Major increase in endopeptidase activity of human cathepsin B upon removal of occluding loop contacts

Biochemistry

Volumn 36, Issue 41, 1997, Pages 12608-12615

  Nägler, Dorit K ^a   Storer, Andrew C ^a   Portaro, Fernanda C V ^b   Carmona, Euridice ^b   Juliano, Luiz ^c   Ménard, Robert ^a  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^b INSTITUTO BUTANTAN   (Brazil)

^c FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; ASPARTIC ACID; CATHEPSIN B; CATHEPSIN L; CYSTEINE PROTEINASE; HISTIDINE; PAPAIN;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SUBSTRATE; HUMAN; PH; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

CATHEPSIN B; ENDOPEPTIDASES; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; MUTATION; PROTEIN CONFORMATION;

FELIS CATUS;

EID: 0040084898     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi971264+     Document Type: Article

References (32)

1. Barrett, A. J. (1980) Biochem. J. 187, 909-912.
2. Barrett, A. J., & Kirschke, H. (1981) Methods Enzymol. 80, 535-561.
3. Barrett, A. J., Kembhavi, A. A., Brown, M. A., Kirschke, H., Knight, C. G., Tamai, M., & Hanada, K. (1982) Biochem. J. 201, 189-198.
4. Carmona, E., Dufour, E., Plouffe, C., Takebe, S., Mason, P., Mort, J. S., & Ménard, R. (1996) Biochemistry 35, 8149-8157.
5. Chagas, J. R., Juliano, L., & Prado, E. S. (1991) Anal. Biochem. 192, 419-425.
6. Cygler, M., Sivaraman, J., Grochulski, P., Coulombe, R., Storer, A. C., & Mort, J. S. (1996) Structure 4, 405-416.
7. Fox, T., deMiguel, E., Mort, J. S., & Storer, A. C. (1992) Biochemistry 31, 12571-12576.
8. Fox, T., Mason, P., Storer, A. C., & Mort, J. S. (1995) Protein Eng. 8, 53-57.
9. Hasnain, S., Huber, C. P., Muir, A., Rowan, A. D., & Mort, J. S. (1992) Biol. Chem. Hoppe-Seyler 373, 413-418.
10. Hasnain, S., Hirama, T., Huber, C. P., Mason, P., & Mort, J. S. (1993) J. Biol. Chem. 268, 235-240.
11. Hirata, I. Y., Cezari, M. H. S., Nakaie, C. R., Boschcov, P., Ito, A. S., Juliano, M. A., & Juliano, L. (1994) Lett. Pept. Sci. 1, 299-308.
12. Illy C., Quraishi, O., Wang, J., Purisima, E., Vernet, T., & Mort, J. (1997) J. Biol. Chem. 272, 1197-1202.
13. Jia, Z., Hasnain, S., Hirama, T., Lee, X., Mort, J. S., To, R., & Huber, C. P. (1995) J. Biol. Chem. 270, 5527-5533.
14. Khouri, H. E., Plouffe, C., Hasnain, S., Hirama, T., Storer, A. C., & Ménard, R. (1991a) Biochem. J. 275, 751-757.
15. Khouri, H. E., Vernet, T., Ménard, R., Parlati, F., Laflamme, P., Tessier, D. C., Gour-Salin, B., Thomas, D. Y., & Storer, A. C. (1991b) Biochemistry 30, 8929-8936.
16. Kirschke, H., & Barrett, A. J. (1987) in Lysosomes: their role in protein breakdown (Glaumann, H., & Ballard, F. J., Eds.) pp 193-238, Academic Press, London.
17. Lalmanach, G., Serveau, C., Brillard-Bourdet, M., Chagas, J. R., Mayer, R., Juliano, L., & Gauthier, F. (1995) J. Protein Chem. 14, 645-653.
18. Mach, L., Stüwe, K., Hagen, A., Ballaun, C., & Glössl, J. (1992) Biochem. J. 282, 577-582.
19. Mach, L., Schwihla, H., Stuwe, K., Rowan, A. D., Mort, J. S., & Glössl, J. (1993) Biochem, J. 293, 437-442.
20. Mach, L., Mort, J. S., & Glössl, J. (1994) J. Biol. Chem. 269, 13036-13040.
21. Ménard, R., Khouri, H. E., Plouffe, C., Dupras, R., Ripoll, D., Vernet, T., Tessier, D. C., Laliberté, F., Thomas, D. Y., & Storer, A. C. (1990) Biochemistry 29, 6706-6713.
22. Mort, J. S., Recklies, A. D., & Poole, A. R. (1984) Arthritis Rheum. 27, 509-515.
23. Musil, D., Zucic, D., Turk, D., Engh, R. A., Mayr, I., Huber, R., Popovic, T., Turk, V., Towatari, T., Katunuma, N., & Bode, W. (1991) EMBO J. 10, 2321-2330.
24. Schechter, I., & Berger, A. (1967) Biochem. Biophys. Res. Commun. 27, 157-162.
25. Sloane, B. F., Rozhin, J., Johnson, K., Taylor, H., Crissman, J. D., & Honn, K. V. (1986) Proc. Natl Acad. Sci. U.S.A. 83, 2483-2487.
26. Sloane, B. F., Rozhin, J., Lah, T. T., Day. N. A., Buck, M., Ryan, R. E., Crissman, J. D., & Honn, K. V. (1988) Adv. Exp. Med. Biol. 233, 259-268.
27. Sloane, B. F. (1990) Semin. Cancer Biol. 1, 137-152.
28. Taralp, A., Kaplan, H., Sytwu, I.-I., Vlattas, I., Bohacek, R., Knap, A. K., Hirama, T., Huber, C. P., & Hasnain, S. (1995) J. Biol. Chem. 270, 18036-18043.
29. Trabandt, A., Gay, R. E., Fassbender, H. G., & Gay, S. (1991) Arthritis Rheum. 34, 1444-1451.
30. Turk, D., Podobnik, Popovič, T., Katunuma, N., Bode, W., Huber, R., & Turk, V. (1995) Biochemistry 34, 4791-4797.
31. Turk, D., Podobnik, M., Kuhelj, R., Dolinar, M., & Turk, V. (1996) FEBS Lett. 384, 211-214.
32. Yaron, A., Carmel, A., & Katchalski-Katzir, E. (1979) Anal. Biochem. 95, 228-235.