Cathepsins B1 and B2 of trichobilharzia SPP., bird schistosomes causing cercarial dermatitis

Advances in Experimental Medicine and Biology

Volumn 712, Issue , 2011, Pages 136-154

  Kašný, Martin ^a   Mikeš, Libor ^a   Dolečková, Kateřina ^a   Hampl, Vladimír ^a   Dvořák, Jan ^b   Novotný, Marian ^a   Horák, Petr ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

^b INSTITUTE OF PARASITOLOGY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN B; CATHEPSIN X; PEPTIDASE; CATHEPSIN;

ARTICLE; CATHEPSIN B1 GENE; CATHEPSIN B2 GENE; CERCARIAL DERMATITIS; DERMATITIS; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME MECHANISM; ENZYME SPECIFICITY; GENE; GENE EXPRESSION REGULATION; HOST PARASITE INTERACTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCHISTOSOMA JAPONICUM; SCHISTOSOMA MANSONI; SEQUENCE ANALYSIS; TREMATODE; TREMATODIASIS; TRICHOBILHARZIA REGENTI; TRICHOBILHARZIA SZIDATI; AMINO ACID SEQUENCE; ANIMAL; BIRD; BIRD DISEASE; CERCARIA; CHEMISTRY; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; PARASITOLOGY; REVIEW; SCHISTOSOMA;

AMINO ACID SEQUENCE; ANIMALS; BIRD DISEASES; BIRDS; CATHEPSINS; CERCARIA; HUMANS; MOLECULAR SEQUENCE DATA; SCHISTOSOMA;

EID: 80053299827     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4419-8414-2_9     Document Type: Article

References (81)

1. Dubois JP, Buet A, Cusin I et al. Epidemiological studies related to cercarial dermatitis in lakes of the Savoy District (France). Helminthologia 2001; 38:244
2. Thors C, Linder E. Swimmer's itch in Sweden. Helminthologia 2001; 38:244
3. Mas-Coma S, Valero MA, Bargues MD. Climate change effects on trematodiases, with emphasis on zoonotic fascioliasis and schistosomiasis. Vet Parasitol 2009; 163:264-280
4. Larsen AH, Bresciani J, Buchmann K. Increasing frequency of cercarial dermatitis in higher latitudes. Acta Parasitol 2004; 49:217-221
5. Skirnisson K, Aldhoun JA, Kolarova L. A review on swimmers itch and the occurrence of bird schistosomes in Iceland. J Helminthol 2009; 83:165-171
6. Davis NE. A survey of waterfowl for echinostomes and schistosomes from Lake Wanaka and the Waitaki River watershed. N Z J Helminthol 2006; 80:33-40
7. Brant SV, Loker ES. Molecular systematics of the avian schistosome genus Trichobilharzia (Trematoda: Schistosomatidae) in North America. J Parasitol 2009; 95:941-963
8. Horak P, Kolarova L, Adema C. Biology ofthe schistosome genus Trichobilharzia. Adv Parasitol 2002; 52:155-233
9. Horak P, Dvorak J, Kolarova Letal. Trichobilharzia regenti, a pathogen ofthe avian and mammalian central nervous system. Parasitology 1999; 119:577-581
10. Horak P, Mikes L, Rudolfova J et al. Penetration of Trichobilharzia cercariae into mammals: dangerous or negligible event? Parasite 2008; 15:299-303
11. De Jong-Brink M, Bergamin-Sassen M, Solis SM. Multiple strategies of schistosomes to meet their requirements in the intermediate host. Parasitology 2002; 123:S129-S141
12. Haas W. Parasitic worms: strategies of host finding, recognition and invasion. Zoology 2003; 34:927-934
13. Hertel J, Holweg A, Haberl B et al. Snail odour-clouds: spreading and contribution to the transmission success of Trichobilharzia ocellata (Trematoda, Digenea) miracidia. Oecologia 2006; 147:173-180
14. Dvorak J, Delcroix M, Rossi A et al. Multiple cathepsin B isoforms in schistosomula of Trichobilharzia regenti: identification, characterization and putative role in migration and nutrition. Int J Parasitol 2005; 35:895-910
15. Mikes L, Zidkova L, Kasny M et al. In vitro stimulation of penetration gland emptying by Trichobilharzia szidati and T. regenti (Schistosomatidae) cercariae. Quantitative collection and partial characterization of the products. Parasitol Res 2005; 96:230-241
16. Kasny M, Mikes L, Dalton JP et al. Comparison of cysteine peptidase activities in Trichobilharzia regenti and Schistosoma mansoni cercariae. Parasitology 2007; 134:1599-1609
17. DoleckovaK, Kasny M, Mikes L et al. The functional expression and characterization of a cysteine peptidase from the invasive stage of the neuropathogenic schistosome Trichobilharzia regenti. Int J Parasitol 2009; 39:201-211
18. Kasny M, Mikes L, Hampl V et al. Peptidases of trematodes. Adv Parasitol 2009; 69:205-297
19. Bahgat M and Ruppel A. Biochemical comparison of the serine protease (elastase) activities in cercarial secretions from Trichobilharzia ocellata and Schistosoma mansoni. Parasitol Res 2002; 88:495-500
20. Dalton JP, Clough KA, Jones MK et al. Characterization of the cathepsin-like cysteine proteinases of Schistosoma mansoni. Infect Immun 1996; 64:1328-1334
21. Dalton JP, Clough KA, Jones MK et al. The cysteine proteinases of Schistosoma mansoni cercariae. Parasitology 1997; 114;105-112
22. Dvorak J, Mashiyama ST, Braschi S et al. Differential use of protease families for invasion by schistosome cercariae. Biochimie 2008; 90:345-348
23. Kourilova P, Hogg KG, Kolarova L et al. Cercarial dermatitis caused by bird schistosomes comprises both immediate and late phase cutaneous hypersensitivity reactions. J Immunol 2004; 172:3766-3774
24. Lichtenbergova L, Kolbekova P, Kourilova P et al. Antibody responses induced by Trichobilharzia regenti antigens in murine and human hosts exhibiting cercarial dermatitis. Parasite Immunol 2008; 30:585-595
25. Doleckova K, Kasny M, Mikes L et al. Peptidases of Trichobilharzia regenti (Schistosomatidae) and its molluscan host Radix peregra s. lat. (Lymnaeidae): construction and screening of cDNA library from intramolluscan stages of the parasite. Folia Parasitol 2007; 54:94-98
26. Rawlings ND, Morton FR, Kok CY et al. MEROPS: the peptidase database. Nucleic Acids Res 2008; 36:320-325
27. Sajid M., McKerrow JH. Cysteine proteases ofparasitic organisms. Mol Biochem Parasitol 2002; 120:1-21
28. McKerrow JH, Caffrey C, Kelly B et al. Proteases in Parasitic Diseases Annu Rev Pathog Mech Dis 2006; 1:497-536
29. Caffrey CR, Rheinberg CE, Mone H et al. Schistosomajaponicum, S mansoni, S haematobium, S intercalatum and S rodhaini: cysteine-class cathepsin activities in the vomitus of adult worms. Parasitol Res 1997; 83:37-41
30. Caffrey CR, Ruppel A. Affinity isolation and characterization ofthe cathepsin B-like proteinase Sj31 from Schistosoma japonicum. The J Parasitol 1997a; 82:1112-1118
31. Caffrey CR, Ruppel A. Cathepsin B-like activity predominates over cathepsin L-like activity in adult Schistosoma mansoni and S. japonicum. Parasitol Res 1997b; 83:632-635
32. Sajid M, McKerrow JH, Hansell E et al. Functional expression and characterization of Schistosoma mansoni cathepsin B and its trans-activation by an endogenous asparaginyl endopeptidase. Mol Biochem Parasitol 2003; 131:65-75
33. Caffrey CR, McKerrow JH, Salter JP et al. Blood 'n' guts: an update on schistosome digestive peptidases. Trends Parasitol 2004; 20:241-248
34. Delcroix M, Sajid M, Caffrey CR et al. A multienzyme network functions in intestinal protein digestion by a platyhelminth parasite. J Biol Chem 2006; 282:39316-39329
35. Delcroix M, Medzihradsky K, Caffrey CR et al. Proteomic analysis of adult S. mansoni gut contents. Mol Biochem Parasitol 2007; 154:95-97
36. Doleckova K, Albrecht T, Mikes L et al. Cathepsins B1 and B2 in the neuropathogenic schistosome Trichobilharzia regenti: distinct expression and presumptive role throughout the life cycle. Parasitol Res 2010; 107:751-755
37. Jacobsen W, Cristians U, Benet L. In vitro evaluation ofthe disposition of a novel cysteine protease inhibitor. Drug Metab Dispos 2000; 28:1343-1351
38. Xiao SH. Development of antischistosomal drugs in China, with particular consideration to praziquantel and the artemisinins. Acta Trop 2005; 96:153-167
39. Renslo AR, McKerrow JH. Drug discovery and development for neglected parasitic diseases. Nat Chem Biol 2006; 12:701-710
40. Abdulla MH, Lim KCh, Sajid M et al. Schistosomiasis mansoni: Novel chemotherapy using a cysteine protease inhibitor. PLoS Med 2007; 4:130-138
41. Musil D, Zucic D, Turk D et al. The refined 2.15 A X-ray crystal structure ofhuman liver cathepsin B: the structural basis for its specificity. EMBO J1991; 10:2321-2330
42. Turk B, Turk D, Turk V. Lysosomal cysteine proteases: more than scavengers. Biochim Biophys Acta 2000; 147:98-111
43. Caffrey CR, Salter JP, Lucas KD et al. SmCB2, a novel tegumental cathepsin B from adult Schistosoma mansoni. Mol Biochem Parasitol 2002; 121:49-61
44. Lecaille F, Kaleta J, Brome D. Human and parasitic papain-like cysteine proteases: Their role in physiology and pathology and recent developments in inhibitor design. Chem Rev 2002; 102:4459-4488
45. Rawlings ND, Barrett AJ. Introduction: the clans and families of cysteine peptidases. In Handbook of Proteolytic Enzymes, 2 edn (Barrett, A.J., Rawlings, N.D. and Woessner, J.F. eds), Elsevier, Amsterdam 2004, 1051-1071
46. Merckelbach A, Hasse S, Dell R et al. cDNA sequences of Schistosoma japonicum coding for two cathepsin B-like proteins and Sj32. Ann Trop Med Parasitol 1994; 45:193-198
47. Caffrey CR, Mathieu MA, Gaffney AM et al. Identification of a cDNA encoding an active asparaginyl endopeptidase ofSchistosoma mansoni and its expression in Pichia pastoris. FEBS Lett 2000; 466:244-248
48. Berriman M, Haas BJ, LoVerde PT et al. The genome ofthe blood fluke Schistosoma mansoni. Nature 2009; 460:352-358
49. Pils B, Schultz J. 2004. Inactive enzyme-homologues find new function in regulatory processes. Mol Biochem Parasitol 2004; 340:399-404
50. Atkinson HJ, Babbitt PC, Sajid M. The global cysteine peptidase landscape in parasites. Trends Parasitol 2009; 12:573-581
51. Law RH, Smooker PM, Irving JA et al. Cloning and expression of the major secreted cathepsin B-like protein fromjuvenile Fasciola hepatica and analysis of immunogenicity following liver fluke infection. Infect Immun 2003; 71:6921-6932
52. Meemon K, Grams R, Vichasri GS et al. Molecular cloning and analysis of stage and tissue-specific expression ofcathepsin B encoding genes from Fasciola gigantica. Mol Biochem Parasitol 2004; 136;1-10
53. Beckham S, Law RHP, Smooker PM et al. Production and processing of a recombinant Fasciola hepatica cathepsin B-like enzyme (FhcatB1) reveals potential processing mechanisms in the parasite. Biol Chem 2006; 387:1053-1061
54. Illy Ch, Quraishi O, Wang J et al. Role of the occluding loop in cathepsin B activity. J Biol Chem 1997; 10:1197-1202
55. Krupa JC, Hasnain S, Nagler DK et al. S2'substrate specificity and the role ofHis110 and His111 in activity of human cathepsin B. Biochem J 2002; 361:613-619
56. Nagler DK, Storer AC, Portaro FC et al. Major increase in endopeptidase activity of human cathepsin B upon removal of occluding loop contacts. Biochemistry 1997; 41:12608-12615
57. Quraishi O, Nagler DK, Fox T et al. The occluding loop in cathepsin B defines the pH dependence of inhibition by its propeptide. Biochemistry 1999; 38:5017-5023
58. Berti PJ, Storer AC. Alignment/phylogeny of the papain superfamily of cysteine proteases. J Mol Biol 1995; 246:273-283
59. Jolly ER, Chin ChS, Miller S et al. Gene expression patterns during adaptation of a helminth parasite to different environmental niches. Genome Biol 2007; 8:R65
60. Liu F, Lu J, Hu W et al. New perspectives on host-parasite interplay by comparative transcriptomic and proteomic analyses of Schistosoma japonicum. PLoS Pathog 2006; 2:268-281
61. Choe Y, Leonetti F, Greenbaum DC et al. Substrate profiling ofcysteine proteases using a combinatorial peptide library identifies functionally unique specificities. J Biol Chem 2006; 281:12824-12832
62. Greenbaum D, Medzihradszky KF, Burlingame A et al. Epoxide electrophiles as activity-dependent cysteine protease profiling and discovery tools. Chem Biol 2000; 7:569-581
63. Dvorak J, Mashiyama ST, Braschi S et al. Differential use of protease families for invasion by schistosome cercariae. Biochimie 2008; 90:345-348
64. Spiess E, Bruning A, Gack S et al. Cathepsin B activity in human lung tumor cell lines: ultrastructural localization, pH sensitivity and inhibitor status at the cellular level. The J Histochem Cytochem 1994; 42:917-929
65. Khersonsky O, RoodveldtC, TawfikDS. Enzyme promiscuity: evolutionary and mechanistic aspects. Curr Opin Chem Biol 2006; 10:498-508
66. Rudolfova J, Hampl V, Bayssade-Dufour C et al. Validity reassessment of Trichobilharzia species using Lymnaea stagnalis as the intermediate host. Parasitol Res 2005; 95:79-89
67. Salter JP, Lim KC, Hansell E et al. Schistosome invasion of human skin and degradation of dermal elastin are mediated by a single serine protease. J Biol Chem 2000; 275:38667-38673
68. Salter JP, Choe Y, Albrecht H et al. Cercarial elastase is encoded by a functionally conserved gene family across multiple species of schistosomes J Biol Chem 2002; 277:24618-24624
69. Baig S, Damian RT, Peterson DS. A novel cathepsin B active site motif is shared by helminth bloodfeeders Exp Parasitol 2002; 101:83-89
70. Chanova M, Horak P. Terminal phase of bird schistosomiasis caused by Trichobilharzia regenti (Schistosomatidae) in ducks (Anas platyrhynchos f. domestica). Folia Parasitol 2007; 54:105-107
71. Sojka D, Hajdusek O, Dvorak J et al. IrAE-An asparaginyl endopeptidase (legumain) in the gut ofthe hard tick Ixodes ricinus. Int J Parasitol 2007; 37:713-724
72. Krautz-Peterson G, Skelly PJ. Schistosome asparaginyl endopeptidase (legumain) is not essential for cathepsin B1 activation in vivo. Mol Biochem Parasitol 2008; 159:54-58
73. Dalton JP, Brindley PJ, Donnelly S et al. The enigmatic asparaginyl endopeptidase of helminth parasites. Trends Parasitol 2009; 25:59-61
74. Mathieu MA, Bogyo M, Caffrey CR et al. Substrate specificity of schistosome versus human legumain determined by P1-P3 peptide libraries. Mol Biochem Parasitol 2002; 121:99-105
75. WulffC, Haeberlein S, Haas W. Cream formulations protecting against cercarial dermatitis by Trichobilharzia. Parasitol Res 2007; 101:98-111
76. Stamatakis A. RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models. Bioinformatics 2005; 22:2688-2690
77. Benson DA, Karsch-Mizrachi I, Lipman DJ et al. GenBank. Nucleic Acids Res 2009; 37:D26-31
78. Sali A, Blundell TL. Comparative protein modelling by satisfaction of spatial restraints. J Mol Biol 1993; 246:273-283
79. Podobnik M, Kuhelj R, Turk V et al. Crystal structure of the wild-type human procathepsin B at 2.5 A resolution reveals the native active site of a papain-like cysteine protease zymogen. J Mol Biol 1993; 271:774-788
80. Stern I, Schaschke N, Moroder L et al. Crystal structure of NS-134 in complex with bovine cathepsin B: a two-headed epoxysuccinyl inhibitor extends along the elntire active-site cleft. Biochem J 2004; 381:511-517
81. Schneidman-Duhovny D, Inbar Y, Nussinov R et al. PatchDock and SymmDock: servers for rigid and symmetric docking. Nucleic Acids Res 2005; 3:363-367.