Antinociceptive effect of Brazilian armed spider venom toxin Tx3-3 in animal models of neuropathic pain

Pain

Volumn 152, Issue 10, 2011, Pages 2224-2232

  Dalmolin, Gerusa Duarte ^a   Silva, Cássia Regina ^b   Rigo, Flávia Karine ^a   Gomes, Guilherme Monteiro ^b   Cordeiro, Marta Do Nascimento ^c   Richardson, Michael ^c   Silva, Marco Aurélio Romano ^a   Prado, Marco Antonio Máximo ^a,d   Gomez, Marcus Vinicius ^a,e   Ferreira, Juliano ^a,b  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b FEDERAL UNIVERSITY OF SANTA MARIA   (Brazil)

^c Centro de Pesquisa e Desenvolvimento   (Brazil)

^d ROBARTS RESEARCH INSTITUTE   (Canada)

^e Núcleo de Pós graduaão ^*  (Brazil)

Author keywords

Antinociception; Calcium channel blocker; Neuropathic pain; P Q type calcium channel; Peptide toxin; R type calcium channel

Indexed keywords

ANALGESIC AGENT; CALCIUM CHANNEL N TYPE; CALCIUM CHANNEL P TYPE; CALCIUM CHANNEL Q TYPE; CALCIUM CHANNEL R TYPE; FREUND ADJUVANT; MORPHINE SULFATE; OMEGA CONOTOXIN MVIIC; SPIDER VENOM; SPIDER VENOM TX3 3; STREPTOZOCIN; UNCLASSIFIED DRUG;

ALLODYNIA; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; CONUS MAGUS; DIABETIC NEUROPATHY; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; FEMALE; INFLAMMATION; INFLAMMATORY PAIN; MALE; MOTOR DYSFUNCTION; MOTOR PERFORMANCE; MOUSE; MUSCLE FUNCTION; NERVE LIGATION; NEUROPATHIC PAIN; NOCICEPTION; NONHUMAN; PAIN; PERIPHERAL NERVE INJURY; PHONEUTRIA NIGRIVENTER; PRIORITY JOURNAL; RAT; ROTAROD TEST; SCIATIC NEUROPATHY; SPIDER; TAIL FLICK TEST;

ANALGESICS; ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; MALE; MICE; NEURALGIA; NEUROPEPTIDES; NEUROTOXINS; NOCICEPTORS; RATS; RATS, WISTAR; SPIDER VENOMS;

EID: 80053180081     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1016/j.pain.2011.04.015     Document Type: Article

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