) induces angiogenesis and the specific GRP blocker 77427 inhibits tumor growth in vitro and in vivo. Oncogene 2005, 24:4106-4113.
    • (2005) Oncogene , vol.24 , pp. 4106-4113
    • Martinez, A.1    Zudaire, E.2    Julian, M.3    Moody, T.W.4    Cuttitta, F.5
  • 16
    • 0029155830 scopus 로고
    • Neuromedin B stimulates arachidonic acid release, c-fos gene expression, and the growth of C6 glioma cells
    • Moody T.W., Fagarasan M., Zia F. Neuromedin B stimulates arachidonic acid release, c-fos gene expression, and the growth of C6 glioma cells. Peptides 1995, 16:1133-1140.
    • (1995) Peptides , vol.16 , pp. 1133-1140
    • Moody, T.W.1    Fagarasan, M.2    Zia, F.3
  • 18
    • 70350617693 scopus 로고    scopus 로고
    • Neuromedin B induces angiogenesis via activation of ERK and akt in endothelial cells
    • Park H.J., Kim S.R., Bae S.K., et al. Neuromedin B induces angiogenesis via activation of ERK and akt in endothelial cells. Exp. Cell Res. 2009, 315:3359-3369.
    • (2009) Exp. Cell Res. , vol.315 , pp. 3359-3369
    • Park, H.J.1    Kim, S.R.2    Bae, S.K.3
  • 19
    • 77953555625 scopus 로고    scopus 로고
    • Targeting gastrin releasing peptide receptors: new options for the therapy and diagnosis of cancer
    • Hohla F., Schally A.V. Targeting gastrin releasing peptide receptors: new options for the therapy and diagnosis of cancer. Cell Cycle. 2010, 9:1738-1741.
    • (2010) Cell Cycle. , vol.9 , pp. 1738-1741
    • Hohla, F.1    Schally, A.V.2
  • 20
    • 9344246896 scopus 로고    scopus 로고
    • Targeting gastrin-releasing peptide receptors for cancer treatment
    • Zhou J., Chen J., Mokotoff M., Ball E.D. Targeting gastrin-releasing peptide receptors for cancer treatment. Anticancer Drugs 2004, 15:921-927.
    • (2004) Anticancer Drugs , vol.15 , pp. 921-927
    • Zhou, J.1    Chen, J.2    Mokotoff, M.3    Ball, E.D.4
  • 22
    • 51349137154 scopus 로고    scopus 로고
    • Gastrin-releasing peptide receptor silencing suppresses the tumorigenesis and metastatic potential of neuroblastoma
    • Qiao J., Kang J., Ishola T.A., Rychahou P.G., Evers B.M., Chung D.H. Gastrin-releasing peptide receptor silencing suppresses the tumorigenesis and metastatic potential of neuroblastoma. Proc. Natl. Acad. Sci. USA 2008, 105:12891-12896.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 12891-12896
    • Qiao, J.1    Kang, J.2    Ishola, T.A.3    Rychahou, P.G.4    Evers, B.M.5    Chung, D.H.6
  • 23
    • 0015822275 scopus 로고
    • Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria
    • Jaffe E.A., Nachman R.L., Becker C.G., Minick C.R. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J. Clin. Invest. 1973, 52:2745-2756.
    • (1973) J. Clin. Invest. , vol.52 , pp. 2745-2756
    • Jaffe, E.A.1    Nachman, R.L.2    Becker, C.G.3    Minick, C.R.4
  • 24
    • 67650632787 scopus 로고    scopus 로고
    • Characterization of putative GRP- and NMB-receptor antagonist's interaction with human receptors
    • Gonzalez N., Mantey S.A., Pradhan T.K., Sancho V., Moody T.W., Coy D.H., Jensen R.T. Characterization of putative GRP- and NMB-receptor antagonist's interaction with human receptors. Peptides 2009, 30:1473-1486.
    • (2009) Peptides , vol.30 , pp. 1473-1486
    • Gonzalez, N.1    Mantey, S.A.2    Pradhan, T.K.3    Sancho, V.4    Moody, T.W.5    Coy, D.H.6    Jensen, R.T.7
  • 25
    • 0025006482 scopus 로고
    • Characterization, in some human breast cancer cell lines, of gastrin-releasing peptide-like receptors which are absent in normal breast epithelial cells
    • Giacchetti S., Gauville C., de Cremoux P., Bertin L., Berthon P., Abita J.P., Cuttitta F., Calvo F. Characterization, in some human breast cancer cell lines, of gastrin-releasing peptide-like receptors which are absent in normal breast epithelial cells. Int. J. Cancer 1990, 46:293-298.
    • (1990) Int. J. Cancer , vol.46 , pp. 293-298
    • Giacchetti, S.1    Gauville, C.2    de Cremoux, P.3    Bertin, L.4    Berthon, P.5    Abita, J.P.6    Cuttitta, F.7    Calvo, F.8
  • 26
    • 0026802370 scopus 로고
    • Stimulation by bombesin and inhibition by bombesin/gastrin-releasing peptide antagonist RC-3095 of growth of human breast cancer cell lines
    • Yano T., Pinski J., Groot K., Schally A.V. Stimulation by bombesin and inhibition by bombesin/gastrin-releasing peptide antagonist RC-3095 of growth of human breast cancer cell lines. Cancer Res. 1992, 52:4545-4547.
    • (1992) Cancer Res. , vol.52 , pp. 4545-4547
    • Yano, T.1    Pinski, J.2    Groot, K.3    Schally, A.V.4
  • 27
    • 0030014619 scopus 로고    scopus 로고
    • Bombesin specifically induces intracellular calcium mobilization via gastrin-releasing peptide receptors in human prostate cancer cells
    • Aprikian A.G., Han K., Chevalier S., Bazinet M., Viallet J. Bombesin specifically induces intracellular calcium mobilization via gastrin-releasing peptide receptors in human prostate cancer cells. J. Mol. Endocrinol. 1996, 16:297-306.
    • (1996) J. Mol. Endocrinol. , vol.16 , pp. 297-306
    • Aprikian, A.G.1    Han, K.2    Chevalier, S.3    Bazinet, M.4    Viallet, J.5
  • 28
    • 41149176081 scopus 로고    scopus 로고
    • International union of pharmacology. LXVIII. Mammalian bombesin receptors: nomenclature, distribution, pharmacology, signaling, and functions in normal and disease states
    • Jensen R.T., Battey J.F., Spindel E.R., Benya R.V. International union of pharmacology. LXVIII. Mammalian bombesin receptors: nomenclature, distribution, pharmacology, signaling, and functions in normal and disease states. Pharmacol. Rev. 2008, 60:1-42.
    • (2008) Pharmacol. Rev. , vol.60 , pp. 1-42
    • Jensen, R.T.1    Battey, J.F.2    Spindel, E.R.3    Benya, R.V.4
  • 29
    • 0024400745 scopus 로고
    • Discovery, isolation, and characterization of bombesin-like peptides
    • Erspamer V. Discovery, isolation, and characterization of bombesin-like peptides. Ann. NY Acad. Sci. 1988, 547:3-9.
    • (1988) Ann. NY Acad. Sci. , vol.547 , pp. 3-9
    • Erspamer, V.1
  • 30
    • 0020558866 scopus 로고
    • Neuromedin B: a novel bombesin-like peptide identified in porcine spinal cord
    • Minamino N., Kangawa K., Matsuo H. Neuromedin B: a novel bombesin-like peptide identified in porcine spinal cord. Biochem. Biophys. Res. Commun. 1983, 114:541-548.
    • (1983) Biochem. Biophys. Res. Commun. , vol.114 , pp. 541-548
    • Minamino, N.1    Kangawa, K.2    Matsuo, H.3
  • 31
    • 68649095592 scopus 로고    scopus 로고
    • Gastrin-releasing peptide receptor in breast cancer mediates cellular migration and interleukin-8 expression
    • Chao C., Ives K., Hellmich H.L., Townsend C.M., Hellmich M.R. Gastrin-releasing peptide receptor in breast cancer mediates cellular migration and interleukin-8 expression. J. Surg. Res. 2009, 156:26-31.
    • (2009) J. Surg. Res. , vol.156 , pp. 26-31
    • Chao, C.1    Ives, K.2    Hellmich, H.L.3    Townsend, C.M.4    Hellmich, M.R.5
  • 32
    • 0032804044 scopus 로고    scopus 로고
    • Gastrin-releasing peptide receptors in non-neoplastic and neoplastic human breast
    • Gugger M., Reubi J.C. Gastrin-releasing peptide receptors in non-neoplastic and neoplastic human breast. Am. J. Pathol. 1999, 155:2067-2076.
    • (1999) Am. J. Pathol. , vol.155 , pp. 2067-2076
    • Gugger, M.1    Reubi, J.C.2
  • 33
    • 0032055880 scopus 로고    scopus 로고
    • Inhibition of growth of MDA-MB-231 human breast cancer xenografts in nude mice by bombesin/gastrin-releasing peptide (GRP) antagonists RC-3940-II and RC-3095
    • Miyazaki M., Lamharzi N., Schally A.V., Halmos G., Szepeshazi K., Groot K., Cai R.Z. Inhibition of growth of MDA-MB-231 human breast cancer xenografts in nude mice by bombesin/gastrin-releasing peptide (GRP) antagonists RC-3940-II and RC-3095. Eur. J. Cancer 1998, 34:710-717.
    • (1998) Eur. J. Cancer , vol.34 , pp. 710-717
    • Miyazaki, M.1    Lamharzi, N.2    Schally, A.V.3    Halmos, G.4    Szepeshazi, K.5    Groot, K.6    Cai, R.Z.7
  • 34
    • 0037133576 scopus 로고    scopus 로고
    • Bombesin antagonists inhibit growth of MDA-MB-435 estrogen-independent breast cancers and decrease the expression of the ErbB-2/HER-2 oncoprotein and c-jun and c-fos oncogenes
    • Bajo A.M., Schally A.V., Krupa M., Hebert F., Groot K., Szepeshazi K. Bombesin antagonists inhibit growth of MDA-MB-435 estrogen-independent breast cancers and decrease the expression of the ErbB-2/HER-2 oncoprotein and c-jun and c-fos oncogenes. Proc. Natl. Acad. Sci. USA 2002, 99:3836-3841.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 3836-3841
    • Bajo, A.M.1    Schally, A.V.2    Krupa, M.3    Hebert, F.4    Groot, K.5    Szepeshazi, K.6
  • 35
    • 0034624267 scopus 로고    scopus 로고
    • Nonpeptide neuromedin B receptor antagonists inhibit the proliferation of C6 cells
    • Moody T.W., Jensen R.T., Garcia L., Leyton J. Nonpeptide neuromedin B receptor antagonists inhibit the proliferation of C6 cells. Eur. J. Pharmacol. 2000, 409:133-142.
    • (2000) Eur. J. Pharmacol. , vol.409 , pp. 133-142
    • Moody, T.W.1    Jensen, R.T.2    Garcia, L.3    Leyton, J.4
  • 37
    • 0030919922 scopus 로고    scopus 로고
    • Bombesin and neuromedin B stimulate the activation of p42(mapk) and p74(raf-1) via a protein kinase C-independent pathway in rat-1 cells
    • Charlesworth A., Rozengurt E. Bombesin and neuromedin B stimulate the activation of p42(mapk) and p74(raf-1) via a protein kinase C-independent pathway in rat-1 cells. Oncogene 1997, 14:2323-2329.
    • (1997) Oncogene , vol.14 , pp. 2323-2329
    • Charlesworth, A.1    Rozengurt, E.2
  • 38
    • 78951489049 scopus 로고    scopus 로고
    • Feedback regulation of EGFR signalling: Decision making by early and delayed loops
    • Avraham R., Yarden Y. Feedback regulation of EGFR signalling: Decision making by early and delayed loops. Nat. Rev. Mol. Cell Biol. 2011, 12:104-117.
    • (2011) Nat. Rev. Mol. Cell Biol. , vol.12 , pp. 104-117
    • Avraham, R.1    Yarden, Y.2
  • 40
    • 33645217263 scopus 로고    scopus 로고
    • EGFR signaling pathway in breast cancers: from traditional signal transduction to direct nuclear translocalization
    • Lo H.W., Hsu S.C., Hung M.C. EGFR signaling pathway in breast cancers: from traditional signal transduction to direct nuclear translocalization. Breast Cancer Res. Treat. 2006, 95:211-218.
    • (2006) Breast Cancer Res. Treat. , vol.95 , pp. 211-218
    • Lo, H.W.1    Hsu, S.C.2    Hung, M.C.3
  • 41
    • 33745213627 scopus 로고    scopus 로고
    • AMPK and cell proliferation - AMPK as a therapeutic target for atherosclerosis and cancer
    • Motoshima H., Goldstein B.J., Igata M., Araki E. AMPK and cell proliferation - AMPK as a therapeutic target for atherosclerosis and cancer. J. Physiol. 2006, 574:63-71.
    • (2006) J. Physiol. , vol.574 , pp. 63-71
    • Motoshima, H.1    Goldstein, B.J.2    Igata, M.3    Araki, E.4
  • 42
    • 28244466264 scopus 로고    scopus 로고
    • 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase
    • Rattan R., Giri S., Singh A.K., Singh I. 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase. J. Biol. Chem. 2005, 280:39582-39593.
    • (2005) J. Biol. Chem. , vol.280 , pp. 39582-39593
    • Rattan, R.1    Giri, S.2    Singh, A.K.3    Singh, I.4
  • 43
    • 37549005069 scopus 로고    scopus 로고
    • Implication of AMP-activated protein kinase and akt-regulated survivin in lung cancer chemopreventive activities of deguelin
    • Jin Q., Feng L., Behrens C., Bekele B.N., Wistuba I.I., Hong W.K., Lee H.Y. Implication of AMP-activated protein kinase and akt-regulated survivin in lung cancer chemopreventive activities of deguelin. Cancer Res. 2007, 67:11630-11639.
    • (2007) Cancer Res. , vol.67 , pp. 11630-11639
    • Jin, Q.1    Feng, L.2    Behrens, C.3    Bekele, B.N.4    Wistuba, I.I.5    Hong, W.K.6    Lee, H.Y.7


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