Analgesic effect in rodents of native and recombinant Phα1β toxin, a high-voltage-activated calcium channel blocker isolated from armed spider venom

Pain

Volumn 140, Issue 1, 2008, Pages 115-126

  Souza, Alessandra H ^a   Ferreira, Juliano ^b   Cordeiro, Marta do Nascimento ^c   Vieira, Luciene Bruno ^a   De Castro, Celio J ^a   Trevisan, Gabriela ^b   Reis, Helton ^a   Souza, Ivana Assis ^a   Richardson, Michael ^c   Prado, Marco A M ^a,e   Prado, Vânia F ^a,e   Gomez, Marcus Vinicius ^d,f  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b FEDERAL UNIVERSITY OF SANTA MARIA   (Brazil)

^c FUNDAÇÃO EZEQUIEL DIAS   (Brazil)

^d Santa Casa de Belo Horizonte ^*  (Brazil)

^e ROBARTS RESEARCH INSTITUTE   (Canada)

^f UFMG   (Brazil)

Author keywords

Conotoxin MVIIA; Analgesic action; Phoneutria toxin; Recombinant toxin; Side effects

Indexed keywords

ANALGESIC AGENT; CALCIUM CHANNEL BLOCKING AGENT; GLUTAMIC ACID; NEUROTRANSMITTER; OMEGA CONOTOXIN MVIIA; PHALPHA1BETA TOXIN; SPIDER VENOM; UNCLASSIFIED DRUG;

ANALGESIA; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CEREBROSPINAL FLUID; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; DRUG SAFETY; ESCHERICHIA COLI; MALE; MOUSE; NEUROPATHIC PAIN; NONHUMAN; PAIN; PRIORITY JOURNAL; PROTEIN ISOLATION; SPINAL CORD; SYNAPTOSOME;

ANALGESICS; ANIMALS; CALCIUM CHANNEL BLOCKERS; ESCHERICHIA COLI; HYPERALGESIA; MALE; MICE; PAIN MEASUREMENT; RECOMBINANT PROTEINS; SPIDER VENOMS;

EID: 54449084355     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pain.2008.07.014     Document Type: Article

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