-
1
-
-
1242284388
-
Arachidonic acid, palmitic acid and glucose are important for the modulation of clonal pancreatic β-cell insulin secretion, growth and functional integrity
-
DOI 10.1042/CS20030261
-
Dixon G, Nolan J, McClenaghan NH, Flatt PR, Newsholme P 2004 Arachidonic acid, palmitic acid and glucose are important for the modulation of clonal pancreatic β-cell insulin secretion, growth and functional integrity. Clin Sci (Lond) 106:191-199 (Pubitemid 38223438)
-
(2004)
Clinical Science
, vol.106
, Issue.2
, pp. 191-199
-
-
Dixon, G.1
Nolan, J.2
McClenaghan, N.H.3
Flatt, P.R.4
Newsholme, P.5
-
2
-
-
0031767793
-
Soybean- and olive-oils-enriched diets increase insulin secretion to glucose stimulus in isolated pancreatic rat islets
-
DOI 10.1016/S0031-9384(98)00157-7, PII S0031938498001577
-
Picinato MC, Curi R, Machado UF, Carpinelli AR 1998 Soybean-and olive-oils-enriched diets increase insulin secretion to glucose stimulus in isolated pancreatic rat islets. Physiol Behav 65:289-294 (Pubitemid 28548650)
-
(1998)
Physiology and Behavior
, vol.65
, Issue.2
, pp. 289-294
-
-
Picinato, M.C.1
Curi, R.2
Machado, U.F.3
Carpinelli, A.R.4
-
3
-
-
0036233109
-
Acute effects of fatty acids on insulin secretion from rat and human islets of Langerhans
-
DOI 10.1677/joe.0.1730073
-
Gravena C, Mathias PC, Ashcroft SJ 2002 Acute effects of fatty acids on insulin secretion from rat and human islets of Langerhans. J Endocrinol 173:73-80 (Pubitemid 34428893)
-
(2002)
Journal of Endocrinology
, vol.173
, Issue.1
, pp. 73-80
-
-
Gravena, C.1
Mathias, P.C.2
Ashcroft, S.J.H.3
-
4
-
-
0034457523
-
Long-chain acyl CoA regulation of protein kinase C and fatty acid potentiation of glucose-stimulated insulin secretion in clonal β-cells
-
DOI 10.1210/en.141.6.1989
-
Yaney GC, Korchak HM, Corkey BE 2000 Long-chain acyl CoA regulation of protein kinase C and fatty acid potentiation of glucose-stimulated insulin secretion in clonal β-cells. Endocrinology 141:1989-1998 (Pubitemid 32274347)
-
(2000)
Endocrinology
, vol.141
, Issue.6
, pp. 1989-1998
-
-
Yaney, G.C.1
Korchak, H.M.2
Corkey, B.E.3
-
5
-
-
79251492010
-
NAD(P)H oxidase participates in the palmitate-induced superoxide production and insulin secretion by rat pancreatic islets
-
Graciano MF, Santos LR, Curi R, Carpinelli AR 2011 NAD(P)H oxidase participates in the palmitate-induced superoxide production and insulin secretion by rat pancreatic islets. Journal of cellular physiology 226:1110-1117
-
(2011)
Journal of Cellular Physiology
, vol.226
, pp. 1110-1117
-
-
Graciano, M.F.1
Santos, L.R.2
Curi, R.3
Carpinelli, A.R.4
-
6
-
-
24344486460
-
Oleate prevents palmitate-induced cytotoxic stress in cardiac myocytes
-
DOI 10.1016/j.bbrc.2005.08.088, PII S0006291X0501781X
-
Miller TA, LeBrasseur NK, Cote GM, Trucillo MP, Pimentel DR, Ido Y, Ruderman NB, Sawyer DB 2005 Oleate prevents palmitate-induced cytotoxic stress in cardiac myocytes. Biochem Biophys Res Commun 336:309-315 (Pubitemid 41253435)
-
(2005)
Biochemical and Biophysical Research Communications
, vol.336
, Issue.1
, pp. 309-315
-
-
Miller, T.A.1
LeBrasseur, N.K.2
Cote, G.M.3
Trucillo, M.P.4
Pimentel, D.R.5
Ido, Y.6
Ruderman, N.B.7
Sawyer, D.B.8
-
7
-
-
33746190686
-
Fatty acid-induced toxicity and neutral lipid accumulation in insulin-producing RINm5F cells
-
DOI 10.1016/j.tiv.2006.02.007, PII S088723330600035X
-
Azevedo-Martins AK, Monteiro AP, Lima CL, Lenzen S, Curi R 2006 Fatty acid-induced toxicity and neutral lipid accumulation in insulin-producing RINm5F cells. Toxicol In Vitro 20:1106-1113 (Pubitemid 44088590)
-
(2006)
Toxicology in Vitro
, vol.20
, Issue.7
, pp. 1106-1113
-
-
Azevedo-Martins, A.K.1
Monteiro, A.P.2
Lima, C.L.3
Lenzen, S.4
Curi, R.5
-
8
-
-
0031712798
-
+-ATP channel-independent pathway of regulation of insulin secretion by glucose: In search of the underlying mechanism
-
DOI 10.2337/diabetes.47.11.1713
-
Sato Y, Henquin JC 1998 The K+-ATP channel-independent pathway of regulation of insulin secretion by glucose: in search of the underlying mechanism. Diabetes 47:1713-1721 (Pubitemid 28476245)
-
(1998)
Diabetes
, vol.47
, Issue.11
, pp. 1713-1721
-
-
Sato, Y.1
Henquin, J.-C.2
-
10
-
-
0015882267
-
Stimulation of insulin secretion by long-chain free fatty acids. A direct pancreatic effect
-
Crespin SR, Greenough 3rd WB, Steinberg D 1973 Stimulation of insulin secretion by long-chain free fatty acids. A direct pancreatic effect. J Clin Invest 52:1979-1984
-
(1973)
J Clin Invest
, vol.52
, pp. 1979-1984
-
-
Crespin, S.R.1
Greenough III, W.B.2
Steinberg, D.3
-
11
-
-
0037838892
-
The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids
-
DOI 10.1074/jbc.M211495200
-
Briscoe CP, Tadayyon M, Andrews JL, Benson WG, Chambers JK, Eilert MM, Ellis C, Elshourbagy NA, Goetz AS, Minnick DT, Murdock PR, Sauls Jr HR, Shabon U, Spinage LD, Strum JC, Szekeres PG, Tan KB, Way JM, Ignar DM, Wilson S, Muir AI 2003 The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids. J Biol Chem 278:11303-11311 (Pubitemid 36792687)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.13
, pp. 11303-11311
-
-
Briscoe, C.P.1
Tadayyon, M.2
Andrews, J.L.3
Benson, W.G.4
Chambers, J.K.5
Eilert, M.M.6
Ellis, C.7
Elshourbagy, N.A.8
Goetz, A.S.9
Minnick, D.T.10
Murdock, P.R.11
Sauls Jr., H.R.12
Shabon, U.13
Spinage, L.D.14
Strum, J.C.15
Szekeres, P.G.16
Tan, K.B.17
Way, J.M.18
Ignar, D.M.19
Wilson, S.20
Muir, A.I.21
more..
-
12
-
-
65549114432
-
Overexpression of GPR40 in pancreatic β-cells augments glucose-stimulated insulin secretion and improves glucose tolerance in normal and diabetic mice
-
Nagasumi K, Esaki R, Iwachidow K, Yasuhara Y, Ogi K, Tanaka H, Nakata M, Yano T, Shimakawa K, Taketomi S, Takeuchi K, Odaka H, Kaisho Y 2009 Overexpression of GPR40 in pancreatic β-cells augments glucose-stimulated insulin secretion and improves glucose tolerance in normal and diabetic mice. Diabetes 58:1067-1076
-
(2009)
Diabetes
, vol.58
, pp. 1067-1076
-
-
Nagasumi, K.1
Esaki, R.2
Iwachidow, K.3
Yasuhara, Y.4
Ogi, K.5
Tanaka, H.6
Nakata, M.7
Yano, T.8
Shimakawa, K.9
Taketomi, S.10
Takeuchi, K.11
Odaka, H.12
Kaisho, Y.13
-
13
-
-
20944433543
-
The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse
-
DOI 10.1016/j.cmet.2005.03.007, PII S1550413105000860
-
Steneberg P, Rubins N, Bartoov-Shifman R, Walker MD, Edlund H 2005 The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse. Cell Metab 1:245-258 (Pubitemid 43960613)
-
(2005)
Cell Metabolism
, vol.1
, Issue.4
, pp. 245-258
-
-
Steneberg, P.1
Rubins, N.2
Bartoov-Shifman, R.3
Walker, M.D.4
Edlund, H.5
-
16
-
-
34347399043
-
Reactive oxygen species as a signal in glucose-stimulated insulin secretion
-
DOI 10.2337/db06-1601
-
Pi J, Bai Y, Zhang Q, Wong V, Floering LM, Daniel K, Reece JM, Deeney JT, Andersen ME, Corkey BE, Collins S 2007 Reactive oxygen species as a signal in glucose-stimulated insulin secretion. Diabetes 56:1783-1791 (Pubitemid 47025446)
-
(2007)
Diabetes
, vol.56
, Issue.7
, pp. 1783-1791
-
-
Pi, J.1
Bai, Y.2
Zhang, Q.3
Wong, V.4
Floering, L.M.5
Daniel, K.6
Reece, J.M.7
Deeney, J.T.8
Andersen, M.E.9
Corkey, B.E.10
Collins, S.11
-
17
-
-
34250340017
-
Glucose, palmitate and pro-inflammatory cytokines modulate production and activity of a phagocyte-like NADPH oxidase in rat pancreatic islets and a clonal β-cell line
-
Morgan D, Oliveira-Emilio HR, Keane D, Hirata AE, Santos da Rocha M, Bordin S, Curi R, Newsholme P, Carpinelli AR 2007 Glucose, palmitate and pro-inflammatory cytokines modulate production and activity of a phagocyte-like NADPH oxidase in rat pancreatic islets and a clonal β-cell line. Diabetologia 50:359-369
-
(2007)
Diabetologia
, vol.50
, pp. 359-369
-
-
Morgan, D.1
Oliveira-Emilio, H.R.2
Keane, D.3
Hirata, A.E.4
Santos Da Rocha, M.5
Bordin, S.6
Curi, R.7
Newsholme, P.8
Carpinelli, A.R.9
-
18
-
-
66449112021
-
Association of NAD(P)H oxidase with glucose-induced insulin secretion by pancreatic β-cells
-
Morgan D, Rebelato E, Abdulkader F, Graciano MF, Oliveira- Emilio HR, Hirata AE, Rocha MS, Bordin S, Curi R, Carpinelli AR 2009 Association of NAD(P)H oxidase with glucose-induced insulin secretion by pancreatic β-cells. Endocrinology 150:2197-2201
-
(2009)
Endocrinology
, vol.150
, pp. 2197-2201
-
-
Morgan, D.1
Rebelato, E.2
Abdulkader, F.3
Graciano, M.F.4
Oliveira-Emilio, H.R.5
Hirata, A.E.6
Rocha, M.S.7
Bordin, S.8
Curi, R.9
Carpinelli, A.R.10
-
19
-
-
34547830983
-
Diabetes associated cell stress and dysfunction: Role of mitochondrial and non-mitochondrial ROS production and activity
-
DOI 10.1113/jphysiol.2007.135871
-
Newsholme P, Haber EP, Hirabara SM, Rebelato EL, Procopio J, Morgan D, Oliveira-Emilio HC, Carpinelli AR, Curi R 2007 Diabetes associated cell stress and dysfunction: role of mitochondrial and non-mitochondrial ROS production and activity. J Physiol 583:9-24 (Pubitemid 47244241)
-
(2007)
Journal of Physiology
, vol.583
, Issue.1
, pp. 9-24
-
-
Newsholme, P.1
Haber, E.P.2
Hirabara, S.M.3
Rebelato, E.L.O.4
Procopio, J.5
Morgan, D.6
Oliveira-Emilio, H.C.7
Carpinelli, A.R.8
Curi, R.9
-
20
-
-
0038165514
-
Mitochondrial functional state in clonal pancreatic β-cells exposed to free fatty acids
-
DOI 10.1074/jbc.M209709200
-
Koshkin V, Wang X, Scherer PE, Chan CB, Wheeler MB 2003 Mitochondrial functional state in clonal pancreatic β-cells exposed to free fatty acids. J Biol Chem 278:19709-19715 (Pubitemid 36799156)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.22
, pp. 19709-19715
-
-
Koshkin, V.1
Wang, X.2
Scherer, P.E.3
Chan, C.B.4
Wheeler, M.B.5
-
21
-
-
77949322975
-
Electron transport chain-dependent and -independent mechanisms of mitochondrial H2O2 emission during long-chain fatty acid oxidation
-
Seifert EL, Estey C, Xuan JY, Harper ME 2010 Electron transport chain-dependent and -independent mechanisms of mitochondrial H2O2 emission during long-chain fatty acid oxidation. J Biol Chem 285:5748-5758
-
(2010)
J Biol Chem
, vol.285
, pp. 5748-5758
-
-
Seifert, E.L.1
Estey, C.2
Xuan, J.Y.3
Harper, M.E.4
-
22
-
-
0037645789
-
Pancreatic β-cells express phagocyte-like NAD(P)H oxidase
-
DOI 10.2337/diabetes.52.6.1457
-
Oliveira HR, Verlengia R, Carvalho CR, Britto LR, Curi R, Carpinelli AR 2003 Pancreatic β-cells express phagocyte-like NA-D(P)H oxidase. Diabetes 52:1457-1463 (Pubitemid 36666201)
-
(2003)
Diabetes
, vol.52
, Issue.6
, pp. 1457-1463
-
-
Oliveira, H.R.1
Verlengia, R.2
Carvalho, C.R.O.3
Britto, L.R.G.4
Curi, R.5
Carpinelli, A.R.6
-
23
-
-
0033105874
-
NADPH oxidase: An update
-
Babior BM 1999 NADPH oxidase: an update. Blood 93:1464-1476 (Pubitemid 29102471)
-
(1999)
Blood
, vol.93
, Issue.5
, pp. 1464-1476
-
-
Babior, B.M.1
-
24
-
-
33845194611
-
Expression of isoforms of NADPH oxidase components in rat pancreatic islets
-
DOI 10.1016/j.lfs.2006.08.031, PII S0024320506006746
-
Uchizono Y, Takeya R, Iwase M, Sasaki N, Oku M, Imoto H, Iida M, Sumimoto H 2006 Expression of isoforms of NADPH oxidase components in rat pancreatic islets. Life Sci 80:133-139 (Pubitemid 44853977)
-
(2006)
Life Sciences
, vol.80
, Issue.2
, pp. 133-139
-
-
Uchizono, Y.1
Takeya, R.2
Iwase, M.3
Sasaki, N.4
Oku, M.5
Imoto, H.6
Iida, M.7
Sumimoto, H.8
-
25
-
-
70949087785
-
Insights into the critical role of NADPH oxidase(s) in the normal and dysregulated pancreatic β-cell
-
Newsholme P, Morgan D, Rebelato E, Oliveira-Emilio HC, Procopio J, Curi R, Carpinelli A 2009 Insights into the critical role of NADPH oxidase(s) in the normal and dysregulated pancreatic β-cell. Diabetologia 52:2489-2498
-
(2009)
Diabetologia
, vol.52
, pp. 2489-2498
-
-
Newsholme, P.1
Morgan, D.2
Rebelato, E.3
Oliveira-Emilio, H.C.4
Procopio, J.5
Curi, R.6
Carpinelli, A.7
-
26
-
-
54349114273
-
2+ dynamics in pancreatic β-cells
-
2+ dynamics in pancreatic β-cells. Endocrinology 149:5391-5400
-
(2008)
Endocrinology
, vol.149
, pp. 5391-5400
-
-
Imoto, H.1
Sasaki, N.2
Iwase, M.3
Nakamura, U.4
Oku, M.5
Sonoki, K.6
Uchizono, Y.7
Iida, M.8
-
27
-
-
18144447696
-
Protein kinase C-dependent increase in reactive oxygen species (ROS) production in vascular tissues of diabetes: Role of vascular NAD(P)H oxidase
-
Inoguchi T, Sonta T, Tsubouchi H, Etoh T, Kakimoto M, Sonoda N, Sato N, Sekiguchi N, Kobayashi K, Sumimoto H, Utsumi H, Nawata H 2003 Protein kinase C-dependent increase in reactive oxygen species (ROS) production in vascular tissues of diabetes: role of vascular NAD(P)H oxidase. J Am Soc Nephrol 14:S227-S232 (Pubitemid 36903930)
-
(2003)
Journal of the American Society of Nephrology
, vol.14
, Issue.SUPPL. 3
-
-
Inoguchi, T.1
Sonta, T.2
Tsubouchi, H.3
Etoh, T.4
Kakimoto, M.5
Sonoda, N.6
Sato, N.7
Sekiguchi, N.8
Kobayashi, K.9
Sumimoto, H.10
Utsumi, H.11
Nawata, H.12
-
28
-
-
0014042613
-
Method for the isolation of intact islets of Langerhans from the rat pancreas
-
Lacy PE, Kostianovsky M 1967 Method for the isolation of intact islets of Langerhans from the rat pancreas. Diabetes 16:35-39
-
(1967)
Diabetes
, vol.16
, pp. 35-39
-
-
Lacy, P.E.1
Kostianovsky, M.2
-
29
-
-
0842291578
-
Glucose Sensitivity and Metabolism-Secretion Coupling Studied during Two-Year Continuous Culture in INS-1E Insulinoma Cells
-
DOI 10.1210/en.2003-1099
-
Merglen A, Theander S, Rubi B, Chaffard G, Wollheim CB, Maechler P 2004 Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells. Endocrinology 145:667-678 (Pubitemid 38183809)
-
(2004)
Endocrinology
, vol.145
, Issue.2
, pp. 667-678
-
-
Merglen, A.1
Theander, S.2
Rubi, B.3
Chaffard, G.4
Wollheim, C.B.5
Maechler, P.6
-
30
-
-
59949085548
-
Angiotensin II induces superoxide generation via NAD(P)H oxidase activation in isolated rat pancreatic islets
-
Hirata AE, Morgan D, Oliveira-Emilio HR, Rocha MS, Carvalho CR, Curi R, Carpinelli AR 2009 Angiotensin II induces superoxide generation via NAD(P)H oxidase activation in isolated rat pancreatic islets. Regul Pept 153:1-6
-
(2009)
Regul Pept
, vol.153
, pp. 1-6
-
-
Hirata, A.E.1
Morgan, D.2
Oliveira-Emilio, H.R.3
Rocha, M.S.4
Carvalho, C.R.5
Curi, R.6
Carpinelli, A.R.7
-
31
-
-
76249130823
-
Low doses of hydrogen peroxide impair glucose-stimulated insulin secretion via inhibition of glucose metabolism and intracellular calcium oscillations
-
Rebelato E, Abdulkader F, Curi R, Carpinelli AR 2010 Low doses of hydrogen peroxide impair glucose-stimulated insulin secretion via inhibition of glucose metabolism and intracellular calcium oscillations. Metabolism 59:409-413
-
(2010)
Metabolism
, vol.59
, pp. 409-413
-
-
Rebelato, E.1
Abdulkader, F.2
Curi, R.3
Carpinelli, A.R.4
-
32
-
-
0029888870
-
Essentiality of circulating fatty acids for glucose-stimulated insulin secretion in the fasted rat
-
Stein DT, Esser V, Stevenson BE, Lane KE, Whiteside JH, Daniels MB,Chen S, McGarry JD 1996 Essentiality of circulating fatty acids for glucose-stimulated insulin secretion in the fasted rat. J Clin Invest 97:2728-2735 (Pubitemid 26197087)
-
(1996)
Journal of Clinical Investigation
, vol.97
, Issue.12
, pp. 2728-2735
-
-
Stein, D.T.1
Esser, V.2
Stevenson, B.E.3
Lane, K.E.4
Whiteside, J.H.5
Daniels, M.B.6
Chen, S.7
McGarry, J.D.8
-
33
-
-
32544439719
-
Comparative toxicity of oleic and linoleic acid on human lymphocytes
-
Cury-Boaventura MF, Gorjão R, de Lima TM, Newsholme P, Curi R 2006 Comparative toxicity of oleic and linoleic acid on human lymphocytes. Life Sci 78:1448-1456
-
(2006)
Life Sci
, vol.78
, pp. 1448-1456
-
-
Cury-Boaventura, M.F.1
Gorjão, R.2
De Lima, T.M.3
Newsholme, P.4
Curi, R.5
-
34
-
-
78649660058
-
Different effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: Role of oxidative stress
-
Yuzefovych L, Wilson G, Rachek L 2010 Different effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: role of oxidative stress. Am J Physiol 299:E1096-E1105
-
(2010)
Am J Physiol
, vol.299
-
-
Yuzefovych, L.1
Wilson, G.2
Rachek, L.3
-
35
-
-
0032452225
-
Regulatory interactions between lipids and carbohydrates: The glucose fatty acid cycle after 35 years
-
DOI 10.1002/(SICI)1099-0895(199812)14:4<263::AID-DMR233>3.0.CO;2-C
-
Randle PJ 1998 Regulatory interactions between lipids and carbohydrates: the glucose fatty acid cycle after 35 years. Diabetes Metab Rev 14:263-283 (Pubitemid 29110250)
-
(1998)
Diabetes/Metabolism Reviews
, vol.14
, Issue.4
, pp. 263-283
-
-
Randle, P.J.1
-
36
-
-
11144262144
-
Perspective: Emerging evidence for signaling roles of mitochondrial anaplerotic products in insulin secretion
-
DOI 10.1152/ajpendo.00218.2004
-
MacDonald MJ, Fahien LA, Brown LJ, Hasan NM, Buss JD, Kendrick MA 2005 Perspective: emerging evidence for signaling roles of mitochondrial anaplerotic products in insulin secretion. Am J Physiol 288:E1-E15 (Pubitemid 40023785)
-
(2005)
American Journal of Physiology - Endocrinology and Metabolism
, vol.288
, Issue.1
-
-
MacDonald, M.J.1
Fahien, L.A.2
Brown, L.J.3
Hasan, N.M.4
Buss, J.D.5
Kendrick, M.A.6
-
37
-
-
0030589626
-
Reactive oxygen species-mediated inactivation of pyruvate dehydrogenase
-
DOI 10.1006/abbi.1996.0560
-
Tabatabaie T, Potts JD, Floyd RA 1996 Reactive oxygen species-mediated inactivation of pyruvate dehydrogenase. Arch Biochem Biophys 336:290-296 (Pubitemid 26428244)
-
(1996)
Archives of Biochemistry and Biophysics
, vol.336
, Issue.2
, pp. 290-296
-
-
Tabatabaie, T.1
Potts, J.D.2
Floyd, R.A.3
|