Effect of IL-1β and TNF-αvs IL-13 on bronchial hyperresponsiveness, β 2-adrenergic responses and cellularity of bronchial alveolar lavage fluid

Autonomic and Autacoid Pharmacology

Volumn 31, Issue 3-4, 2011, Pages 37-49

  Horiba, M ^a   Qutna, N ^a   Gendapodi, P ^a   Agrawal, S ^a   Sapkota, K ^a   Abel, P ^a   Townley, R G ^a  

^a CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

2 adrenergic agonist; Bronchial asthma; Bronchial hyper responsiveness; Bronchial lavage and inflammatory cells; Cytokines (IL 1 ; Methacholine; Murine model; TNF and IL 13)

Indexed keywords

METHACHOLINE; OVALBUMIN; RECOMBINANT INTERLEUKIN 13; RECOMBINANT INTERLEUKIN 1BETA; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; SALBUTAMOL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRONCHOSPASM; BRONCHUS HYPERREACTIVITY; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFECT; DRUG SENSITIVITY; INFLAMMATORY INFILTRATE; LUNG LAVAGE; MOUSE; NONHUMAN;

ADRENERGIC BETA-2 RECEPTOR AGONISTS; ALBUTEROL; ANIMALS; BRONCHIAL HYPERREACTIVITY; BRONCHOALVEOLAR LAVAGE FLUID; BRONCHOCONSTRICTION; BRONCHOCONSTRICTOR AGENTS; BRONCHODILATOR AGENTS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; HUMANS; INTERLEUKIN-13; INTERLEUKIN-1BETA; MALE; METHACHOLINE CHLORIDE; MICE; MICE, INBRED BALB C; OVALBUMIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 80053288060     PISSN: 14748665     EISSN: 14748673     Source Type: Journal    
DOI: 10.1111/j.1474-8673.2011.00465.x     Document Type: Article

References (47)

1. AMMIT, A.J., HOFFMAN, R.K., AMRANI, Y., LAZAAR, A.L., HAY, D.W., TORPHY, T.J., PENN, R.B. & PANETTIERI, R.A., JR (2000). Tumor necrosis factor-alpha-induced secretion of RANTES and interleukin-6 from human airway smooth-muscle cells. Modulation by cyclic adenosine monophosphate. Am. J. Respir. Cell Mol. Biol., 23, 794-802.
2. BARRIO, J., CORTIJO, J., MILARA, J., MATA, M., GUIJARRO, R., BLASCO, P. & MORCILLO, E.J. (2006). In vitro tracheal hyperresponsiveness to muscarinic receptor stimulation by carbachol in a rat model of bleomycin-induced pulmonary fibrosis. Auton. Autacoid. Pharmacol., 26, 327-333.
3. BERRY, M.A., PARKER, D., NEALE, N., WOODMAN, L., MORGAN, A., MONK, P. et al. (2004). Sputum and bronchial submucosal IL-13 expression in asthma and eosinophilic bronchitis. J. Allergy Clin. Immunol., 114, 1106-1109.
4. BITTLEMAN, D.B. & CASALE, T.B. (1995). Interleukin-8 mediates interleukin-1 alpha-induced neutrophil transcellular migration. Am. J. Respir. Cell Mol. Biol., 13, 323-329.
5. BRYAN, S.A., LECKIE, M.J., HANSEL, T.T. & BARNES, P.J. (2000). Novel therapy for asthma. Expert Opin. Investig. Drugs, 9, 25-42.
6. CHONG, B.T., AGRAWAL, D.K., ROMERO, F.A. & TOWNLEY, R.G. (1998). An in vivo model of beta-adrenoceptor desensitization. J. Pharmacol. Toxicol. Methods, 40, 109-115.
7. CHOY, E.H. & PANAYI, G.S. (2001). Cytokine pathways and joint inflammation in rheumatoid arthritis. N. Eng. J. Med., 344, 907-916.
8. GRUNIG, G., WARNOCK, M., WAKIL, A.E. et al. (1998). Requirement for IL-13 independently of IL-4 in experimental asthma. Science (New York, N.Y.), 282, 2261-2263.
9. HAKONARSON, H., HALAPI, E., WHELAN, R., GULCHER, J., STEFANSSON, K. & GRUNSTEIN, M.M. (2001). Association between IL-1beta/TNF-alpha-induced glucocorticoid-sensitive changes in multiple gene expression and altered responsiveness in airway smooth muscle. Am. J. Respir. Cell Mol. Biol., 25, 761-771.
10. HAMELMANN, E., SCHWARZE, J., TAKEDA, K., OSHIBA, A., LARSEN, G.L., IRVIN, C.G. & GELFAND, E.W. (1997). Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography. Am. J. Respir. Crit. Care Med., 156(3 Pt 1): 766-775.
11. HOLGATE, S.T. (2004). Cytokine and anti-cytokine therapy for the treatment of asthma and allergic disease. Cytokine, 28, 152-157.
12. JIANG, H., ABEL, P.W., TOEWS, M.L., DENG, C., CASALE, T.B., XIE, Y. & TU, Y. (2010). Phosphoinositide 3-kinase gamma regulates airway smooth muscle contraction by modulating calcium oscillations. J. Pharmac. Exp. Ther., 334: 703-709.
13. KANEHIRO, A., LAHN, M., MAKELA, M.J., DAKHAMA, A., FUJITA, M., JOETHAM, A., MASON, R.J., BORN, W. & GELFAND, E.W. (2001). Tumor necrosis factor-alpha negatively regulates airway hyperresponsiveness through gamma-delta T cells. Am. J. Respir. Crit. Care Med., 164, 2229-2238.
14. KIM, E.Y., BATTAILE, J.T., PATEL, A.C., YOU, Y., AGAPOV, E., GRAYSON, M.H. et al. (2008). Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease. Nat. Med., 14, 633-640.
15. KUPERMAN, D.A., HUANG, X., KOTH, L.L., CHANG, G.H., DOLGANOV, G.M., ZHU, Z., ELIAS, J.A., SHEPPARD, D. & ERLE, D.J. (2002). Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma. Nat. Med., 8, 885-889.
16. MARTIN, C., UHLIG, S. & ULLRICH, V. (2001). Cytokine-induced bronchoconstriction in precision-cut lung slices is dependent upon cyclooxygenase-2 and thromboxane receptor activation. Am. J. Respir. Cell Mol. Biol., 24, 139-145.
17. MEDZHITOV, R. & JANEWAY, C., JR (2000). Innate immunity. N. Eng. J. Med., 343, 338-344.
18. MINTY, A., CHALON, P., DEROCQ, J.M. et al. (1993). Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses. Nature, 362, 248-250.
19. MITCHELL, J., DIMOV, V. & TOWNLEY, R.G. (2010). IL-13 and the IL-13 receptor as therapeutic targets for asthma and allergic disease. Curr. Opin. Investig. Drugs, 11: 527-534.
20. MOORE, P.E., LAHIRI, T., LAPORTE, J.D., CHURCH, T., PANETTIERI, R.A., JR & SHORE, S.A. (2001). Selected contribution: synergism between TNF-alpha and IL-1 beta in airway smooth muscle cells: implications for beta-adrenergic responsiveness. J. Appl. Physiol., 91, 1467-1474.
21. NAM, H.S., LEE, S.Y., KIM, S.J., KIM, J.S., KWON, S.S., KIM, Y.K. et al. (2009). The soluble tumor necrosis factor-alpha receptor suppresses airway inflammation in murine model of acute asthma. Yonsei Med. J., 50, 569-575.
22. NICOLETTI, F., MANCUSO, G., CUSUMANO, V., DI MARCO, R., ZACCONE, P., BENDTZEN, K. & TETI, G. (1997). Prevention of endotoxin-induced lethality in neonatal mice by interleukin-13. Eur. J. Immunol., 27, 1580-1583.
23. PANG, L. & KNOX, A.J. (2000). Synergistic inhibition by beta(2)-agonists and corticosteroids on tumor necrosis factor-alpha-induced interleukin-8 release from cultured human airway smooth-muscle cells. Am. J. Respir. Cell Mol. Biol., 23, 79-85.
24. POPE, S.M., BRANDT, E.B., MISHRA, A., HOGAN, S.P., ZIMMERMANN, N., MATTHAEI, K.I., FOSTER, P.S. & ROTHENBERG, M.E. (2001). IL-13 induces eosinophil recruitment into the lung by an IL-5- and eotaxin-dependent mechanism. J. Allergy Clin. Immunol., 108, 594-601.
25. RESSMEYER, A.R., BAI, Y., DELMOTTE, P., UY, K.F., THISTLETHWAITE, P., FRAIRE, A., SATO, O., IKEBE, M. & SANDERSON, M.J. (2010) Human airway contraction and formoterol-induced relaxation is determined by Ca2+ oscillations and Ca2+ sensitivity. Am. J. Respir. Cell Mol. Biol., 43: 179-191.
26. SAPERSTEIN, S., CHEN, L., OAKES, D., PRYHUBER, G. & FINKELSTEIN, J. (2009a). IL-1beta augments TNF-alpha-mediated inflammatory responses from lung epithelial cells. J. Interferon Cytokine Res., 29, 273-284.
27. SAPERSTEIN, S., HUYCK, H., KIMBALL, E., JOHNSTON, C., FINKELSTEIN, J. & PRYHUBER, G. (2009b). The effects of interleukin-1beta in tumor necrosis factor-alpha-induced acute pulmonary inflammation in mice. Mediators Inflamm., 2009, 958658.
28. SCHMITZ, J., OWYANG, A., OLDHAM, E. et al. (2005). IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity, 23, 479-490.
29. SMART, S.J. & CASALE, T.B. (1994). TNF-alpha-induced transendothelial neutrophil migration is IL-8 dependent. Am. J. Physiol. 266(3 Pt 1): L238-L245.
30. STRIETER, R.M., CHENSUE, S.W., BASHA, M.A., STANDIFORD, T.J., LYNCH, J.P., BAGGIOLINI, M. & KUNKEL, S.L. (1990). Human alveolar macrophage gene expression of interleukin-8 by tumor necrosis factor-alpha, lipopolysaccharide, and interleukin-1 beta. Am. J. Respir. Cell Mol. Biol., 2, 321-326.
31. SUZUKAWA, M., IIKURA, M., KOKETSU, R. et al. (2008). An IL-1 cytokine member, IL-33, induces human basophil activation via its ST2 receptor. J. Immunol., 181, 5981-5989.
32. THOMAS, P.S., YATES, D.H. & BARNES, P.J. (1995). Tumor necrosis factor-alpha increases airway responsiveness and sputum neutrophilia in normal human subjects. Am. J. Respir. Crit. Care Med., 152, 76-80.
33. TOMLINSON, K.L, DAVIES, G.C, SUTTON, D.J, PALFRAMAN, R.T. (2010). Neutralisation of interleukin-13 in mice prevents airway pathology caused by chronic exposure to house dust mite. PLoS One., 5, 13136.
34. TOWNLEY, R.G. (2007). Interleukin 13 and the beta-adrenergic blockade theory of asthma revisited 40years later. Ann. Allergy Asthma Immunol., 99, 215-224.
35. TOWNLEY, R.G. & HORIBA, M. (2003). Airway hyperresponsiveness: a story of mice and men and cytokines. Clin. Rev. Allergy Immunol., 24, 85-110.
36. TOWNLEY, R.G., GENDAPODI, P.R., QUTNA, N., EVANS, J., ROMERO, F.A. & ABEL, P. (2009). Effect of interleukin 13 on bronchial hyperresponsiveness and the bronchoprotective effect of beta-adrenergic bronchodilators and corticosteroids. Ann. Allergy Asthma Immunol., 102, 190-197.
37. TSUKAGOSHI, H., SAKAMOTO, T., XU, W., BARNES, P.J. & CHUNG, K.F. (1994). Effect of interleukin-1 beta on airway hyperresponsiveness and inflammation in sensitized and nonsensitized Brown-Norway rats. J. Allergy Clin. Immunol., 93, 464-469.
38. De WAAL MALEFYT, R., FIGDOR, C.G., HUIJBENS, R., MOHAN-PETERSON, S., BENNETT, B., CULPEPPER, J., DANG, W., ZURAWSKI, G. & De VRIES, J.E. (1993). Effects of IL-13 on phenotype, cytokine production, and cytotoxic function of human monocytes. Comparison with IL-4 and modulation by IFN-gamma or IL-10. J. Immunol., 151, 6370-6381.
39. WENZEL, S., WILBRAHAM, D., FULLER, R., GETZ, E.B. & LONGPHRE, M. (2007). Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: results of two phase 2a studies. Lancet, 370, 1422-1431.
40. WILLS-KARP, M., LUYIMBAZI, J., XU, X., SCHOFIELD, B., NEBEN, T.Y., KARP, C.L. & DONALDSON, D.D. (1998). Interleukin-13: central mediator of allergic asthma. Science (New York, N.Y.), 282, 2258-2261.
41. WILLS-KARP, M. (2004). Interleukin-13 in asthma pathogenesis. Immunol Rev., 202, 175-190.
42. XU, W.B., HADDAD, E.B., TSUKAGOSHI, H., ADCOCK, I., BARNES, P.J. & CHUNG, K.F. (1995). Induction of macrophage inflammatory protein 2 gene expression by interleukin 1 beta in rat lung. Thorax, 50, 1136-1140.
43. YANAGAWA, H., SONE, S., HAKU, T., MIZUNO, K., YANO, S., OHMOTO, Y. & OGURA, T. (1995). Contrasting effect of interleukin-13 on interleukin-1 receptor antagonist and proinflammatory cytokine production by human alveolar macrophages. Am. J. Respir. Cell Mol. Biol., 12, 71-76.
44. YANG, M., HOGAN, S.P., HENRY, P.J., MATTHAEI, K.I., McKENZIE, A.N., YOUNG, I.G., ROTHENBERG, M.E. & FOSTER, P.S. (2001). Interleukin-13 mediates airways hyperreactivity through the IL-4 receptor-alpha chain and STAT-6 independently of IL-5 and eotaxin. Am. J. Respir. Cell Mol. Biol., 25, 522-530.
45. ZAITSU, M., HAMASAKI, Y., MATSUO, M. et al. (2000). New induction of leukotriene A(4) hydrolase by interleukin-4 and interleukin-13 in human polymorphonuclear leukocytes. Blood, 96, 601-609.
46. ZHANG, Y., ADNER, M. & CARDELL, L.O. (2007a). IL-1beta-induced transcriptional up-regulation of bradykinin B1 and B2 receptors in murine airways. Am. J. Respir. Cell Mol. Biol., 36, 697-705.
47. ZHANG, Y., CARDELL, L.O. & ADNER, M. (2007b). IL-1beta induces murine airway 5-HT2A receptor hyperresponsiveness via a non-transcriptional MAPK-dependent mechanism. Respir. Res., 8, 29.