Cathepsins B1 and B2 in the neuropathogenic schistosome Trichobilharzia regenti: Distinct gene expression profiles and presumptive roles throughout the life cycle

Parasitology Research

Volumn 107, Issue 3, 2010, Pages 751-755

  Dolečková, Kateřina ^a   Albrecht, Tomáš ^a,b   Mikeš, Libor ^a   Horák, Petr ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

^b INSTITUTE OF VERTEBRATE BIOLOGY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN B; CATHEPSIN X; MESSENGER RNA;

ARTICLE; CERCARIA (TREMATODE LARVA); GENE EXPRESSION PROFILING; GENETIC TRANSCRIPTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE DEVELOPMENT; PRIORITY JOURNAL; PROTEIN FUNCTION; SCHISTOSOMA; SCHISTOSOMULUM; TREMATODE LIFE CYCLE STAGE; TRICHOBILHARZIA REGENTI;

ANIMALS; CATHEPSIN B; DUCKS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HELMINTH PROTEINS; ISOENZYMES; LIFE CYCLE STAGES; SCHISTOSOMATIDAE; SNAILS;

AVES; SCHISTOSOMA; TRICHOBILHARZIA REGENTI;

EID: 77955468898     PISSN: 09320113     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00436-010-1943-6     Document Type: Article

References (22)

1. K Blažová P Horák 2005 Trichobilharzia regenti: the developmental differences in natural and abnormal hosts Parasitol Int 54 3 167 172 10.1016/j.parint.2005.03.003 10.1016/j.parint.2005.03.003 15908263 (Pubitemid 40922913)
2. CR Caffrey JP Salter KD Lucas D Khiem I Hsieh KC Lim A Ruppel JH McKerrow M Sajid 2002 SmCB2, a novel tegumental cathepsin b from adult Schistosoma mansoni Mol Biochem Parasitol 121 1 49 61 10.1016/S0166-6851(02)00022-1 10.1016/S0166-6851(02)00022-1 1:CAS:528:DC%2BD38Xjt1SktLk%3D 11985862 (Pubitemid 34457833)
3. CR Caffrey JH McKerrow JP Salter M Sajid 2004 Blood 'n' guts: an update on schistosome digestive peptidases Trends Parasitol 20 5 241 248 10.1016/j.pt.2004.03.004 10.1016/j.pt.2004.03.004 1:CAS:528:DC%2BD2cXjtl2nt78%3D 15105025 (Pubitemid 38510321)
4. J Correnti P Brindley E Pearce 2005 Long-term suppression of cathepsin b levels by RNA interference retards schistosome growth Mol Biochem Parasitol 143 209 215 10.1016/j.pt.2004.03.004 10.1016/j.molbiopara.2005.06.007 1:CAS:528:DC%2BD2MXpsVCgsbY%3D 16076506
5. Dalton JP, Caffrey CR, Sajid M, Stack C, Donnelly S, Loukas A, Don T, McKerrow J, Halton DW, Brindley PJ (2006) Proteases in trematode biology. In: Maule AG, Marks NJ (eds) Parasitic flatworms: molecular biology, biochemistry, immunology and physiology. CAB International, Wallingford, pp 348-368
6. K Dolečková M Kašný L Mikeš F Mutapi C Stack AP Mountford P Horák 2007 Peptidases of Trichobilharzia regenti (schistosomatidae) and its molluscan host Radix peregra s. lat. (lymnaeidae): construction and screening of cDNA library from intramolluscan stages of the parasite Folia Parasitol (Praha) 54 94 98
7. K Dolečková M Kašný L Mikeš J Cartwright P Jedelský EL Schneider J Dvořák AP Mountford CS Craik P Horák 2009 The functional expression and characterisation of a cysteine peptidase from the invasive stage of the neuropathogenic schistosome Trichobilharzia regenti Int J Parasitol 39 2 201 211 10.1016/j.ijpara.2008.06. 010 10.1016/j.ijpara.2008.06.010 18708063
8. J Dvořák M Delcroix A Rossi V Vopálenský M Pospíšek M Šedinová L Mikeš M Sajid A Sali JH McKerrow P Horák CR Caffrey 2005 Multiple cathepsin b isoforms in schistosomula of Trichobilharzia regenti: identification, characterisation and putative role in migration and nutrition Int J Parasitol 35 8 895 910 10.1016/j.ijpara.2008.06.010 10.1016/j.ijpara.2005.02.018 15950230
9. Faraway JJ (2006) Extending the Linear Model with R: generalized linear, mixed effects and nonparametric regression models. Chapman & Hall/CRC, Boca Raton
10. W Haas A van de Roemer 1998 Invasion of the vertebrate skin by cercariae of Trichobilharzia ocellata: penetration processes and stimulating host signals Parasitol Res 84 10 787 795 10.1007/s004360050489 10.1007/s004360050489 1:STN:280:DyaK1M%2FhtFSrtA%3D%3D 9797062 (Pubitemid 28442780)
11. P Horák L Mikeš J Rudolfová L Kolář ová 2008 Penetration of Trichobilharzia cercariae into mammals: dangerous or negligible event? Parasite 15 3 299 303 18814698
12. K Hrádková P Horák 2002 Neurotropic behaviour of Trichobilharzia regenti in ducks and mice J Helminthol 76 2 137 141 10.1079/JOH2002113 10.1079/JOH2002113 12015826 (Pubitemid 34591843)
13. ER Jolly CS Chin S Miller MM Bahgat KC Lim J DeRisi JH McKerrow 2007 Gene expression patterns during adaptation of a helminth parasite to different environmental niches Genome Biol 8 4 R65 10.1079/JOH2002113 10.1186/gb-2007-8-4- r65 17456242
14. M Kašný L Mikeš V Hampl J Dvořák CR Caffrey JP Dalton P Horák 2009 Peptidases of trematodes Adv Parasitol 69 205 297 10.1016/S0065-308X(09)69004-7 10.1016/S0065-308X(09)69004-7 19622410
15. L Kolářová 2007 Schistosomes causing cercarial dermatitis: a mini-review of current trends in systematics and of host specificity and pathogenicity Folia Parasitol (Praha) 54 2 81 87
16. YL Li MA Idris M Corachan JJ Han M Kirschfink A Ruppel 1996 Circulating antigens in schistosomiasis: detection of 31/32-kDa proteins in sera from patients infected with Schistosoma japonicum, S. mansoni, S. haematobium, or S. intercalatum Parasitol Res 82 1 14 18 10.1007/s004360050060 10.1007/ s004360050060 1:STN:280:DyaK28vit1yhsw%3D%3D 8825438
17. MW Pfaffl 2001 A new mathematical model for relative quantification in real-time RT-PCR Nucleic Acids Res 29 9 e45 10.1093/nar/29.9.e45 10.1093/nar/29.9.e45 1:STN:280:DC%2BD38nis12jtw%3D%3D 11328886
18. R Development Core Team (2009) R: a language and environment for statistical computing. R Foundation for Statistical Computing, Vienna
19. A Ruppel HJ Diesfeld U Rother 1985 Immunoblot analysis of Schistosoma mansoni antigens with sera of schistosomiasis patients: diagnostic potential of an adult schistosome polypeptide Clin Exp Immunol 62 3 499 506 1:CAS:528:DyaL28Xos1Kgsg%3D%3D 3936655
20. M Sajid JH McKerrow 2002 Cysteine proteases of parasitic organisms Mol Biochem Parasitol 120 1 1 21 10.1016/S0166-6851(01)00438-8 10.1016/S0166- 6851(01)00438-8 1:CAS:528:DC%2BD38Xht1agsbo%3D 11849701
21. MM Wasilewski KC Lim J Phillips JH McKerrow 1996 Cysteine protease inhibitors block schistosome hemoglobin degradation in vitro and decrease worm burden and egg production in vivo Mol Biochem Parasitol 81 2 179 189 10.1016/0166-6851(96)02703-X 10.1016/0166-6851(96)02703-X 1:CAS:528: DyaK28XlvVeisrw%3D 8898333 (Pubitemid 26316559)
22. TP Yoshino MJ Lodes AA Rege CL Chappell 1993 Proteinase activity in miracidia, transformation excretory-secretory products, and primary sporocysts of Schistosoma mansoni J Parasitol 79 1 23 31 10.1016/0166-6851(96)02703-X 10.2307/3283272 1:CAS:528:DyaK3sXksVGms70%3D 8437057