Substrate binding process and mechanistic functioning of type 1 11β-hydroxysteroid dehydrogenase from enhanced sampling methods

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Favia, Angelo D ^a   Masetti, Matteo ^b   Recanatini, Maurizio ^b   Cavalli, Andrea ^a,b  

^a ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE 1; CORTISONE;

ARTICLE; CATALYSIS; DIMERIZATION; ENZYME ACTIVITY; ENZYME BINDING; ENZYME STRUCTURE; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MUTANT; SAMPLING; SIMULATION; WILD TYPE; CHEMISTRY; GENETICS; HUMAN; METABOLISM; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1; CORTISONE; HUMANS; MOLECULAR DYNAMICS SIMULATION; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY;

EID: 80053102360     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025375     Document Type: Article

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