Naphthalene-induced respiratory tract toxicity: Metabolic mechanisms of toxicity

Drug Metabolism Reviews

Volumn 34, Issue 4, 2002, Pages 791-820

  Buckpitt, A ^a   Boland, B ^a   Isbell, M ^a   Morin, D ^a   Shultz, M ^a   Baldwin, R ^a   Chan, K ^a   Karlsson, A ^a   Lin, C ^a   Taff, A ^a   West, J ^a   Fanucchi, M ^a   Van Winkle, L ^a   Plopper, C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Clara cell toxicity; Covalent binding; CYP2F; Human; Lung; Naphthalene; Naphthalene epoxide; Naphthoguinone; Rodent cytochrome P450

Indexed keywords

1 NAPHTHOL; 4 IPOMEANOL; CELL PROTEIN; CYTOCHROME P450; EPOXIDE HYDROLASE; FURAN; GLUTATHIONE; GLUTATHIONE TRANSFERASE; NAPHTHALENE; NAPHTHALENE DERIVATIVE;

ACUTE TOXICITY; ANIMAL MODEL; BIOASSAY; BIOTRANSFORMATION; CARCINOGENESIS; CHEMICAL ANALYSIS; CHEMICAL BINDING; CHEMICAL INTERACTION; CLARA CELL; COVALENT BOND; CYTOTOXICITY; DISEASE PREDISPOSITION; DOSE RESPONSE; EXPOSURE; GOAT; HUMAN; HYPERPLASIA; INFLAMMATION; LUNG DISEASE; LUNG INJURY; LUNG PARENCHYMA; LUNG TOXICITY; METABOLISM; METABOLITE; METAPLASIA; NONHUMAN; OLFACTORY EPITHELIUM; PRIMATE; PROTEIN DEPLETION; RESPIRATORY EPITHELIUM; RESPIRATORY SYSTEM; REVIEW; RISK; SEX DIFFERENTIATION; SOLUBILITY; TISSUE NECROSIS; TOXICOKINETICS; ANIMAL; CHEMISTRY; DRUG EFFECT; INJURY;

ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; HUMANS; NAPHTHALENES; RESPIRATORY SYSTEM;

EID: 0036445603     PISSN: 03602532     EISSN: None     Source Type: Journal    
DOI: 10.1081/DMR-120015694     Document Type: Review

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