The Cav2.3 calcium channel antagonist SNX-482 reduces dorsal horn neuronal responses in a rat model of chronic neuropathic pain

European Journal of Neuroscience

Volumn 25, Issue 12, 2007, Pages 3561-3569

  Matthews, Elizabeth A ^a   Bee, Lucy A ^a   Stephens, Gary J ^b   Dickenson, Anthony H ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF READING   (United Kingdom)

Author keywords

Analgesia; CaV2.3; Nerve injury; Nociception; R type calcium current; Sprague Dawley rat

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; SNX 482; VOLTAGE GATED CALCIUM CHANNEL; CACNA1E PROTEIN, RAT; CALCIUM CHANNEL R TYPE; CATION TRANSPORT PROTEIN; SPIDER VENOM; UNCLASSIFIED DRUG;

AFFERENT NERVE GROUP 1; ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN ELECTROPHYSIOLOGY; CHRONIC PAIN; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; DRUG POTENCY; DRUG SELECTIVITY; ELECTROSTIMULATION; HINDLIMB; MALE; NERVE CELL EXCITABILITY; NERVE FIBER C; NERVE INJURY; NERVE LIGATION; NEUROPATHIC PAIN; NOCICEPTIVE STIMULATION; NONHUMAN; PAIN THRESHOLD; PRIORITY JOURNAL; RAT; SPINAL CORD DORSAL HORN; THERAPY EFFECT; THERMAL STIMULATION; TREATMENT OUTCOME; TREATMENT RESPONSE; ANIMAL; ANIMAL BEHAVIOR; DISEASE MODEL; EVOKED RESPONSE; METHODOLOGY; NEURALGIA; PAIN ASSESSMENT; PATHOLOGY; PHYSIOLOGY; POSTERIOR HORN CELL; RADIATION EXPOSURE; SPINAL CORD INJURY; SPRAGUE DAWLEY RAT;

ANIMALS; BEHAVIOR, ANIMAL; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, R-TYPE; CATION TRANSPORT PROTEINS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; EVOKED POTENTIALS; MALE; NEURALGIA; PAIN MEASUREMENT; POSTERIOR HORN CELLS; RATS; RATS, SPRAGUE-DAWLEY; SPIDER VENOMS; SPINAL CORD INJURIES;

EID: 34347389926     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2007.05605.x     Document Type: Article

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